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NCKIPSD and WAS
Number of citations of the paper that reports this interaction (PMID
14559906
)
6
Data Source:
HPRD
(in vitro, in vivo)
NCKIPSD
WAS
Gene Name
NCK interacting protein with SH3 domain
Wiskott-Aldrich syndrome
Image
No pdb structure
Gene Ontology Annotations
Cellular Component
Cytosol
Intermediate Filament
COP9 Signalosome
Cytosol
Cell-cell Junction
Vesicle Membrane
Actin Cytoskeleton
Extracellular Vesicular Exosome
Molecular Function
Protein Binding
Cytoskeletal Protein Binding
SH3 Domain Binding
Actin Binding
Small GTPase Regulator Activity
Protein Binding
SH3 Domain Binding
Protein Kinase Binding
Identical Protein Binding
Phospholipase Binding
Biological Process
NLS-bearing Protein Import Into Nucleus
Cytoskeleton Organization
Signal Transduction
Fc-gamma Receptor Signaling Pathway Involved In Phagocytosis
Innate Immune Response
Protein Complex Assembly
Defense Response
Immune Response
Blood Coagulation
Actin Polymerization Or Depolymerization
Epidermis Development
Endosomal Transport
Actin Filament Polymerization
Actin Filament-based Movement
Fc-gamma Receptor Signaling Pathway Involved In Phagocytosis
T Cell Activation
Innate Immune Response
Regulation Of Catalytic Activity
T Cell Receptor Signaling Pathway
Positive Regulation Of Arp2/3 Complex-mediated Actin Nucleation
Pathways
Fcgamma receptor (FCGR) dependent phagocytosis
Regulation of actin dynamics for phagocytic cup formation
Innate Immune System
TCR signaling
Generation of second messenger molecules
Fcgamma receptor (FCGR) dependent phagocytosis
Regulation of actin dynamics for phagocytic cup formation
Innate Immune System
Adaptive Immune System
Drugs
Diseases
GWAS
Protein-Protein Interactions
19 interactors:
ARHGEF7
BAIAP2
DIAPH2
DIAPH3
DLG4
DMRTB1
FASLG
GRB2
ITGB1
KHDRBS1
MAPK3
NCK1
NCK2
PSMD9
SORBS3
STAC
WAS
WASL
YWHAG
53 interactors:
ABI3
ACTC1
APBB1
APPBP2
ARHGAP1
ARHGEF7
ARPC1B
ARPC2
ARPC3
BAIAP2L1
BTK
C5AR1
CDC42
CIB1
CRKL
CSNK2A1
CSNK2A2
DLG1
ENAH
EVL
FCHSD2
FGR
FYB
FYN
GAS7
GRB2
HCK
HCLS1
ITK
ITSN2
LCK
LCP2
NCK1
NCK2
NCKIPSD
PIK3R1
PLCG1
PRPF40A
PSTPIP1
PTPN12
RAC1
RGS14
RHOJ
SORBS2
SRC
TCERG1
TEC
TNK2
TRIP10
VASP
WBP4
WIPF1
WIPF2
Entrez ID
51517
7454
HPRD ID
09450
02314
Ensembl ID
ENSG00000213672
ENSG00000015285
Uniprot IDs
Q9NZQ3
P42768
PDB IDs
1CEE
1EJ5
1T84
2A3Z
2K42
2OT0
Enriched GO Terms of Interacting Partners
?
