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NCKIPSD and SORBS3
Number of citations of the paper that reports this interaction (PMID
25416956
)
0
Data Source:
BioGRID
(two hybrid)
NCKIPSD
SORBS3
Gene Name
NCK interacting protein with SH3 domain
sorbin and SH3 domain containing 3
Image
No pdb structure
Gene Ontology Annotations
Cellular Component
Cytosol
Intermediate Filament
COP9 Signalosome
Nucleus
Cytosol
Cytoskeleton
Focal Adhesion
Molecular Function
Protein Binding
Cytoskeletal Protein Binding
SH3 Domain Binding
Structural Constituent Of Cytoskeleton
Protein Binding
Transcription Factor Binding
Vinculin Binding
Biological Process
NLS-bearing Protein Import Into Nucleus
Cytoskeleton Organization
Signal Transduction
Fc-gamma Receptor Signaling Pathway Involved In Phagocytosis
Innate Immune Response
Negative Regulation Of Transcription From RNA Polymerase II Promoter
Muscle Contraction
Actin Filament Organization
Cell Adhesion
Cell-substrate Adhesion
Positive Regulation Of MAPK Cascade
Positive Regulation Of Cytoskeleton Organization
Positive Regulation Of Stress Fiber Assembly
Pathways
Fcgamma receptor (FCGR) dependent phagocytosis
Regulation of actin dynamics for phagocytic cup formation
Innate Immune System
Smooth Muscle Contraction
Drugs
Diseases
GWAS
HIV-1 control (
20205591
)
Protein-Protein Interactions
19 interactors:
ARHGEF7
BAIAP2
DIAPH2
DIAPH3
DLG4
DMRTB1
FASLG
GRB2
ITGB1
KHDRBS1
MAPK3
NCK1
NCK2
PSMD9
SORBS3
STAC
WAS
WASL
YWHAG
46 interactors:
ABL1
ADAM15
ADAMTSL4
AKT1
ARNT2
CBLB
CPNE2
CPSF7
DDX17
DIP2A
DLG5
DMRTB1
DVL2
EFS
EIF3H
FAM154A
FASLG
FLOT1
HNRNPK
HNRNPUL1
INPPL1
KIAA0408
KIAA1217
MAPK1
MAPK3
NCKIPSD
NOTCH3
PAK1
PAK2
PAK7
RBMX
SAFB2
SH2D4A
SOCS7
SRCIN1
TBC1D22B
TRIM23
TRIM27
TRIM41
VARS2
VPS37B
VPS37C
ZBED1
ZBTB25
ZBTB7B
ZC4H2
Entrez ID
51517
10174
HPRD ID
09450
11535
Ensembl ID
ENSG00000213672
ENSG00000120896
Uniprot IDs
Q9NZQ3
O60504
PDB IDs
2CT3
2DLM
2NWM
2YUP
Enriched GO Terms of Interacting Partners
?
