FXYD6 and UNC119

Number of citations of the paper that reports this interaction (PMID 16169070)
531

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		FXYD6	UNC119
Gene Name		FXYD domain containing ion transport regulator 6	unc-119 homolog (C. elegans)
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Plasma Membrane Integral Component Of Membrane	Spindle Pole Centrosome Cytosol Intercellular Bridge Spindle Midzone
	Molecular Function	Molecular_function Ion Channel Activity	Protein Binding Lipid Binding
	Biological Process	Biological_process Ion Transmembrane Transport Transmembrane Transport	Endocytosis Cytokinesis, Completion Of Separation Synaptic Transmission Visual Perception Phototransduction Lipoprotein Transport Positive Regulation Of Protein Tyrosine Kinase Activity Negative Regulation Of Clathrin-mediated Endocytosis Negative Regulation Of Caveolin-mediated Endocytosis
Pathways		Ion transport by P-type ATPases Ion channel transport
Drugs
Diseases
GWAS
Protein-Protein Interactions		13 interactors: BCAR1 C4BPA CCDC90B CREB3L1 GDF9 HAUS2 PPP1CC RBM48 SLC35E1 TLE1 TP53 TRIM27 UNC119	92 interactors: AAGAB ALDH2 AMOT ANKRD24 ANXA1 ANXA3 ANXA7 ARL15 ARL2 ARL3 ARL4D ASH2L BCR BRIX1 BTBD2 C16orf74 CBX8 CCL18 CD247 CD3E CD4 CDC42 CDKN1A CDKN2C CETN3 CKMT2 CKS2 COX17 CYB561D2 EIF2S2 ERH FKBPL FXYD6 FYN GIPC2 GSTM4 HCK HLA-DQA1 HMGB1 HSPB3 HSPE1 ID2 IL5RA ITSN1 KDM1A LAMA4 LCK LIG4 LUC7L2 LYN MAPK10 MAPK8IP2 MPHOSPH6 MRPS12 ORAI2 PAFAH1B3 PAPSS1 PCDHA4 PFN1 PHF10 PIN1 PPA1 PPAP2C PSMD11 PSMD2 PTPRS QTRT1 RAP1B RCC1 RFC5 RGL2 RPA2 RPS6KA5 RUFY3 S100A4 S100A8 SAT1 SEPHS1 SERPINB9 SMN1 SULT1E1 TK1 TP53BP2 TP53I3 TRDMT1 TSC22D1 UBE2B UBE2I UBQLN4 ZAK ZFP64 ZNF24
Entrez ID		53826	9094
HPRD ID		09456	04927
Ensembl ID		ENSG00000137726	ENSG00000109103
Uniprot IDs		Q9H0Q3	Q13432
PDB IDs			3GQQ 3RBQ 4GOJ 4GOK
Enriched GO Terms of Interacting Partners?		Cell Division Transforming Growth Factor Beta Receptor Signaling Pathway Entrainment Of Circadian Clock By Photoperiod Photoperiodism Entrainment Of Circadian Clock Cellular Response To Transforming Growth Factor Beta Stimulus Response To Transforming Growth Factor Beta Regulation Of Cellular Component Organization Cellular Response To Growth Factor Stimulus Response To Growth Factor Negative Regulation Of Adaptive Immune Response Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Mitotic Cell Cycle Response To Light Stimulus Negative Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Regulation Of Cell Growth Signal Transduction Negative Regulation Of Clathrin-mediated Endocytosis Enzyme Linked Receptor Protein Signaling Pathway Signaling Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Circadian Rhythm Cell Communication Cellular Response To Organic Substance Negative Regulation Of Macromitophagy Negative Regulation Of Interleukin-2 Secretion Regulation Of Opsonization Negative Regulation Of Caveolin-mediated Endocytosis Oocyte Growth Oligodendrocyte Apoptotic Process Response To Radiation Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Regulation Of Protein Phosphorylation Negative Regulation Of Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway ER-nucleus Signaling Pathway Negative Regulation Of Cellular Response To Growth Factor Stimulus Cytokinesis, Completion Of Separation Negative Regulation Of Helicase Activity Negative Regulation Of Immune Response Positive Regulation Of Protein Metabolic Process Response To Stimulus Negative Regulation Of Complement Activation, Classical Pathway Regulation Of Progesterone Secretion Notch Signaling Pathway Regulation Of Protein Metabolic Process Positive Regulation Of Metabolic Process Regulation Of Phosphorylation Positive Regulation Of Peptidyl-tyrosine Phosphorylation Negative Regulation Of Cell Growth Cell Cycle	T Cell Costimulation Regulation Of Catalytic Activity Response To Stress Developmental Process Immune System Process Regulation Of Defense Response To Virus By Virus System Development Anatomical Structure Development Positive Regulation Of Catalytic Activity Immune Response-regulating Cell Surface Receptor Signaling Pathway Immune Response-regulating Signaling Pathway Response To Stimulus Immune Response Regulation Of Apoptotic Process Defense Response Cell Cycle Nervous System Development Regulation Of Cellular Protein Metabolic Process Multicellular Organismal Development Positive Regulation Of Cellular Protein Metabolic Process Regulation Of Cell Death Intracellular Signal Transduction Regulation Of Protein Metabolic Process Cellular Response To Stimulus Antigen Receptor-mediated Signaling Pathway Positive Regulation Of Immune System Process Positive Regulation Of Transferase Activity Immune Response-activating Cell Surface Receptor Signaling Pathway Positive Regulation Of T Cell Activation Regulation Of Cell Activation Regulation Of Cell Cycle Innate Immune Response Positive Regulation Of Homotypic Cell-cell Adhesion Positive Regulation Of Cell Activation Regulation Of Lymphocyte Activation Positive Regulation Of Protein Metabolic Process Positive Regulation Of Signal Transduction G1/S Transition Of Mitotic Cell Cycle Positive Regulation Of Cellular Metabolic Process Regulation Of Intracellular Signal Transduction Positive Regulation Of Cell-cell Adhesion Leukocyte Differentiation T Cell Receptor Signaling Pathway Regulation Of Cellular Component Organization Positive Regulation Of Protein Modification Process Viral Process Positive Regulation Of Intracellular Signal Transduction Cell Differentiation Positive Regulation Of Metabolic Process Cell Activation
Tagcloud ?		afg3l2 anapc11 arf1 calgizzarin cki dci dph2l fb1 gif gp96 gpr85 hhp2 kpdxm ksp mrps7 ohs osteosarcomas ought p110 phosphoglucoisomerase rpl13a rpl35a s11 sec34 skd3 subtracted subtractive sulphonase tapa
Tagcloud (Difference) ?		afg3l2 anapc11 arf1 calgizzarin cki dci dph2l fb1 gif gp96 gpr85 hhp2 kpdxm ksp mrps7 ohs osteosarcomas ought p110 phosphoglucoisomerase rpl13a rpl35a s11 sec34 skd3 subtracted subtractive sulphonase tapa
Tagcloud (Intersection) ?