NCKIPSD and DMRTB1

Number of citations of the paper that reports this interaction (PMID 16189514)
699

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		NCKIPSD	DMRTB1
Gene Name		NCK interacting protein with SH3 domain	DMRT-like family B with proline-rich C-terminal, 1
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Cytosol Intermediate Filament COP9 Signalosome	Nucleus
	Molecular Function	Protein Binding Cytoskeletal Protein Binding SH3 Domain Binding	Core Promoter Proximal Region Sequence-specific DNA Binding Sequence-specific DNA Binding Transcription Factor Activity Protein Homodimerization Activity Metal Ion Binding
	Biological Process	NLS-bearing Protein Import Into Nucleus Cytoskeleton Organization Signal Transduction Fc-gamma Receptor Signaling Pathway Involved In Phagocytosis Innate Immune Response	Transcription, DNA-templated Regulation Of Transcription, DNA-templated Sex Differentiation
Pathways		Fcgamma receptor (FCGR) dependent phagocytosis Regulation of actin dynamics for phagocytic cup formation Innate Immune System
Drugs
Diseases
GWAS			Response to statin therapy ( 20339536)
Protein-Protein Interactions		19 interactors: ARHGEF7 BAIAP2 DIAPH2 DIAPH3 DLG4 DMRTB1 FASLG GRB2 ITGB1 KHDRBS1 MAPK3 NCK1 NCK2 PSMD9 SORBS3 STAC WAS WASL YWHAG	13 interactors: CTBP1 CTBP2 EWSR1 EYA2 IL16 LENG8 NCKIPSD NIF3L1 PRMT2 RBFOX1 RBFOX2 SORBS3 VASP
Entrez ID		51517	63948
HPRD ID		09450	16828
Ensembl ID		ENSG00000213672	ENSG00000143006
Uniprot IDs		Q9NZQ3	Q96MA1
PDB IDs
Enriched GO Terms of Interacting Partners?		Actin Cytoskeleton Organization Actin Filament-based Process Axonogenesis Axon Development Cell Morphogenesis Involved In Neuron Differentiation Axon Guidance Positive Regulation Of Organelle Organization Neuron Projection Morphogenesis Cell Morphogenesis Involved In Differentiation Actin Filament Organization Regulation Of Cytoskeleton Organization Fc-gamma Receptor Signaling Pathway Involved In Phagocytosis Fc-gamma Receptor Signaling Pathway Fc Receptor Mediated Stimulatory Signaling Pathway Regulation Of Cellular Component Organization Cytoskeleton Organization Neuron Projection Development Cell Projection Morphogenesis Regulation Of Actin Cytoskeleton Organization Cell Part Morphogenesis Positive Regulation Of Cytoskeleton Organization Chemotaxis Positive Regulation Of Signal Transduction Regulation Of Organelle Organization Regulation Of Actin Filament-based Process Neuron Development Cell Development Cellular Component Assembly Regulation Of Signaling Cell Morphogenesis Phagocytosis Fc Receptor Signaling Pathway Neuron Differentiation Immune Response-activating Cell Surface Receptor Signaling Pathway Generation Of Neurons Cell Projection Organization Neurogenesis Immune System Process Regulation Of Signal Transduction Signal Transduction Response To External Stimulus Immune Response-regulating Cell Surface Receptor Signaling Pathway Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Endocytosis Regulation Of ERBB Signaling Pathway Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Organelle Organization Protein Complex Assembly Signaling Regulation Of Endoplasmic Reticulum Stress-induced EIF2 Alpha Phosphorylation	Regulation Of RNA Metabolic Process Regulation Of Gene Expression Regulation Of Nitrogen Compound Metabolic Process Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process White Fat Cell Differentiation Viral Genome Replication Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Regulation Of Cellular Process Negative Regulation Of Gene Expression Negative Regulation Of Biosynthetic Process Regulation Of Metabolic Process RNA Metabolic Process Negative Regulation Of Transcription From RNA Polymerase II Promoter By Histone Modification Gene Expression Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Neuromuscular Process Controlling Balance Cellular Nitrogen Compound Metabolic Process Histone Modification Positive Regulation Of Organelle Organization 7,8-dihydroneopterin 3'-triphosphate Biosynthetic Process Regulation Of RNA Splicing Dihydrobiopterin Metabolic Process Nitrogen Compound Metabolic Process Fat Cell Differentiation Neuromuscular Process Viral Process Organelle Organization Negative Regulation Of Cellular Metabolic Process Radial Glia Guided Migration Of Purkinje Cell Regulation Of Definitive Erythrocyte Differentiation Positive Regulation Of Retinoic Acid Receptor Signaling Pathway Histone Dephosphorylation Positive Regulation Of Chromatin Binding Chromatin Modification Nucleobase-containing Compound Metabolic Process Mesodermal Cell Fate Specification Cell Differentiation Transcription, DNA-templated Viral Life Cycle RNA Biosynthetic Process Positive Regulation Of Cytoskeleton Organization Negative Regulation Of Histone H4 Acetylation Chromatin Organization Mitochondrial Outer Membrane Permeabilization Peptidyl-arginine Methylation, To Asymmetrical-dimethyl Arginine
Tagcloud ?		2d 3d 4ebp1 adenocarcinomas atr atrip clearer concordant discordant egr emphasized gliomas growths gsk3alphabeta hypoxia look mek1 monolayer nfkappabetap65 normoxia phosphoprotein reflective s6 ser235 ser240 ser423 ser65 smad3 vegfr2
Tagcloud (Difference) ?		2d 3d 4ebp1 adenocarcinomas atr atrip clearer concordant discordant egr emphasized gliomas growths gsk3alphabeta hypoxia look mek1 monolayer nfkappabetap65 normoxia phosphoprotein reflective s6 ser235 ser240 ser423 ser65 smad3 vegfr2
Tagcloud (Intersection) ?