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RNF115 and MFAP4
Number of citations of the paper that reports this interaction (PubMedID
22315970
)
45
Data Source:
BioGRID
(two hybrid)
RNF115
MFAP4
Description
ring finger protein 115
microfibril associated protein 4
Image
No pdb structure
GO Annotations
Cellular Component
Nucleus
Cytoplasm
Endoplasmic Reticulum
Golgi Apparatus
Cytosol
Microfibril
Extracellular Region
Extracellular Space
Extracellular Matrix
Elastic Fiber
Molecular Function
Ubiquitin-protein Transferase Activity
Protein Binding
Zinc Ion Binding
Transferase Activity
Metal Ion Binding
Ubiquitin Protein Ligase Activity
Extracellular Matrix Structural Constituent
Protein Binding
Biological Process
Protein Polyubiquitination
Endoplasmic Reticulum To Golgi Vesicle-mediated Transport
Golgi To Plasma Membrane Transport
Protein Ubiquitination
Negative Regulation Of Toll-like Receptor Signaling Pathway
Positive Regulation Of Toll-like Receptor Signaling Pathway
Toll-like Receptor 4 Signaling Pathway
Negative Regulation Of Epidermal Growth Factor Receptor Signaling Pathway
Ubiquitin-dependent Protein Catabolic Process Via The Multivesicular Body Sorting Pathway
Protein Autoubiquitination
Protein K63-linked Ubiquitination
Protein K48-linked Ubiquitination
Protein K11-linked Ubiquitination
Cell Adhesion
UV Protection
Regulation Of Collagen Metabolic Process
Elastic Fiber Assembly
Cellular Response To UV-B
Supramolecular Fiber Organization
Pathways
Antigen processing: Ubiquitination & Proteasome degradation
Molecules associated with elastic fibres
Drugs
Diseases
GWAS
Apolipoprotein A1 levels (
32203549
)
Breast cancer (
25751625
29059683
)
HDL cholesterol levels (
32203549
)
Platelet distribution width (
32888494
)
Youthful appearance (self-reported) (
32339537
)
Interacting Genes
34 interacting genes:
AKT1
APP
ATN1
CDK10
CST3
DAZAP2
DOCK4
EGFR
FOLR3
HRAS
IGHA1
MAVS
MDM2
MDM4
MFAP4
NFKBIA
RAB7A
RAD23A
RPL18A
STING1
TTR
UBC
UBE2D1
UBE2D2
UBE2D3
UBE2D4
UBE2E1
UBE2E2
UBE2E3
UBE2I
UBE2N
USP9X
VCP
ZNRD2
2 interacting genes:
RNF115
SFTPD
Entrez ID
27246
4239
HPRD ID
18328
02789
Ensembl ID
ENSG00000265491
ENSG00000166482
Uniprot IDs
Q9Y4L5
P55083
PDB IDs
7ZMK
8UN7
Enriched GO Terms of Interacting Partners
?
Ubiquitin Conjugating Enzyme Activity
Protein Modification By Small Protein Conjugation
Protein Ubiquitination
Post-translational Protein Modification
Ubiquitin-protein Transferase Activity
Protein Polyubiquitination
Modification-dependent Protein Catabolic Process
Protein K48-linked Ubiquitination
Regulation Of Protein Catabolic Process
Proteolysis Involved In Protein Catabolic Process
Ubiquitin-dependent Protein Catabolic Process
Protein K11-linked Ubiquitination
Protein Modification Process
Positive Regulation Of G1/S Transition Of Mitotic Cell Cycle
Macromolecule Catabolic Process
Nucleotide Binding
Protein Metabolic Process
Protein Monoubiquitination
Protein Serine/threonine Kinase Binding
Ubiquitin Protein Ligase Binding
Positive Regulation Of Cell Cycle G1/S Phase Transition
Protein-containing Complex
Positive Regulation Of Mitotic Cell Cycle
Proteolysis
Positive Regulation Of Mitotic Cell Cycle Phase Transition
ATP Binding
Regulation Of Metabolic Process
Positive Regulation Of Cell Cycle Phase Transition
Positive Regulation Of Protein Catabolic Process
Positive Regulation Of Cell Cycle
Intracellular Signal Transduction
Immune Response-activating Signaling Pathway
Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process
Regulation Of Macromolecule Metabolic Process
Regulation Of Proteolysis
Positive Regulation Of Intracellular Signal Transduction
Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process
Catabolic Process
Enzyme Binding
Negative Regulation Of Macromolecule Metabolic Process
Negative Regulation Of Cilium Assembly
Protein K63-linked Ubiquitination
Regulation Of G1/S Transition Of Mitotic Cell Cycle
Immune Response-regulating Signaling Pathway
Regulation Of Intracellular Signal Transduction
Transferase Activity
Activation Of Immune Response
Protein K6-linked Ubiquitination
Positive Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process
Traversing Start Control Point Of Mitotic Cell Cycle
Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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