FXYD6 and C4BPA

Number of citations of the paper that reports this interaction (PMID 21988832)
14

Data Source:
BioGRID (two hybrid)

		FXYD6	C4BPA
Gene Name		FXYD domain containing ion transport regulator 6	complement component 4 binding protein, alpha
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Plasma Membrane Integral Component Of Membrane	Extracellular Region Extracellular Space Plasma Membrane Other Organism Cell Blood Microparticle
	Molecular Function	Molecular_function Ion Channel Activity	Protein Binding Poly(A) RNA Binding
	Biological Process	Biological_process Ion Transmembrane Transport Transmembrane Transport	Complement Activation, Classical Pathway Regulation Of Complement Activation Innate Immune Response Positive Regulation Of Protein Catabolic Process Negative Regulation Of Complement Activation, Classical Pathway Regulation Of Opsonization
Pathways		Ion transport by P-type ATPases Ion channel transport	Regulation of Complement cascade Complement cascade Innate Immune System
Drugs
Diseases
GWAS			C4b binding protein levels ( 20212171)
Protein-Protein Interactions		13 interactors: BCAR1 C4BPA CCDC90B CREB3L1 GDF9 HAUS2 PPP1CC RBM48 SLC35E1 TLE1 TP53 TRIM27 UNC119	9 interactors: APCS BMPR2 FXYD6 GIT2 GTF2I LBP LRP1 PROS1 SMARCD1
Entrez ID		53826	722
HPRD ID		09456	00403
Ensembl ID		ENSG00000137726	ENSG00000123838
Uniprot IDs		Q9H0Q3	P04003 Q5VVQ8
PDB IDs			2A55 4B0F
Enriched GO Terms of Interacting Partners?		Cell Division Transforming Growth Factor Beta Receptor Signaling Pathway Entrainment Of Circadian Clock By Photoperiod Photoperiodism Entrainment Of Circadian Clock Cellular Response To Transforming Growth Factor Beta Stimulus Response To Transforming Growth Factor Beta Regulation Of Cellular Component Organization Cellular Response To Growth Factor Stimulus Response To Growth Factor Negative Regulation Of Adaptive Immune Response Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Mitotic Cell Cycle Response To Light Stimulus Negative Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Regulation Of Cell Growth Signal Transduction Negative Regulation Of Clathrin-mediated Endocytosis Enzyme Linked Receptor Protein Signaling Pathway Signaling Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Circadian Rhythm Cell Communication Cellular Response To Organic Substance Negative Regulation Of Macromitophagy Negative Regulation Of Interleukin-2 Secretion Regulation Of Opsonization Negative Regulation Of Caveolin-mediated Endocytosis Oocyte Growth Oligodendrocyte Apoptotic Process Response To Radiation Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Regulation Of Protein Phosphorylation Negative Regulation Of Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway ER-nucleus Signaling Pathway Negative Regulation Of Cellular Response To Growth Factor Stimulus Cytokinesis, Completion Of Separation Negative Regulation Of Helicase Activity Negative Regulation Of Immune Response Positive Regulation Of Protein Metabolic Process Response To Stimulus Negative Regulation Of Complement Activation, Classical Pathway Regulation Of Progesterone Secretion Notch Signaling Pathway Regulation Of Protein Metabolic Process Positive Regulation Of Metabolic Process Regulation Of Phosphorylation Positive Regulation Of Peptidyl-tyrosine Phosphorylation Negative Regulation Of Cell Growth Cell Cycle	Regulation Of Locomotion Acute-phase Response Regulation Of Inflammatory Response Artery Development Negative Regulation Of Wound Healing Regulation Of Acute Inflammatory Response Acute Inflammatory Response Beta-amyloid Clearance Regulation Of Metabolic Process Positive Regulation Of Chemotaxis Positive Regulation Of Respiratory Burst Involved In Inflammatory Response Leukocyte Chemotaxis Involved In Inflammatory Response Negative Regulation By Host Of Viral Exo-alpha-sialidase Activity Negative Regulation By Host Of Viral Glycoprotein Metabolic Process Regulation Of Lung Blood Pressure Lipopolysaccharide Transport Transition Between Slow And Fast Fiber Negative Regulation Of Exo-alpha-sialidase Activity Negative Regulation Of Chondrocyte Proliferation Positive Regulation Of Behavior Regulation Of Wound Healing Negative Regulation Of Vasoconstriction Negative Regulation Of Platelet-derived Growth Factor Receptor-beta Signaling Pathway Regulation Of Cell Migration Regulation Of Chemotaxis Regulation Of Cell Motility Regulation Of Cellular Component Movement Regulation Of Behavior Negative Regulation Of Monocyte Differentiation Positive Regulation Of Toll-like Receptor 4 Signaling Pathway Innate Immune Response Positive Regulation Of Respiratory Burst Leukocyte Migration Positive Regulation Of Axon Extension Involved In Axon Guidance Regulation Of Skeletal Muscle Adaptation Lymphatic Endothelial Cell Differentiation Negative Regulation Of Cytosolic Calcium Ion Concentration Negative Regulation Of Growth Negative Regulation Of Locomotion Phagocytosis Chromatin-mediated Maintenance Of Transcription Opsonization Regulation Of Respiratory Burst Macrophage Activation Involved In Immune Response Regulation Of Phospholipase A2 Activity Positive Regulation Of Macrophage Activation Lymphangiogenesis Response To Stress Positive Regulation Of Toll-like Receptor Signaling Pathway Negative Regulation Of Glycoprotein Metabolic Process
Tagcloud ?		afg3l2 anapc11 arf1 calgizzarin cki dci dph2l fb1 gif gp96 gpr85 hhp2 kpdxm ksp mrps7 ohs osteosarcomas ought p110 phosphoglucoisomerase rpl13a rpl35a s11 sec34 skd3 subtracted subtractive sulphonase tapa
Tagcloud (Difference) ?		afg3l2 anapc11 arf1 calgizzarin cki dci dph2l fb1 gif gp96 gpr85 hhp2 kpdxm ksp mrps7 ohs osteosarcomas ought p110 phosphoglucoisomerase rpl13a rpl35a s11 sec34 skd3 subtracted subtractive sulphonase tapa
Tagcloud (Intersection) ?