UBE2D4 and RCHY1

  • Number of citations of the paper that reports this interaction (PMID 19549727)
  • 40
  • Data Source:
  • BioGRID (two hybrid)

UBE2D4

RCHY1

Gene Name ubiquitin-conjugating enzyme E2D 4 (putative) ring finger and CHY zinc finger domain containing 1, E3 ubiquitin protein ligase
Image No pdb structure
Gene Ontology Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Response to tocilizumab in rheumatoid arthritis ( 22491018)
Protein-Protein Interactions 90 interactors: AMFR ARIH2 BFAR BIRC8 CADPS2 CHFR CNOT4 DAZAP2 DTX1 DTX2 DTX3 DTX3L DZIP3 INCA1 LRSAM1 MAGEA11 MAP3K1 MARCH3 MGRN1 MIB1 MID1 MID2 MKRN2 MKRN3 MUL1 MYBL2 MYLIP OTUB1 PHF7 PJA2 RBCK1 RCHY1 RFWD3 RING1 RLIM RMND5B RNF10 RNF103 RNF11 RNF111 RNF114 RNF115 RNF125 RNF126 RNF13 RNF130 RNF138 RNF14 RNF150 RNF165 RNF166 RNF167 RNF181 RNF185 RNF2 RNF25 RNF26 RNF38 RNF4 RNF43 RNF5 RNF7 SIAH1 TOPORS TRAF6 TRAF7 TRIM10 TRIM17 TRIM2 TRIM25 TRIM27 TRIM3 TRIM31 TRIM35 TRIM38 TRIM39 TRIM43 TRIM45 TRIM5 TRIM50 TRIM8 UBE4A UBOX5 UBTD1 UFM1 UHRF2 XIAP ZNRF1 ZNRF2 ZNRF4 61 interactors: ADAMTSL4 AIG1 AOX1 AR ARF4 ATN1 BIRC3 C19orf80 CAMK2A CAMK2G CDK9 CDKN1B CHD8 CHEK2 COPE COX6C CYBA DCUN1D5 F7 FADS6 GFI1B GORAB HRG KAT5 KLHL41 KRTAP9-2 LIMS2 MDM2 MEOX2 MSH3 MT2A NKD2 NLK NOTCH2NL PGLS PLAGL2 PMM1 PRDX4 RAB11A RBM38 RILP RPLP1 RPN2 SEMA4C SERPINA1 SERPINA5 SERTAD1 SRPRB TAOK2 TMBIM1 TMEM14C TMEM184A TP53 TP63 TP73 TRIM8 UBASH3B UBE2D2 UBE2D4 WDR74 ZNF160
Entrez ID 51619 25898
HPRD ID 14242 07607
Ensembl ID ENSG00000078967 ENSG00000163743
Uniprot IDs Q9Y2X8 C7E542 E7EMC8 E7ETW5 J3KPI0 Q96PM5
PDB IDs 2JRJ 2K2C 2K2D
Enriched GO Terms of Interacting Partners?
Tagcloud ?
accumulation  apoptosis  apoptotic  arsenic  cadmium  conjugating  degradation  downregulation  elevated  enzymes  family  hand  induce  inorganic  mercury  p53  promote  proteasomal  proximal  rat  suppressed  suppression  tubular  ubiquitin  ubiquitination 
20s  alters  animal  conserved  correlatively  crucial  degradation  display  e3  establish  handful  homeodomain  hox  hoxa2  interacts  ligase  modes  multitude  pirh2  promotes  proteasomal  proteasome  regulators  reports  reveal  stabilization  subunits  ubiquitin  ubiquitination 
Tagcloud (Difference) ?
accumulation  apoptosis  apoptotic  arsenic  cadmium  conjugating  downregulation  elevated  enzymes  family  hand  induce  inorganic  mercury  p53  promote  proximal  rat  suppressed  suppression  tubular 
20s  alters  animal  conserved  correlatively  crucial  display  e3  establish  handful  homeodomain  hox  hoxa2  interacts  ligase  modes  multitude  pirh2  promotes  proteasome  regulators  reports  reveal  stabilization  subunits 
Tagcloud (Intersection) ?
degradation  proteasomal  ubiquitin  ubiquitination