Actin Cytoskeleton Organization
Actin Filament-based Process
Axonogenesis
Axon Development
Cell Morphogenesis Involved In Neuron Differentiation
Axon Guidance
Positive Regulation Of Organelle Organization
Neuron Projection Morphogenesis
Cell Morphogenesis Involved In Differentiation
Actin Filament Organization
Regulation Of Cytoskeleton Organization
Fc-gamma Receptor Signaling Pathway Involved In Phagocytosis
Fc-gamma Receptor Signaling Pathway
Fc Receptor Mediated Stimulatory Signaling Pathway
Regulation Of Cellular Component Organization
Cytoskeleton Organization
Neuron Projection Development
Cell Projection Morphogenesis
Regulation Of Actin Cytoskeleton Organization
Cell Part Morphogenesis
Positive Regulation Of Cytoskeleton Organization
Chemotaxis
Positive Regulation Of Signal Transduction
Regulation Of Organelle Organization
Regulation Of Actin Filament-based Process
Neuron Development
Cell Development
Cellular Component Assembly
Regulation Of Signaling
Cell Morphogenesis
Phagocytosis
Fc Receptor Signaling Pathway
Neuron Differentiation
Immune Response-activating Cell Surface Receptor Signaling Pathway
Generation Of Neurons
Cell Projection Organization
Neurogenesis
Immune System Process
Regulation Of Signal Transduction
Signal Transduction
Response To External Stimulus
Immune Response-regulating Cell Surface Receptor Signaling Pathway
Regulation Of Epidermal Growth Factor Receptor Signaling Pathway
Endocytosis
Regulation Of ERBB Signaling Pathway
Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway
Organelle Organization
Protein Complex Assembly
Signaling
Regulation Of Endoplasmic Reticulum Stress-induced EIF2 Alpha Phosphorylation
Immune Response-activating Cell Surface Receptor Signaling Pathway
Immune Response-regulating Cell Surface Receptor Signaling Pathway
Immune Response-regulating Signaling Pathway
Fc Receptor Signaling Pathway
Movement Of Cell Or Subcellular Component
Positive Regulation Of Immune Response
Positive Regulation Of Immune System Process
Regulation Of Immune System Process
Locomotion
Axon Guidance
Regulation Of Immune Response
Fc-gamma Receptor Signaling Pathway Involved In Phagocytosis
Fc-gamma Receptor Signaling Pathway
Fc Receptor Mediated Stimulatory Signaling Pathway
Immune System Process
Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway
Actin Filament Organization
Innate Immune Response
Chemotaxis
Positive Regulation Of Actin Filament Polymerization
Axonogenesis
Neuron Projection Morphogenesis
Immune Response
Positive Regulation Of Protein Polymerization
Enzyme Linked Receptor Protein Signaling Pathway
Axon Development
Actin Cytoskeleton Organization
Cell Morphogenesis Involved In Neuron Differentiation
Phagocytosis
Positive Regulation Of Protein Complex Assembly
Cell Morphogenesis Involved In Differentiation
Cytoskeleton Organization
Actin Filament-based Process
Regulation Of Actin Filament Polymerization
Cell Surface Receptor Signaling Pathway
Endocytosis
Peptidyl-tyrosine Autophosphorylation
Positive Regulation Of Cytoskeleton Organization
Regulation Of Actin Polymerization Or Depolymerization
Regulation Of Protein Complex Assembly
Regulation Of Actin Filament Length
Neuron Projection Development
Regulation Of Cellular Component Organization
Antigen Receptor-mediated Signaling Pathway
Cell Projection Morphogenesis
Cell Part Morphogenesis
Response To External Stimulus
Signal Transduction
T Cell Receptor Signaling Pathway
Signaling
Tagcloud
?
2d
3d
4ebp1
adenocarcinomas
atr
atrip
clearer
concordant
discordant
egr
emphasized
gliomas
growths
gsk3alphabeta
hypoxia
look
mek1
monolayer
nfkappabetap65
normoxia
phosphoprotein
reflective
s6
ser235
ser240
ser423
ser65
smad3
vegfr2
Tagcloud (Difference)
?
2d
3d
4ebp1
adenocarcinomas
atr
atrip
clearer
concordant
discordant
egr
emphasized
gliomas
growths
gsk3alphabeta
hypoxia
look
mek1
monolayer
nfkappabetap65
normoxia
phosphoprotein
reflective
s6
ser235
ser240
ser423
ser65
smad3
vegfr2
Tagcloud (Intersection)
?