SERPINF1 and SGTB

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		SERPINF1	SGTB
Description		serpin family F member 1	small glutamine rich tetratricopeptide repeat co-chaperone beta
Image			No pdb structure
GO Annotations	Cellular Component	Extracellular Region Basement Membrane Extracellular Space Axon Extracellular Matrix Melanosome Neuronal Cell Body Axon Hillock Perinuclear Region Of Cytoplasm Extracellular Exosome	Membrane TRC Complex
	Molecular Function	Serine-type Endopeptidase Inhibitor Activity Protein Binding	Protein Binding Hsp70 Protein Binding Identical Protein Binding Protein-folding Chaperone Binding Molecular Adaptor Activity
	Biological Process	Kidney Development Short-term Memory Response To Acidic PH Negative Regulation Of Endothelial Cell Migration Negative Regulation Of Gene Expression Positive Regulation Of Neuron Projection Development Negative Regulation Of Angiogenesis Ovulation Cycle Response To Arsenic-containing Substance Positive Regulation Of Neurogenesis Retina Development In Camera-type Eye Epithelial Cell Proliferation Involved In Prostate Gland Development Negative Regulation Of Epithelial Cell Proliferation Involved In Prostate Gland Development Cellular Response To Cobalt Ion Cellular Response To Retinoic Acid Cellular Response To Glucose Stimulus Cellular Response To Dexamethasone Stimulus Response To Peptide	Post-translational Protein Targeting To Endoplasmic Reticulum Membrane Protein Homooligomerization Protein Heterooligomerization
Pathways
Drugs		Copper
Diseases
GWAS		Blood protein levels ( 30072576) Calcium levels ( 20705733)	Brain morphology (MOSTest) ( 32665545) Cortical surface area (MOSTest) ( 32665545) Intralaminar thalamic nuclei volume ( 34006833) Subcortical volume (MOSTest) ( 32665545)
Interacting Genes		11 interacting genes: CSNK2A1 EPM2AIP1 IMPACT KDR LRP6 MLH1 MYOC NEDD4L PNPLA2 PTPN11 SGTB	116 interacting genes: ABCG4 ADAT2 ADIPOQ AGR2 AGR3 ASPH BTC C1QA C1QL4 C1QTNF5 C1QTNF6 C5orf46 CALR CCL3L3 CD200R1 CD3D CD68 CD79B CD99L2 CDH15 CDSN CMPK1 COL10A1 COL1A2 COLQ COMP CREB3L3 CSH1 CSH2 CTAG1A CTAG1B CYB5R1 DEFA6 DEXI DMKN ECM1 EFEMP2 EMCN ERP29 ETNK1 EVA1A FBN1 FGF21 FZD7 GALNT11 GGH GIP GPX7 GYPA HSP90B1 HSPA13 IL6R IL6ST ITPRIP ITPRIPL1 KCNE5 KRT1 LAMP3 LAT LCN2 LHB LMO2 MYDGF NAXD NME3 OSMR PAGE3 PDIA6 PGRMC1 PODXL PPIB PPIC PRAP1 PRB1 PRB3 PRB4 PRR4 PSORS1C2 RAI2 RCN1 RNASE10 RNF144A RNF144B RNF170 SDC4 SDF2L1 SELENOM SERPINE1 SERPINF1 SERPINI2 SGCA SGTA SHISA5 SIL1 SLPI SOD3 SPINK4 SPP1 SRGN SYT11 SYT4 TFF1 TMEM108 TMEM123 TMPO TMUB1 TNFRSF19 TNFSF13 TXNDC12 UBL4A UPK3A VEGFC VWC2 WFDC12 ZG16 ZG16B
Entrez ID		5176	54557
HPRD ID		01408	18049
Ensembl ID		ENSG00000132386	ENSG00000197860
Uniprot IDs		A0A140VKF3 P36955	Q96EQ0
PDB IDs		1IMV
Enriched GO Terms of Interacting Partners?		Regulation Of Membrane Depolarization Positive Regulation Of Mitochondrial Depolarization Positive Regulation Of Membrane Depolarization Wnt Signaling Pathway Positive Regulation Of Metabolic Process Negative Regulation Of DNA Recombination Double-strand Break Repair Via Nonhomologous End Joining Regulation Of Biological Quality Positive Regulation Of Catabolic Process Hsp90 Protein Binding Coreceptor Activity Positive Regulation Of Cell-matrix Adhesion Positive Regulation Of Nitric Oxide-cGMP Mediated Signal Transduction Cellular Developmental Process Regulation Of Mitochondrial Depolarization Positive Regulation Of Phosphatidylinositol 3-kinase/protein Kinase B Signal Transduction Positive Regulation Of Focal Adhesion Assembly Frizzled Binding Late Recombination Nodule Meiotic Metaphase I Homologous Chromosome Alignment Skeletal Muscle Hypertrophy Negative Regulation Of Cortisol Secretion Negative Regulation Of Growth Hormone Secretion Triglyceride Metabolic Process Regulation Of Cytoplasmic Translational Initiation In Response To Stress Receptor Tyrosine Kinase Binding Regulation Of Phosphatidylinositol 3-kinase/protein Kinase B Signal Transduction Regulation Of Focal Adhesion Assembly Regulation Of Mitochondrial Membrane Potential Positive Regulation Of Macromolecule Metabolic Process Signal Transduction Regulation Of Cell-substrate Junction Organization Meiotic Spindle Midzone Assembly Meiotic Metaphase Chromosome Alignment Chiasma ERBB Signaling Pathway Neutral Lipid Metabolic Process Acylglycerol Metabolic Process Intestinal Epithelial Cell Migration TRC Complex Positive Regulation Of Macroautophagy Protein Kinase CK2 Complex Symbiont-mediated Disruption Of Host Cell PML Body Regulation Of Metabolic Process DNA Damage Checkpoint Signaling Cellular Response To Hydrogen Sulfide Cell Differentiation Male Meiosis Chromosome Segregation MutLalpha Complex Cerebellar Cortex Formation	Extracellular Region Extracellular Space Endoplasmic Reticulum Lumen Protein Binding Collagen Trimer Endoplasmic Reticulum Chaperone Complex Endoplasmic Reticulum Extracellular Matrix Protein Folding Smooth Endoplasmic Reticulum Extracellular Matrix Structural Constituent Serine-type Endopeptidase Inhibitor Activity Sarcoplasmic Reticulum Lumen Extracellular Exosome Interleukin-6 Binding Interleukin-6 Receptor Activity Oncostatin-M Receptor Complex Melanosome Response To Bacterium Hormone Activity Interleukin-6 Receptor Complex Ciliary Neurotrophic Factor Receptor Complex Oncostatin-M Receptor Activity Positive Regulation Of Transport Memory Response To Endoplasmic Reticulum Stress Defense Response To Bacterium Ciliary Neurotrophic Factor Receptor Activity Interleukin-11 Receptor Activity Interleukin-11 Binding Oncostatin-M-mediated Signaling Pathway Regulation Of Smooth Muscle Cell-matrix Adhesion Regulation Of Immune System Process Sequestering Of Calcium Ion Biomineral Tissue Development Basement Membrane Ciliary Neurotrophic Factor-mediated Signaling Pathway ERAD Pathway Growth Factor Activity Golgi Lumen Positive Regulation Of Acute Inflammatory Response Ciliary Neurotrophic Factor Receptor Binding Response To Stress Regulation Of Cell-substrate Adhesion
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