SERPINF1 and EPM2AIP1

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		SERPINF1	EPM2AIP1
Gene Name		serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1	EPM2A (laforin) interacting protein 1
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Extracellular Region Basement Membrane Extracellular Space Extracellular Matrix Melanosome Axon Hillock Perinuclear Region Of Cytoplasm Extracellular Vesicular Exosome	Nucleus Endoplasmic Reticulum
	Molecular Function	Serine-type Endopeptidase Inhibitor Activity
	Biological Process	Kidney Development Multicellular Organismal Development Aging Short-term Memory Cell Proliferation Response To Acidic PH Negative Regulation Of Endothelial Cell Migration Negative Regulation Of Endopeptidase Activity Positive Regulation Of Neuron Projection Development Negative Regulation Of Angiogenesis Ovulation Cycle Response To Arsenic-containing Substance Negative Regulation Of Inflammatory Response Positive Regulation Of Neurogenesis Retina Development In Camera-type Eye Negative Regulation Of Epithelial Cell Proliferation Involved In Prostate Gland Development Cellular Response To Cobalt Ion Cellular Response To Retinoic Acid Cellular Response To Glucose Stimulus Cellular Response To Dexamethasone Stimulus Negative Regulation Of Neuron Death	Response To Insulin Positive Regulation Of Glycogen Biosynthetic Process Positive Regulation Of Glycogen (starch) Synthase Activity
Pathways
Drugs
Diseases
GWAS		Calcium levels ( 20705733)
Protein-Protein Interactions		7 interactors: CSNK2A1 EPM2AIP1 LRP6 MLH1 MYOC NEDD4L PNPLA2	16 interactors: ACTN1 C1orf50 CCNB1IP1 CPSF7 EMP2 EPM2A FHL3 KCTD1 MEOX2 PRTFDC1 REL SERPINF1 TNFAIP1 TRIM54 VPS52 ZBTB14
Entrez ID		5176	9852
HPRD ID		01408	07445
Ensembl ID		ENSG00000132386	ENSG00000178567
Uniprot IDs		P36955	Q7L775
PDB IDs		1IMV
Enriched GO Terms of Interacting Partners?		Regulation Of Membrane Depolarization Wnt Signaling Pathway Regulation Of Cell Junction Assembly Positive Regulation Of Wnt Signaling Pathway Involved In Dorsal/ventral Axis Specification Canonical Wnt Signaling Pathway Involved In Cardiac Neural Crest Cell Differentiation Involved In Heart Development Negative Regulation Of Planar Cell Polarity Pathway Involved In Neural Tube Closure Negative Regulation Of Planar Cell Polarity Pathway Involved In Outflow Tract Morphogenesis Negative Regulation Of Planar Cell Polarity Pathway Involved In Pericardium Morphogenesis Negative Regulation Of Planar Cell Polarity Pathway Involved In Cardiac Right Atrium Morphogenesis Negative Regulation Of Planar Cell Polarity Pathway Involved In Cardiac Muscle Tissue Morphogenesis Negative Regulation Of Planar Cell Polarity Pathway Involved In Ventricular Septum Morphogenesis Skeletal Muscle Hypertrophy Meiotic Metaphase I Plate Congression ERBB2-ERBB3 Signaling Pathway Meiotic Spindle Midzone Assembly Regulation Of Metabolic Process External Genitalia Morphogenesis Wnt Signaling Pathway Involved In Forebrain Neuroblast Division Negative Regulation Of Mitotic Recombination Regulation Of Planar Cell Polarity Pathway Involved In Neural Tube Closure ERBB2 Signaling Pathway Receptor-mediated Endocytosis Of Low-density Lipoprotein Particle Involved In Cholesterol Transport Positive Regulation Of Caveolin-mediated Endocytosis Canonical Wnt Signaling Pathway Involved In Neural Crest Cell Differentiation Positive Regulation Of Wnt Signaling Pathway Regulation Of Ion Homeostasis Cell Development Positive Regulation Of Metabolic Process Regulation Of Mitotic Recombination Male Meiosis Chromosome Segregation Axis Elongation Involved In Somitogenesis Neural Crest Formation Wnt Signaling Pathway Involved In Dorsal/ventral Axis Specification Glial Cell Differentiation Positive Regulation Of Glycogen (starch) Synthase Activity Mammary Placode Formation Negative Regulation Of Wnt Signaling Pathway Involved In Heart Development Acylglycerol Acyl-chain Remodeling Pericardium Morphogenesis Forebrain Radial Glial Cell Differentiation Negative Regulation Of Sodium Ion Transmembrane Transporter Activity Non-canonical Wnt Signaling Pathway Via JNK Cascade Regulation Of Caveolin-mediated Endocytosis Positive Regulation Of Protein Catabolic Process Negative Regulation Of Cellular Metabolic Process Bone Development Canonical Wnt Signaling Pathway Involved In Positive Regulation Of Cardiac Outflow Tract Cell Proliferation Wnt Signaling Pathway Involved In Somitogenesis Non-canonical Wnt Signaling Pathway Via MAPK Cascade Negative Regulation Of Sodium Ion Transmembrane Transport	Actin Cytoskeleton Organization Multicellular Organismal Development Cellular Component Assembly Actin Filament-based Process Actin Filament Bundle Assembly Actin Filament Organization Developmental Process Cellular Response To Cobalt Ion Embryonic Ectodermal Digestive Tract Development Regulation Of Endothelial Cell Migration Habituation Protein Oligomerization Cellular Macromolecule Biosynthetic Process Protein Localization To Tight Junction Macromolecule Biosynthetic Process
Tagcloud ?		cel coexpressions colocalization cyst cysts die exhaustively glycoproteins lac lipase lysozyme m1 mapping mining muc6 mucin mucinous multilectin nano nonglycoproteins nonmucinous novoseek ontology periostin pigment proteomic pyruvate quantitation ywhae
Tagcloud (Difference) ?		cel coexpressions colocalization cyst cysts die exhaustively glycoproteins lac lipase lysozyme m1 mapping mining muc6 mucin mucinous multilectin nano nonglycoproteins nonmucinous novoseek ontology periostin pigment proteomic pyruvate quantitation ywhae
Tagcloud (Intersection) ?