UBE2D4 and PJA2

Number of citations of the paper that reports this interaction (PMID 19690564)
33

Data Source:
BioGRID (two hybrid)

		UBE2D4	PJA2
Gene Name		ubiquitin-conjugating enzyme E2D 4 (putative)	praja ring finger 2, E3 ubiquitin protein ligase
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component		Golgi Membrane Cytoplasm Endoplasmic Reticulum Membrane Plasma Membrane Postsynaptic Density Cell Junction Postsynaptic Membrane
	Molecular Function	Ubiquitin-protein Transferase Activity Protein Binding ATP Binding Ligase Activity Ubiquitin Conjugating Enzyme Activity	Ubiquitin-protein Transferase Activity Zinc Ion Binding Ligase Activity Protein Kinase A Catalytic Subunit Binding Protein Kinase A Regulatory Subunit Binding
	Biological Process	Protein Ubiquitination Protein K29-linked Ubiquitination Protein K27-linked Ubiquitination Protein K63-linked Ubiquitination Protein K48-linked Ubiquitination Protein K11-linked Ubiquitination Protein K6-linked Ubiquitination	Long-term Memory Regulation Of Protein Kinase A Signaling Protein Ubiquitination
Pathways		Antigen processing: Ubiquitination & Proteasome degradation Class I MHC mediated antigen processing & presentation Adaptive Immune System	Antigen processing: Ubiquitination & Proteasome degradation Class I MHC mediated antigen processing & presentation Adaptive Immune System
Drugs
Diseases
GWAS
Protein-Protein Interactions		90 interactors: AMFR ARIH2 BFAR BIRC8 CADPS2 CHFR CNOT4 DAZAP2 DTX1 DTX2 DTX3 DTX3L DZIP3 INCA1 LRSAM1 MAGEA11 MAP3K1 MARCH3 MGRN1 MIB1 MID1 MID2 MKRN2 MKRN3 MUL1 MYBL2 MYLIP OTUB1 PHF7 PJA2 RBCK1 RCHY1 RFWD3 RING1 RLIM RMND5B RNF10 RNF103 RNF11 RNF111 RNF114 RNF115 RNF125 RNF126 RNF13 RNF130 RNF138 RNF14 RNF150 RNF165 RNF166 RNF167 RNF181 RNF185 RNF2 RNF25 RNF26 RNF38 RNF4 RNF43 RNF5 RNF7 SIAH1 TOPORS TRAF6 TRAF7 TRIM10 TRIM17 TRIM2 TRIM25 TRIM27 TRIM3 TRIM31 TRIM35 TRIM38 TRIM39 TRIM43 TRIM45 TRIM5 TRIM50 TRIM8 UBE4A UBOX5 UBTD1 UFM1 UHRF2 XIAP ZNRF1 ZNRF2 ZNRF4	12 interactors: MAGED1 PRKAR1A PRKAR2A UBC UBE2D1 UBE2D2 UBE2D3 UBE2D4 UBE2J1 UBE2L6 UBE2N UBE2W
Entrez ID		51619	9867
HPRD ID		14242	11436
Ensembl ID		ENSG00000078967	ENSG00000198961
Uniprot IDs		Q9Y2X8	O43164
PDB IDs
Enriched GO Terms of Interacting Partners?		Protein Modification By Small Protein Conjugation Protein Ubiquitination Cellular Protein Modification Process Cellular Protein Metabolic Process Protein Metabolic Process Protein Polyubiquitination Protein Autoubiquitination Cellular Metabolic Process Ubiquitin-dependent Protein Catabolic Process Modification-dependent Protein Catabolic Process Protein Catabolic Process Proteolysis Involved In Cellular Protein Catabolic Process Cellular Protein Catabolic Process Cellular Macromolecule Catabolic Process Protein K63-linked Ubiquitination Regulation Of Viral Entry Into Host Cell Protein K48-linked Ubiquitination Regulation Of Viral Release From Host Cell Negative Regulation Of Viral Release From Host Cell Negative Regulation Of Viral Entry Into Host Cell Metabolic Process Negative Regulation Of Viral Process Catabolic Process Proteolysis Protein Ubiquitination Involved In Ubiquitin-dependent Protein Catabolic Process Positive Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Regulation Of Viral Process Protein Monoubiquitination Positive Regulation Of NF-kappaB Transcription Factor Activity Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Proteasomal Protein Catabolic Process Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling Positive Regulation Of Signal