KLHL5 and MAP1LC3B

Number of citations of the paper that reports this interaction (PMID 21900206)
27

Data Source:
BioGRID (two hybrid)

		KLHL5	MAP1LC3B
Gene Name		kelch-like family member 5	microtubule-associated protein 1 light chain 3 beta
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Cytoplasm Cytoskeleton	Pre-autophagosomal Structure Autophagic Vacuole Membrane Intracellular Autophagic Vacuole Cytosol Microtubule Axoneme Endomembrane System Extrinsic Component Of Membrane Organelle Membrane Cytoplasmic Vesicle
	Molecular Function	Molecular_function Actin Binding	Protein Binding Microtubule Binding GABA Receptor Binding
	Biological Process	Biological_process	Autophagic Vacuole Assembly Mitochondrion Degradation Cellular Response To Nitrogen Starvation Nucleophagy Membrane Fusion
Pathways
Drugs
Diseases
GWAS			Major depressive disorder ( 22472876)
Protein-Protein Interactions		5 interactors: CUL3 GABARAPL2 MAP1LC3B SMN1 TK1	50 interactors: AAMP ADD1 ADNP ARFGAP1 ATG3 ATG4A ATG4B ATG7 BNIP3 BRD3 CASP8 CCSER2 CLTA DBI DBN1 DNMT3B EED EPS8 FAM134A FAM65A FUNDC1 FYCO1 GABARAPL2 GORASP2 KBTBD7 KLHL5 KXD1 LUC7L2 MKRN1 MRFAP1 MYBL2 NHP2L1 RAD1 RAP1GAP RPLP1 SAFB SHFM1 SMARCB1 SPAG9 SQSTM1 TAF7 TAX1BP1 TBC1D17 TBC1D25 TBC1D9 TBC1D9B THAP7 TMOD3 TNIP1 UPF2
Entrez ID		51088	81631
HPRD ID		10477	14358
Ensembl ID		ENSG00000109790	ENSG00000140941
Uniprot IDs		Q59HD9 Q7Z6D5 Q96PQ7	H6UMI0 Q658J6 Q9GZQ8
PDB IDs			1V49 2LUE 2ZJD 3VTU 3VTV 3VTW
Enriched GO Terms of Interacting Partners?		Cellular Component Assembly Cellular Response To Nitrogen Starvation Nucleophagy Mitochondrion Degradation Organelle Disassembly Autophagic Vacuole Assembly Macroautophagy Response To Nutrient Levels Response To Extracellular Stimulus Vacuole Organization Fetal Process Involved In Parturition Membrane Fusion Cellular Response To Starvation Skeletal Muscle Cell Proliferation Membrane Organization Autophagy Cellular Response To Nutrient Levels Response To Starvation Trophectodermal Cellular Morphogenesis Regulation Of Proteasomal Protein Catabolic Process Cellular Response To Extracellular Stimulus Negative Regulation Of Cyclin-dependent Protein Serine/threonine Kinase By Cyclin Degradation Response To Cortisol Thymidine Metabolic Process Golgi Vesicle Transport Positive Regulation Of Mitotic Metaphase/anaphase Transition Deoxyribonucleoside Monophosphate Biosynthetic Process Pyrimidine Nucleoside Salvage Pyrimidine-containing Compound Salvage Regulation Of Protein Catabolic Process Embryonic Cleavage Mitochondrion Organization Stress Fiber Assembly Positive Regulation Of Chromosome Segregation Catabolic Process Parturition Organelle Assembly Response To External Stimulus COPII Vesicle Coating COPII-coated Vesicle Budding Response To Copper Ion Negative Regulation Of Rho Protein Signal Transduction Trophectodermal Cell Differentiation Mitotic Metaphase Plate Congression Negative Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity Vesicle Targeting, To, From Or Within Golgi Positive Regulation Of ATPase Activity Metaphase Plate Congression Regulation Of Proteolysis Pyrimidine Nucleobase Metabolic Process	Autophagy Mitochondrion Degradation Organelle Disassembly Nucleophagy Cellular Response To Nitrogen Starvation Macroautophagy Regulation Of Organelle Organization Cellular Response To Starvation Positive Regulation Of Metabolic Process Organelle Organization Positive Regulation Of Autophagy Response To Starvation Cellular Response To Nutrient Levels Autophagic Vacuole Assembly Cellular Response To Extracellular Stimulus Cellular Response To Stress Intracellular Transport Catabolic Process Mitochondrion Organization Regulation Of Cellular Component Organization C-terminal Protein Lipidation Protein Delipidation Membrane Organization Response To Stress Vacuole Organization Regulation Of Autophagy Positive Regulation Of Cellular Metabolic Process Regulation Of Protein Complex Disassembly Establishment Of Localization In Cell Regulation Of Histone Modification Actin Filament Capping Positive Regulation Of Rab GTPase Activity Regulation Of Rab GTPase Activity Regulation Of Rab Protein Signal Transduction Mitochondrial Fragmentation Involved In Apoptotic Process Positive Regulation Of Hydrolase Activity Cellular Localization Negative Regulation Of Actin Filament Depolymerization Response To Nutrient Levels Cellular Component Assembly Protein Localization Regulation Of Ras Protein Signal Transduction Response To Extracellular Stimulus Response To Cobalt Ion Protein Targeting To Membrane Regulation Of Actin Filament Depolymerization Organelle Assembly Negative Regulation Of Actin Filament Polymerization Positive Regulation Of Macroautophagy Negative Regulation Of Histone Acetylation
Tagcloud ?			akt1 antipsychotic atg atg12 atg4b atg5 atg7 autophagic autophagosome autophagosomes autophagy bak1 bcl2l11 becn1 cdkn1a cdkn1b chloroquine colocalization dysfunctional gabarap henceforth olanzapine overtly pmaip1 sqstm1 sy5y trp53 unmask
Tagcloud (Difference) ?			akt1 antipsychotic atg atg12 atg4b atg5 atg7 autophagic autophagosome autophagosomes autophagy bak1 bcl2l11 becn1 cdkn1a cdkn1b chloroquine colocalization dysfunctional gabarap henceforth olanzapine overtly pmaip1 sqstm1 sy5y trp53 unmask
Tagcloud (Intersection) ?