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RNF115
Gene Name
ring finger protein 115
Image
No pdb structure
Gene Ontology Annotations
Cellular Component
Cytosol
Molecular Function
Ubiquitin-protein Transferase Activity
Protein Binding
Zinc Ion Binding
Ligase Activity
Ubiquitin Protein Ligase Activity
Biological Process
Negative Regulation Of Epidermal Growth Factor Receptor Signaling Pathway
Ubiquitin-dependent Protein Catabolic Process Via The Multivesicular Body Sorting Pathway
Protein Autoubiquitination
Protein K63-linked Ubiquitination
Protein K48-linked Ubiquitination
Pathways
Drugs
Diseases
GWAS
Protein-protein Interactions
27 interactors:
AKT1
APP
ATN1
CDK10
CST3
DAZAP2
DOCK4
EGFR
FOLR3
HRAS
IGHA1
MDM4
MFAP4
RAB7A
RAD23A
RPL18A
SSSCA1
TTR
UBE2D1
UBE2D2
UBE2D3
UBE2D4
UBE2E1
UBE2E3
UBE2I
UBE2N
UBE2W
Entrez ID
27246
HPRD ID
18328
Ensembl ID
Uniprot IDs
Q9Y4L5
PDB IDs
Enriched GO Terms of Interacting Partners
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Protein K48-linked Ubiquitination
Protein Polyubiquitination
Protein Ubiquitination
Protein Modification By Small Protein Conjugation
Protein Catabolic Process
Cellular Protein Catabolic Process
Protein K11-linked Ubiquitination
Cellular Macromolecule Catabolic Process
Ubiquitin-dependent Protein Catabolic Process
Modification-dependent Protein Catabolic Process
Cellular Response To Hypoxia
Cellular Response To Decreased Oxygen Levels
Proteolysis Involved In Cellular Protein Catabolic Process
Response To Abiotic Stimulus
Cellular Response To Oxygen Levels
Regulation Of Protein Catabolic Process
Cellular Protein Metabolic Process
Negative Regulation Of Protein Catabolic Process
Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process
Proteasomal Protein Catabolic Process
Immune Response-regulating Signaling Pathway
Defense Response
Catabolic Process
Cellular Protein Modification Process
Response To Light Stimulus
Innate Immune Response
Positive Regulation Of Transferase Activity
Toll-like Receptor 4 Signaling Pathway
Regulation Of Transcription From RNA Polymerase II Promoter In Response To Hypoxia
Regulation Of Cell Cycle
Regulation Of Mitotic Cell Cycle
Immune Response
Protein Metabolic Process
Mitotic Cell Cycle Process
Toll-like Receptor Signaling Pathway
Protein K63-linked Ubiquitination
Response To Radiation
Cell Cycle Process
Regulation Of Cell Cycle Process
Mitotic Cell Cycle
Regulation Of Transcription From RNA Polymerase II Promoter
Pattern Recognition Receptor Signaling Pathway
Innate Immune Response-activating Signal Transduction
Protein Monoubiquitination
Regulation Of Metabolic Process
Response To Hypoxia
Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process
Response To UV-A
Activation Of Innate Immune Response
Response To Stress
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