Transduction Negative Regulation Of Viral Transcription Regulation Of I-kappaB Kinase/NF-kappaB Signaling Cellular Process Regulation Of Signal Transduction Innate Immune Response Interferon-gamma-mediated Signaling Pathway Regulation Of Protein Ubiquitination Cellular Response To Interferon-gamma Regulation Of Signaling Positive Regulation Of Intracellular Signal Transduction Apoptotic Process Response To Interferon-gamma Programmed Cell Death Cell Death Death Histone Monoubiquitination	Protein Ubiquitination Protein Polyubiquitination Protein Modification By Small Protein Conjugation Modification-dependent Protein Catabolic Process Proteolysis Involved In Cellular Protein Catabolic Process Cellular Protein Catabolic Process Protein Catabolic Process Toll-like Receptor 4 Signaling Pathway Regulation Of Transcription From RNA Polymerase II Promoter In Response To Hypoxia Innate Immune Response Cellular Macromolecule Catabolic Process Ubiquitin-dependent Protein Catabolic Process Toll-like Receptor Signaling Pathway Protein K48-linked Ubiquitination Pattern Recognition Receptor Signaling Pathway Innate Immune Response-activating Signal Transduction Activation Of Innate Immune Response Regulation Of Transcription From RNA Polymerase II Promoter In Response To Stress Regulation Of DNA-templated Transcription In Response To Stress Positive Regulation Of Innate Immune Response Cellular Response To Organic Substance TRIF-dependent Toll-like Receptor Signaling Pathway MyD88-independent Toll-like Receptor Signaling Pathway Toll-like Receptor 3 Signaling Pathway Immune Response Defense Response Regulation Of Innate Immune Response Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Proteasomal Protein Catabolic Process Proteolysis Cellular Response To Hypoxia Positive Regulation Of Transferase Activity Cellular Response To Decreased Oxygen Levels Protein K11-linked Ubiquitination Cellular Response To Growth Factor Stimulus Response To Growth Factor Cellular Response To Oxygen Levels Response To Organic Substance Catabolic Process Negative Regulation Of Type I Interferon Production Immune System Process Immune Response-regulating Signaling Pathway Enzyme Linked Receptor Protein Signaling Pathway Positive Regulation Of Protein Modification Process Cellular Protein Modification Process Neurotrophin TRK Receptor Signaling Pathway Neurotrophin Signaling Pathway Response To Stress Negative Regulation Of CAMP-dependent Protein Kinase Activity Positive Regulation Of Ubiquitin-protein Transferase Activity
Tagcloud ?		accumulation apoptosis apoptotic arsenic cadmium conjugating degradation downregulation elevated enzymes family hand induce inorganic mercury p53 promote proteasomal proximal rat suppressed suppression tubular ubiquitin ubiquitination	akap akap149 akaps camp complementary crc dependence destabilization e3 enzymatic exploiting fate generates igf1r ligase manipulation mechanistic opposing opposite organized osi pka praja2 respect subset survivin tgfbeta utilize xiap
Tagcloud (Difference) ?		accumulation apoptosis apoptotic arsenic cadmium conjugating degradation downregulation elevated enzymes family hand induce inorganic mercury p53 promote proteasomal proximal rat suppressed suppression tubular ubiquitin ubiquitination	akap akap149 akaps camp complementary crc dependence destabilization e3 enzymatic exploiting fate generates igf1r ligase manipulation mechanistic opposing opposite organized osi pka praja2 respect subset survivin tgfbeta utilize xiap
Tagcloud (Intersection) ?