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UBE2D4 and RNF115
Number of citations of the paper that reports this interaction (PMID
19690564
)
33
Data Source:
BioGRID
(two hybrid, two hybrid)
UBE2D4
RNF115
Gene Name
ubiquitin-conjugating enzyme E2D 4 (putative)
ring finger protein 115
Image
No pdb structure
No pdb structure
Gene Ontology Annotations
Cellular Component
Cytosol
Molecular Function
Ubiquitin-protein Transferase Activity
Protein Binding
ATP Binding
Ligase Activity
Ubiquitin Conjugating Enzyme Activity
Ubiquitin-protein Transferase Activity
Protein Binding
Zinc Ion Binding
Ligase Activity
Ubiquitin Protein Ligase Activity
Biological Process
Protein Ubiquitination
Protein K29-linked Ubiquitination
Protein K27-linked Ubiquitination
Protein K63-linked Ubiquitination
Protein K48-linked Ubiquitination
Protein K11-linked Ubiquitination
Protein K6-linked Ubiquitination
Negative Regulation Of Epidermal Growth Factor Receptor Signaling Pathway
Ubiquitin-dependent Protein Catabolic Process Via The Multivesicular Body Sorting Pathway
Protein Autoubiquitination
Protein K63-linked Ubiquitination
Protein K48-linked Ubiquitination
Pathways
Antigen processing: Ubiquitination & Proteasome degradation
Class I MHC mediated antigen processing & presentation
Adaptive Immune System
Drugs
Diseases
GWAS
Protein-Protein Interactions
90 interactors:
AMFR
ARIH2
BFAR
BIRC8
CADPS2
CHFR
CNOT4
DAZAP2
DTX1
DTX2
DTX3
DTX3L
DZIP3
INCA1
LRSAM1
MAGEA11
MAP3K1
MARCH3
MGRN1
MIB1
MID1
MID2
MKRN2
MKRN3
MUL1
MYBL2
MYLIP
OTUB1
PHF7
PJA2
RBCK1
RCHY1
RFWD3
RING1
RLIM
RMND5B
RNF10
RNF103
RNF11
RNF111
RNF114
RNF115
RNF125
RNF126
RNF13
RNF130
RNF138
RNF14
RNF150
RNF165
RNF166
RNF167
RNF181
RNF185
RNF2
RNF25
RNF26
RNF38
RNF4
RNF43
RNF5
RNF7
SIAH1
TOPORS
TRAF6
TRAF7
TRIM10
TRIM17
TRIM2
TRIM25
TRIM27
TRIM3
TRIM31
TRIM35
TRIM38
TRIM39
TRIM43
TRIM45
TRIM5
TRIM50
TRIM8
UBE4A
UBOX5
UBTD1
UFM1
UHRF2
XIAP
ZNRF1
ZNRF2
ZNRF4
27 interactors:
AKT1
APP
ATN1
CDK10
CST3
DAZAP2
DOCK4
EGFR
FOLR3
HRAS
IGHA1
MDM4
MFAP4
RAB7A
RAD23A
RPL18A
SSSCA1
TTR
UBE2D1
UBE2D2
UBE2D3
UBE2D4
UBE2E1
UBE2E3
UBE2I
UBE2N
UBE2W
Entrez ID
51619
27246
HPRD ID
14242
18328
Ensembl ID
ENSG00000078967
Uniprot IDs
Q9Y2X8
Q9Y4L5
PDB IDs
Enriched GO Terms of Interacting Partners
?
