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UBE2D4 and MID2
Number of citations of the paper that reports this interaction (PMID
21143188
)
10
Data Source:
BioGRID
(two hybrid, two hybrid)
UBE2D4
MID2
Gene Name
ubiquitin-conjugating enzyme E2D 4 (putative)
midline 2
Image
No pdb structure
Gene Ontology Annotations
Cellular Component
Cytoplasm
Microtubule
Extracellular Vesicular Exosome
Molecular Function
Ubiquitin-protein Transferase Activity
Protein Binding
ATP Binding
Ligase Activity
Ubiquitin Conjugating Enzyme Activity
Microtubule Binding
Zinc Ion Binding
Ligase Activity
Protein Homodimerization Activity
Protein Heterodimerization Activity
Phosphoprotein Binding
Biological Process
Protein Ubiquitination
Protein K29-linked Ubiquitination
Protein K27-linked Ubiquitination
Protein K63-linked Ubiquitination
Protein K48-linked Ubiquitination
Protein K11-linked Ubiquitination
Protein K6-linked Ubiquitination
Protein Ubiquitination
Negative Regulation Of Viral Transcription
Protein Localization To Microtubule
Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling
Innate Immune Response
Negative Regulation Of Viral Entry Into Host Cell
Positive Regulation Of Sequence-specific DNA Binding Transcription Factor Activity
Positive Regulation Of NF-kappaB Transcription Factor Activity
Negative Regulation Of Viral Release From Host Cell
Pathways
Antigen processing: Ubiquitination & Proteasome degradation
Class I MHC mediated antigen processing & presentation
Adaptive Immune System
Drugs
Diseases
GWAS
Protein-Protein Interactions
90 interactors:
AMFR
ARIH2
BFAR
BIRC8
CADPS2
CHFR
CNOT4
DAZAP2
DTX1
DTX2
DTX3
DTX3L
DZIP3
INCA1
LRSAM1
MAGEA11
MAP3K1
MARCH3
MGRN1
MIB1
MID1
MID2
MKRN2
MKRN3
MUL1
MYBL2
MYLIP
OTUB1
PHF7
PJA2
RBCK1
RCHY1
RFWD3
RING1
RLIM
RMND5B
RNF10
RNF103
RNF11
RNF111
RNF114
RNF115
RNF125
RNF126
RNF13
RNF130
RNF138
RNF14
RNF150
RNF165
RNF166
RNF167
RNF181
RNF185
RNF2
RNF25
RNF26
RNF38
RNF4
RNF43
RNF5
RNF7
SIAH1
TOPORS
TRAF6
TRAF7
TRIM10
TRIM17
TRIM2
TRIM25
TRIM27
TRIM3
TRIM31
TRIM35
TRIM38
TRIM39
TRIM43
TRIM45
TRIM5
TRIM50
TRIM8
UBE4A
UBOX5
UBTD1
UFM1
UHRF2
XIAP
ZNRF1
ZNRF2
ZNRF4
108 interactors:
ADAMTSL4
AEN
AQP1
ATRIP
BCL6B
BRCA1
BRMS1L
BYSL
C19orf66
CALCOCO2
CBX8
CCDC120
CCDC42
CCHCR1
CEP57L1
CHD2
CTSZ
DCX
DGCR6
DGCR6L
DIEXF
DMRT3
DYDC1
FAM107A
FAM161A
FAM214A
FAM90A1
FARS2
FBF1
FBXL18
FRMD6
GFI1B
GMCL1
GOLGA2
GORASP2
HOXB9
IGBP1
ISCU
JOSD1
KIAA1683
KIF1A
KIFC3
LENG1
LGALS14
LGALS8
MAGOHB
METTL17
MFAP1
MID1
MID1IP1
MOS
MVP
NR1D2
NXF1
OTUB2
PPP1R18
PRPF31
PSMA1
PTCD2
RCOR3
RPH3AL
RPP25L
RUNX1T1
SCNM1
SDCBP
SLC25A48
SLC25A6
SNAI1
SNAP47
SPATA24
SPG21
SPRY2
STX11
SYT17
TCEA2
TCEB3
THAP7
TOP3B
TRIM27
TRIM29
TRIM32
TRIM42
TRIM54
TRPV6
TSGA10
UBE2D1
UBE2D4
UBE2E2
UBE2E3
UBE2U
UBTD1
UNC45A
UTP23
WT1-AS
ZBTB24
ZC2HC1C
ZFYVE21
ZGPAT
ZNF165
ZNF24
ZNF250
ZNF417
ZNF440
ZNF564
ZNF587
ZNF785
ZNF792
ZSCAN12
Entrez ID
51619
11043
HPRD ID
14242
02191
Ensembl ID
ENSG00000078967
Uniprot IDs
Q9Y2X8
Q9UJV3
PDB IDs
2DJA
2DMK
Enriched GO Terms of Interacting Partners
?