Actin Cytoskeleton Organization
Actin Filament-based Process
Axonogenesis
Axon Development
Cell Morphogenesis Involved In Neuron Differentiation
Axon Guidance
Positive Regulation Of Organelle Organization
Neuron Projection Morphogenesis
Cell Morphogenesis Involved In Differentiation
Actin Filament Organization
Regulation Of Cytoskeleton Organization
Fc-gamma Receptor Signaling Pathway Involved In Phagocytosis
Fc-gamma Receptor Signaling Pathway
Fc Receptor Mediated Stimulatory Signaling Pathway
Regulation Of Cellular Component Organization
Cytoskeleton Organization
Neuron Projection Development
Cell Projection Morphogenesis
Regulation Of Actin Cytoskeleton Organization
Cell Part Morphogenesis
Positive Regulation Of Cytoskeleton Organization
Chemotaxis
Positive Regulation Of Signal Transduction
Regulation Of Organelle Organization
Regulation Of Actin Filament-based Process
Neuron Development
Cell Development
Cellular Component Assembly
Regulation Of Signaling
Cell Morphogenesis
Phagocytosis
Fc Receptor Signaling Pathway
Neuron Differentiation
Immune Response-activating Cell Surface Receptor Signaling Pathway
Generation Of Neurons
Cell Projection Organization
Neurogenesis
Immune System Process
Regulation Of Signal Transduction
Signal Transduction
Response To External Stimulus
Immune Response-regulating Cell Surface Receptor Signaling Pathway
Regulation Of Epidermal Growth Factor Receptor Signaling Pathway
Endocytosis
Regulation Of ERBB Signaling Pathway
Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway
Organelle Organization
Protein Complex Assembly
Signaling
Regulation Of Endoplasmic Reticulum Stress-induced EIF2 Alpha Phosphorylation
Gene Expression
Regulation Of Cellular Amino Acid Metabolic Process
Transcription, DNA-templated
Regulation Of Cellular Ketone Metabolic Process
Cellular Macromolecule Biosynthetic Process
Macromolecule Biosynthetic Process
RNA Biosynthetic Process
Regulation Of Metabolic Process
Fc Receptor Signaling Pathway
Regulation Of Protein Kinase Activity
Regulation Of Kinase Activity
Vascular Endothelial Growth Factor Receptor Signaling Pathway
Positive Regulation Of Protein Metabolic Process
Regulation Of Cellular Process
Negative Regulation Of Protein Kinase Activity
Intracellular Signal Transduction
Negative Regulation Of Kinase Activity
Regulation Of Protein Metabolic Process
Immune Response-regulating Cell Surface Receptor Signaling Pathway
RNA Metabolic Process
Regulation Of Protein Tyrosine Kinase Activity
Biosynthetic Process
Regulation Of Gene Expression
Fc-gamma Receptor Signaling Pathway Involved In Phagocytosis
Fc-gamma Receptor Signaling Pathway
Fc Receptor Mediated Stimulatory Signaling Pathway
Immune Response-activating Cell Surface Receptor Signaling Pathway
Innate Immune Response
Response To Insulin
Immune Response
Regulation Of Protein Phosphorylation
Negative Regulation Of Transferase Activity
Response To Epidermal Growth Factor
Immune Response-regulating Signaling Pathway
Positive Regulation Of Protein Kinase Activity
Regulation Of Golgi Inheritance
Negative Regulation Of Protein Phosphorylation
Regulation Of Stress-activated MAPK Cascade
Positive Regulation Of Cellular Protein Metabolic Process
Positive Regulation Of Kinase Activity
Regulation Of Cellular Protein Metabolic Process
Caveolin-mediated Endocytosis
Cellular Response To Insulin Stimulus
Cell Morphogenesis Involved In Differentiation
Protein Autophosphorylation
Positive Regulation Of Protein Phosphorylation
Regulation Of Peptidyl-tyrosine Phosphorylation
Positive Regulation Of Protein Tyrosine Kinase Activity
Regulation Of Nitrogen Compound Metabolic Process
Regulation Of Phosphorus Metabolic Process
Tagcloud
?
2d
3d
4ebp1
adenocarcinomas
atr
atrip
clearer
concordant
discordant
egr
emphasized
gliomas
growths
gsk3alphabeta
hypoxia
look
mek1
monolayer
nfkappabetap65
normoxia
phosphoprotein
reflective
s6
ser235
ser240
ser423
ser65
smad3
vegfr2
Tagcloud (Difference)
?
2d
3d
4ebp1
adenocarcinomas
atr
atrip
clearer
concordant
discordant
egr
emphasized
gliomas
growths
gsk3alphabeta
hypoxia
look
mek1
monolayer
nfkappabetap65
normoxia
phosphoprotein
reflective
s6
ser235
ser240
ser423
ser65
smad3
vegfr2
Tagcloud (Intersection)
?