LCE3E and RGS20

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		LCE3E	RGS20
Gene Name		late cornified envelope 3E	regulator of G-protein signaling 20
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component		Nucleus Cytoplasm Plasma Membrane
	Molecular Function		GTPase Activator Activity Protein Binding
	Biological Process	Keratinization	Regulation Of G-protein Coupled Receptor Protein Signaling Pathway Termination Of G-protein Coupled Receptor Signaling Pathway Positive Regulation Of GTPase Activity
Pathways			Signaling by GPCR GPCR downstream signaling G alpha (z) signalling events G alpha (i) signalling events
Drugs
Diseases
GWAS		Common traits (Other) ( 20585627)
Protein-Protein Interactions		19 interactors: ADAMTSL4 HOXA1 KRT40 KRTAP10-1 KRTAP10-3 KRTAP10-5 KRTAP10-7 KRTAP10-8 KRTAP10-9 KRTAP3-2 KRTAP4-12 KRTAP4-2 KRTAP5-9 KRTAP9-2 KRTAP9-4 MDFI NOTCH2NL RGS20 SPRY2	33 interactors: ADRB2 AQP1 CATSPER1 CRCT1 CREB5 FASLG GLRX3 GNAI1 GNAI2 GNAI3 GNAO1 GNAZ HOXA1 HSPD1 INS KIF1A KLHL38 KRTAP4-2 KRTAP5-6 KRTAP5-9 LCE1B LCE2A LCE2D LCE3E LCE4A MAPKBP1 OSTM1 OTX1 PTGER3 PTPMT1 PVRL3 STMN2 TBC1D16
Entrez ID		353145	8601
HPRD ID		13975	06225
Ensembl ID		ENSG00000185966	ENSG00000147509
Uniprot IDs		Q5T5B0	H9NIM5 O76081
PDB IDs
Enriched GO Terms of Interacting Partners?		Embryonic Organ Morphogenesis Embryonic Organ Development Optokinetic Behavior Abducens Nerve Formation Inner Ear Morphogenesis Embryonic Skeletal System Morphogenesis Ear Morphogenesis Facial Nucleus Development Embryonic Morphogenesis Rhombomere 4 Development Semicircular Canal Formation Sensory Perception Of Sound Embryonic Skeletal System Development Rhombomere 3 Development Rhombomere 5 Development Sensory Perception Of Mechanical Stimulus Inner Ear Development Negative Regulation Of Neurotrophin TRK Receptor Signaling Pathway Ear Development Lung Growth Organ Morphogenesis Embryonic Neurocranium Morphogenesis Skeletal System Morphogenesis Regulation Of Neurotrophin TRK Receptor Signaling Pathway Positive Regulation Of Protein Serine/threonine Kinase Activity Negative Regulation Of Signal Transduction Outer Ear Morphogenesis Regulation Of MAP Kinase Activity Semicircular Canal Morphogenesis Protein O-linked Fucosylation Rhombomere Development Embryo Development Facial Nerve Structural Organization Pons Development Negative Regulation Of Signaling Facial Nerve Morphogenesis Bud Elongation Involved In Lung Branching Semicircular Canal Development Trophoblast Giant Cell Differentiation Negative Regulation Of Peptidyl-threonine Phosphorylation Parasympathetic Nervous System Development Negative Regulation Of Ras GTPase Activity Anatomical Structure Arrangement Negative Regulation Of Fibroblast Growth Factor Receptor Signaling Pathway Cytoplasmic Sequestering Of Transcription Factor Dorsal/ventral Axis Specification Tube Morphogenesis Positive Regulation Of MAPK Cascade Cytoplasmic Sequestering Of Protein Positive Regulation Of Protein Kinase Activity	Adenylate Cyclase-modulating G-protein Coupled Receptor Signaling Pathway G-protein Coupled Receptor Signaling Pathway, Coupled To Cyclic Nucleotide Second Messenger Keratinization Keratinocyte Differentiation Epidermis Development Developmental Process Epidermal Cell Differentiation Adenylate Cyclase-inhibiting G-protein Coupled Receptor Signaling Pathway Organ Development System Development Multicellular Organismal Development Anatomical Structure Development Skin Development Heat Generation G-protein Coupled Receptor Signaling Pathway Cell Differentiation Regulation Of Adenylate Cyclase Activity Regulation Of Cyclase Activity Tissue Development Regulation Of CAMP Biosynthetic Process Epithelium Development Regulation Of CAMP Metabolic Process Negative Regulation Of Adenylate Cyclase Activity Negative Regulation Of Lyase Activity Epithelial Cell Differentiation Temperature Homeostasis Membrane Fusion Regulation Of Body Fluid Levels Cell-cell Signaling Negative Regulation Of CAMP Biosynthetic Process Sensory Organ Development Wound Healing Bicarbonate Transport Negative Regulation Of CAMP Metabolic Process Eye Morphogenesis Cell Activation Negative Regulation Of Nucleotide Metabolic Process Acute-phase Response Regulation Of Catalytic Activity Response To Wounding Metanephric Descending Thin Limb Development Metanephric Proximal Straight Tubule Development Metanephric Proximal Convoluted Tubule Segment 2 Development Abducens Nerve Formation B Cell Cytokine Production Maintenance Of Symbiont-containing Vacuole By Host Transepithelial Water Transport Optokinetic Behavior Isotype Switching To IgG Isotypes Anion Homeostasis
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