Protein Modification By Small Protein Conjugation
Protein Ubiquitination
Cellular Protein Modification Process
Cellular Protein Metabolic Process
Protein Metabolic Process
Protein Polyubiquitination
Protein Autoubiquitination
Cellular Metabolic Process
Ubiquitin-dependent Protein Catabolic Process
Modification-dependent Protein Catabolic Process
Protein Catabolic Process
Proteolysis Involved In Cellular Protein Catabolic Process
Cellular Protein Catabolic Process
Cellular Macromolecule Catabolic Process
Protein K63-linked Ubiquitination
Regulation Of Viral Entry Into Host Cell
Protein K48-linked Ubiquitination
Regulation Of Viral Release From Host Cell
Negative Regulation Of Viral Release From Host Cell
Negative Regulation Of Viral Entry Into Host Cell
Metabolic Process
Negative Regulation Of Viral Process
Catabolic Process
Proteolysis
Protein Ubiquitination Involved In Ubiquitin-dependent Protein Catabolic Process
Positive Regulation Of Sequence-specific DNA Binding Transcription Factor Activity
Regulation Of Viral Process
Protein Monoubiquitination
Positive Regulation Of NF-kappaB Transcription Factor Activity
Regulation Of Sequence-specific DNA Binding Transcription Factor Activity
Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process
Proteasomal Protein Catabolic Process
Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling
Positive Regulation Of Signal Transduction
Negative Regulation Of Viral Transcription
Regulation Of I-kappaB Kinase/NF-kappaB Signaling
Cellular Process
Regulation Of Signal Transduction
Innate Immune Response
Interferon-gamma-mediated Signaling Pathway
Regulation Of Protein Ubiquitination
Cellular Response To Interferon-gamma
Regulation Of Signaling
Positive Regulation Of Intracellular Signal Transduction
Apoptotic Process
Response To Interferon-gamma
Programmed Cell Death
Cell Death
Death
Histone Monoubiquitination
Protein K48-linked Ubiquitination
Protein Polyubiquitination
Protein Ubiquitination
Protein Modification By Small Protein Conjugation
Protein Catabolic Process
Cellular Protein Catabolic Process
Protein K11-linked Ubiquitination
Cellular Macromolecule Catabolic Process
Ubiquitin-dependent Protein Catabolic Process
Modification-dependent Protein Catabolic Process
Cellular Response To Hypoxia
Cellular Response To Decreased Oxygen Levels
Proteolysis Involved In Cellular Protein Catabolic Process
Response To Abiotic Stimulus
Cellular Response To Oxygen Levels
Regulation Of Protein Catabolic Process
Cellular Protein Metabolic Process
Negative Regulation Of Protein Catabolic Process
Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process
Proteasomal Protein Catabolic Process
Immune Response-regulating Signaling Pathway
Defense Response
Catabolic Process
Cellular Protein Modification Process
Response To Light Stimulus
Innate Immune Response
Positive Regulation Of Transferase Activity
Toll-like Receptor 4 Signaling Pathway
Regulation Of Transcription From RNA Polymerase II Promoter In Response To Hypoxia
Regulation Of Cell Cycle
Regulation Of Mitotic Cell Cycle
Immune Response
Protein Metabolic Process
Mitotic Cell Cycle Process
Toll-like Receptor Signaling Pathway
Protein K63-linked Ubiquitination
Response To Radiation
Cell Cycle Process
Regulation Of Cell Cycle Process
Mitotic Cell Cycle
Regulation Of Transcription From RNA Polymerase II Promoter
Pattern Recognition Receptor Signaling Pathway
Innate Immune Response-activating Signal Transduction
Protein Monoubiquitination
Regulation Of Metabolic Process
Response To Hypoxia
Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process
Response To UV-A
Activation Of Innate Immune Response
Response To Stress
Tagcloud
?
accumulation
apoptosis
apoptotic
arsenic
cadmium
conjugating
degradation
downregulation
elevated
enzymes
family
hand
induce
inorganic
mercury
p53
promote
proteasomal
proximal
rat
suppressed
suppression
tubular
ubiquitin
ubiquitination
Tagcloud (Difference)
?
accumulation
apoptosis
apoptotic
arsenic
cadmium
conjugating
degradation
downregulation
elevated
enzymes
family
hand
induce
inorganic
mercury
p53
promote
proteasomal
proximal
rat
suppressed
suppression
tubular
ubiquitin
ubiquitination
Tagcloud (Intersection)
?