FXYD6 and HAUS2

Number of citations of the paper that reports this interaction (PubMedID 16169070)
0

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		FXYD6	HAUS2
Description		FXYD domain containing ion transport regulator 6	HAUS augmin like complex subunit 2
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GO Annotations	Cellular Component	Plasma Membrane Membrane Presynaptic Membrane Postsynaptic Membrane Glutamatergic Synapse	Cytoplasm Centrosome Spindle Cytosol Cytoskeleton Microtubule Spindle Microtubule HAUS Complex Mitotic Spindle Microtubule
	Molecular Function	Protein Binding Sodium Channel Regulator Activity Ion Channel Regulator Activity	Protein Binding
	Biological Process	Monoatomic Ion Transport Potassium Ion Transport Sodium Ion Transport Regulation Of Monoatomic Ion Transport Positive Regulation Of Sodium Ion Export Across Plasma Membrane	Microtubule Nucleation Centrosome Cycle Regulation Of Microtubule Nucleation Microtubule Organizing Center Organization Spindle Assembly Cell Division
Pathways		Ion homeostasis Ion transport by P-type ATPases Potential therapeutics for SARS	Regulation of PLK1 Activity at G2/M Transition Loss of Nlp from mitotic centrosomes Recruitment of mitotic centrosome proteins and complexes Loss of proteins required for interphase microtubule organization from the centrosome Recruitment of NuMA to mitotic centrosomes Anchoring of the basal body to the plasma membrane AURKA Activation by TPX2
Drugs
Diseases
GWAS		Hippocampal volume in Alzheimer's disease dementia ( 29274321) Myopia ( 27182965)	Bipolar disorder ( 31043756) Glucose homeostasis traits ( 25524916)
Interacting Genes		67 interacting genes: APCDD1L APH1A AQP6 ARL13B BCAR1 C4BPA CCDC90B CD74 CERS4 CLDN7 CLEC10A CREB3 CREB3L1 DERL2 EBP ELOVL2 ELOVL4 ERGIC3 FAM209A FCER1G FFAR2 FPR2 GDF9 GJA8 GPR42 HAUS2 JAGN1 KCNJ6 LHFPL2 LHFPL5 LMNA MFF MGST3 MMGT1 OCIAD1 PEX12 PGRMC2 PPP1CC RBM48 RHBDL1 RHCG RNASEK SCN3B SLC10A1 SLC10A6 SLC16A7 SLC30A2 SLC35E1 SLC35E3 SLC35H1 SLC39A2 SLC47A1 SVOP TLCD4 TLE1 TM4SF18 TMEM154 TMEM237 TMEM239 TMEM31 TMEM35A TMEM72 TMEM86B TMPPE TP53 TRIM27 UNC119	3 interacting genes: FXYD6 MAPK6 XRCC4
Entrez ID		53826	55142
HPRD ID		09456	07675
Ensembl ID		ENSG00000137726	ENSG00000137814
Uniprot IDs		Q9H0Q3	H3BP16 Q9NVX0
PDB IDs		8D3U 8D3V 8D3W 8D3X 8D3Y	7SQK
Enriched GO Terms of Interacting Partners?		Membrane Transmembrane Transport Protein Binding Endoplasmic Reticulum Membrane Endoplasmic Reticulum Antiporter Activity Carbon Dioxide Transmembrane Transporter Activity Carbon Dioxide Transmembrane Transport Bile Acid:sodium Symporter Activity Monoatomic Ion Transport Fatty Acid Elongation, Monounsaturated Fatty Acid Fatty Acid Elongase Activity Fatty Acid Elongation, Polyunsaturated Fatty Acid Fatty Acid Elongation, Saturated Fatty Acid	Septin Cytoskeleton FHA Domain Binding Positive Regulation Of Phosphatidylserine Exposure On Apoptotic Cell Surface Positive Regulation Of Phospholipid Translocation DNA-dependent Protein Kinase-DNA Ligase 4 Complex Positive Regulation Of Ligase Activity Immunoglobulin V(D)J Recombination DNA Ligase IV Complex Nonhomologous End Joining Complex Positive Regulation Of Sodium Ion Export Across Plasma Membrane Ion Channel Regulator Activity MAP Kinase Activity Response To Lithium Ion Regulation Of Plasma Membrane Organization Cellular Response To Lithium Ion Positive Regulation Of Phospholipid Transport Positive Regulation Of Sodium Ion Transmembrane Transport V(D)J Recombination Response To X-ray Protein Localization To Site Of Double-strand Break Positive Regulation Of Dendritic Spine Development Somatic Recombination Of Immunoglobulin Gene Segments Condensed Chromosome Base-excision Repair Positive Regulation Of Transport Regulation Of Sodium Ion Transmembrane Transport Sodium Channel Regulator Activity Positive Regulation Of Sodium Ion Transport Somatic Cell DNA Recombination Somatic Diversification Of Immunoglobulins Regulation Of Membrane Lipid Distribution Regulation Of Dendritic Spine Development Double-strand Break Repair Via Nonhomologous End Joining Regulation Of Sodium Ion Transport
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