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UBE2D4 and TRIM43
Number of citations of the paper that reports this interaction (PMID
19549727
)
40
Data Source:
BioGRID
(two hybrid)
UBE2D4
TRIM43
Gene Name
ubiquitin-conjugating enzyme E2D 4 (putative)
tripartite motif containing 43
Image
No pdb structure
No pdb structure
Gene Ontology Annotations
Cellular Component
Intracellular
Molecular Function
Ubiquitin-protein Transferase Activity
Protein Binding
ATP Binding
Ligase Activity
Ubiquitin Conjugating Enzyme Activity
Zinc Ion Binding
Biological Process
Protein Ubiquitination
Protein K29-linked Ubiquitination
Protein K27-linked Ubiquitination
Protein K63-linked Ubiquitination
Protein K48-linked Ubiquitination
Protein K11-linked Ubiquitination
Protein K6-linked Ubiquitination
Pathways
Antigen processing: Ubiquitination & Proteasome degradation
Class I MHC mediated antigen processing & presentation
Adaptive Immune System
Drugs
Diseases
GWAS
Protein-Protein Interactions
90 interactors:
AMFR
ARIH2
BFAR
BIRC8
CADPS2
CHFR
CNOT4
DAZAP2
DTX1
DTX2
DTX3
DTX3L
DZIP3
INCA1
LRSAM1
MAGEA11
MAP3K1
MARCH3
MGRN1
MIB1
MID1
MID2
MKRN2
MKRN3
MUL1
MYBL2
MYLIP
OTUB1
PHF7
PJA2
RBCK1
RCHY1
RFWD3
RING1
RLIM
RMND5B
RNF10
RNF103
RNF11
RNF111
RNF114
RNF115
RNF125
RNF126
RNF13
RNF130
RNF138
RNF14
RNF150
RNF165
RNF166
RNF167
RNF181
RNF185
RNF2
RNF25
RNF26
RNF38
RNF4
RNF43
RNF5
RNF7
SIAH1
TOPORS
TRAF6
TRAF7
TRIM10
TRIM17
TRIM2
TRIM25
TRIM27
TRIM3
TRIM31
TRIM35
TRIM38
TRIM39
TRIM43
TRIM45
TRIM5
TRIM50
TRIM8
UBE4A
UBOX5
UBTD1
UFM1
UHRF2
XIAP
ZNRF1
ZNRF2
ZNRF4
10 interactors:
ENOX1
MYOG
TRIM27
TRIM8
UBE2D1
UBE2D2
UBE2D3
UBE2D4
UBE2G2
UBE2K
Entrez ID
51619
129868
HPRD ID
14242
15560
Ensembl ID
ENSG00000078967
ENSG00000144015
Uniprot IDs
Q9Y2X8
Q96BQ3
PDB IDs
Enriched GO Terms of Interacting Partners
?
Protein Modification By Small Protein Conjugation
Protein Ubiquitination
Cellular Protein Modification Process
Cellular Protein Metabolic Process
Protein Metabolic Process
Protein Polyubiquitination
Protein Autoubiquitination
Cellular Metabolic Process
Ubiquitin-dependent Protein Catabolic Process
Modification-dependent Protein Catabolic Process
Protein Catabolic Process
Proteolysis Involved In Cellular Protein Catabolic Process
Cellular Protein Catabolic Process
Cellular Macromolecule Catabolic Process
Protein K63-linked Ubiquitination
Regulation Of Viral Entry Into Host Cell
Protein K48-linked Ubiquitination
Regulation Of Viral Release From Host Cell
Negative Regulation Of Viral Release From Host Cell
Negative Regulation Of Viral Entry Into Host Cell
Metabolic Process
Negative Regulation Of Viral Process
Catabolic Process
Proteolysis
Protein Ubiquitination Involved In Ubiquitin-dependent Protein Catabolic Process
Positive Regulation Of Sequence-specific DNA Binding Transcription Factor Activity
Regulation Of Viral Process
Protein Monoubiquitination
Positive Regulation Of NF-kappaB Transcription Factor Activity
Regulation Of Sequence-specific DNA Binding Transcription Factor Activity
Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process
Proteasomal Protein Catabolic Process
Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling
Positive Regulation Of Signal Transduction
Negative Regulation Of Viral Transcription
Regulation Of I-kappaB Kinase/NF-kappaB Signaling
Cellular Process
Regulation Of Signal Transduction
Innate Immune Response
Interferon-gamma-mediated Signaling Pathway
Regulation Of Protein Ubiquitination
Cellular Response To Interferon-gamma
Regulation Of Signaling
Positive Regulation Of Intracellular Signal Transduction
Apoptotic Process
Response To Interferon-gamma
Programmed Cell Death
Cell Death
Death
Histone Monoubiquitination
Protein K48-linked Ubiquitination
Protein Polyubiquitination
Protein Ubiquitination
Protein Modification By Small Protein Conjugation
Regulation Of Transcription From RNA Polymerase II Promoter In Response To Hypoxia
Ubiquitin-dependent Protein Catabolic Process
Modification-dependent Protein Catabolic Process
Regulation Of Transcription From RNA Polymerase II Promoter In Response To Stress
Regulation Of DNA-templated Transcription In Response To Stress
Proteolysis Involved In Cellular Protein Catabolic Process
Cellular Protein Catabolic Process
TRIF-dependent Toll-like Receptor Signaling Pathway
Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process
MyD88-independent Toll-like Receptor Signaling Pathway
Toll-like Receptor 3 Signaling Pathway
Protein Catabolic Process
Proteasomal Protein Catabolic Process
Cellular Protein Modification Process
Toll-like Receptor 4 Signaling Pathway
Cellular Response To Hypoxia
Cellular Response To Decreased Oxygen Levels
Innate Immune Response
Toll-like Receptor Signaling Pathway
Cellular Response To Oxygen Levels
Cellular Macromolecule Catabolic Process
Negative Regulation Of Viral Release From Host Cell
Pattern Recognition Receptor Signaling Pathway
Innate Immune Response-activating Signal Transduction
Activation Of Innate Immune Response
Negative Regulation Of Viral Transcription
Regulation Of Viral Release From Host Cell
Protein K11-linked Ubiquitination
Cellular Protein Metabolic Process
Positive Regulation Of Innate Immune Response
Protein K63-linked Ubiquitination
Immune Response
Defense Response
Regulation Of Innate Immune Response
Proteolysis
Response To Hypoxia
Protein Metabolic Process
Regulation Of Immune Response
Regulation Of Viral Transcription
Negative Regulation Of Viral Process
Positive Regulation Of Muscle Atrophy
Catabolic Process
BMP Signaling Pathway
Regulation Of Transcription From RNA Polymerase II Promoter
Response To Abiotic Stimulus
Immune Response-regulating Signaling Pathway
Tagcloud
?
accumulation
apoptosis
apoptotic
arsenic
cadmium
conjugating
degradation
downregulation
elevated
enzymes
family
hand
induce
inorganic
mercury
p53
promote
proteasomal
proximal
rat
suppressed
suppression
tubular
ubiquitin
ubiquitination
Tagcloud (Difference)
?
accumulation
apoptosis
apoptotic
arsenic
cadmium
conjugating
degradation
downregulation
elevated
enzymes
family
hand
induce
inorganic
mercury
p53
promote
proteasomal
proximal
rat
suppressed
suppression
tubular
ubiquitin
ubiquitination
Tagcloud (Intersection)
?