Protein Modification By Small Protein Conjugation
Protein Ubiquitination
Cellular Protein Modification Process
Cellular Protein Metabolic Process
Protein Metabolic Process
Protein Polyubiquitination
Protein Autoubiquitination
Cellular Metabolic Process
Ubiquitin-dependent Protein Catabolic Process
Modification-dependent Protein Catabolic Process
Protein Catabolic Process
Proteolysis Involved In Cellular Protein Catabolic Process
Cellular Protein Catabolic Process
Cellular Macromolecule Catabolic Process
Protein K63-linked Ubiquitination
Regulation Of Viral Entry Into Host Cell
Protein K48-linked Ubiquitination
Regulation Of Viral Release From Host Cell
Negative Regulation Of Viral Release From Host Cell
Negative Regulation Of Viral Entry Into Host Cell
Metabolic Process
Negative Regulation Of Viral Process
Catabolic Process
Proteolysis
Protein Ubiquitination Involved In Ubiquitin-dependent Protein Catabolic Process
Positive Regulation Of Sequence-specific DNA Binding Transcription Factor Activity
Regulation Of Viral Process
Protein Monoubiquitination
Positive Regulation Of NF-kappaB Transcription Factor Activity
Regulation Of Sequence-specific DNA Binding Transcription Factor Activity
Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process
Proteasomal Protein Catabolic Process
Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling
Positive Regulation Of Signal Transduction
Negative Regulation Of Viral Transcription
Regulation Of I-kappaB Kinase/NF-kappaB Signaling
Cellular Process
Regulation Of Signal Transduction
Innate Immune Response
Interferon-gamma-mediated Signaling Pathway
Regulation Of Protein Ubiquitination
Cellular Response To Interferon-gamma
Regulation Of Signaling
Positive Regulation Of Intracellular Signal Transduction
Apoptotic Process
Response To Interferon-gamma
Programmed Cell Death
Cell Death
Death
Histone Monoubiquitination
RNA Metabolic Process
Nucleobase-containing Compound Metabolic Process
Cellular Nitrogen Compound Metabolic Process
Gene Expression
Heterocycle Metabolic Process
Cellular Aromatic Compound Metabolic Process
Transcription, DNA-templated
Nitrogen Compound Metabolic Process
RNA Biosynthetic Process
Protein Polyubiquitination
Cellular Macromolecule Biosynthetic Process
Macromolecule Biosynthetic Process
Regulation Of Nitrogen Compound Metabolic Process
Negative Regulation Of RNA Biosynthetic Process
Regulation Of RNA Metabolic Process
Protein K63-linked Ubiquitination
Regulation Of Transcription, DNA-templated
Regulation Of Nucleic Acid-templated Transcription
Regulation Of RNA Biosynthetic Process
Negative Regulation Of Transcription, DNA-templated
Protein K48-linked Ubiquitination
Negative Regulation Of Nucleic Acid-templated Transcription
Biosynthetic Process
Cellular Process
Regulation Of Gene Expression
Negative Regulation Of Gene Expression
Negative Regulation Of Biosynthetic Process
Protein Ubiquitination
Protein Modification By Small Protein Conjugation
Negative Regulation Of Cellular Metabolic Process
Protein K11-linked Ubiquitination
Maturation Of SSU-rRNA From Tricistronic RRNA Transcript (SSU-rRNA, 5.8S RRNA, LSU-rRNA)
Maturation Of SSU-rRNA
Cellular Metabolic Process
Negative Regulation Of Microtubule Depolymerization
Protein K6-linked Ubiquitination
Regulation Of Microtubule-based Process
Ribosomal Small Subunit Biogenesis
Regulation Of Metabolic Process
Negative Regulation Of Transcription From RNA Polymerase II Promoter
Negative Regulation Of Microtubule Polymerization Or Depolymerization
Synaptic Vesicle Fusion To Presynaptic Membrane
Negative Regulation Of Transferase Activity
Regulation Of Transcription From RNA Polymerase II Promoter
Negative Regulation Of Viral Release From Host Cell
Negative Regulation Of Protein Tyrosine Kinase Activity
Regulation Of Microtubule Cytoskeleton Organization
Regulation Of Viral Transcription
Regulation Of Histone H3-K4 Methylation
Regulation Of Microtubule Polymerization Or Depolymerization
Tagcloud
?
accumulation
apoptosis
apoptotic
arsenic
cadmium
conjugating
degradation
downregulation
elevated
enzymes
family
hand
induce
inorganic
mercury
p53
promote
proteasomal
proximal
rat
suppressed
suppression
tubular
ubiquitin
ubiquitination
Tagcloud (Difference)
?
accumulation
apoptosis
apoptotic
arsenic
cadmium
conjugating
degradation
downregulation
elevated
enzymes
family
hand
induce
inorganic
mercury
p53
promote
proteasomal
proximal
rat
suppressed
suppression
tubular
ubiquitin
ubiquitination
Tagcloud (Intersection)
?