KLHL5

Description		kelch like family member 5
Image		No pdb structure
GO Annotations	Cellular Component	Cytoplasm Cytosol Cytoskeleton Plasma Membrane Microtubule Cytoskeleton Cul3-RING Ubiquitin Ligase Complex
	Molecular Function	Actin Binding Protein Binding Ubiquitin-like Ligase-substrate Adaptor Activity
	Biological Process	Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process
Pathways		Neddylation Antigen processing: Ubiquitination & Proteasome degradation
Drugs
Diseases
GWAS		Asthma (childhood onset) ( 23829686)
Interacting Genes		6 interacting genes: GABARAPL2 MAP1LC3B MTNR1A SMN1 TK1 USP7
Entrez ID		51088
HPRD ID		10477
Ensembl ID		ENSG00000109790
Uniprot IDs		A0A804C9D6 Q59HD9 Q7Z6D5 Q96PQ7
PDB IDs
Enriched GO Terms of Interacting Partners?		Autophagosome Organization Autophagosome Assembly Cellular Response To Nitrogen Starvation Phosphatidylethanolamine Binding Vacuole Organization Cellular Response To Nutrient Levels Autophagosome Maturation Autophagosome Membrane Mitophagy Negative Regulation Of Proteasomal Protein Catabolic Process Cellular Component Assembly Autophagy Of Mitochondrion Negative Regulation Of Proteolysis Involved In Protein Catabolic Process Autophagosome Response To Nutrient Levels Protein-containing Complex Organization Thymidine Kinase Activity Negative Regulation Of Protein Catabolic Process Phospholipid Binding DNA Synthesis Involved In Mitotic DNA Replication Negative Regulation Of Proteolysis Symbiont-mediated Disruption Of Host Cell PML Body Protein-containing Complex Disassembly Melatonin Receptor Activity Organelle Assembly Macroautophagy Thymidine Biosynthetic Process Cellular Response To Starvation Regulation Of Proteasomal Protein Catabolic Process Thymidine Metabolic Process Regulation Of Establishment Of Protein Localization To Chromosome Regulation Of Establishment Of Protein Localization To Telomere Regulation Of Retrograde Transport, Endosome To Golgi Response To Starvation Rhythmic Process Deoxyribonucleoside Monophosphate Biosynthetic Process Monoubiquitinated Protein Deubiquitination Microtubule Binding Ceramide Binding SMN Complex DNA Alkylation Repair Gemini Of Cajal Bodies Pyrimidine Nucleoside Metabolic Process Transcription-coupled Nucleotide-excision Repair Autophagy Ubiquitin Protein Ligase Binding Regulation Of Telomere Capping Negative Regulation Of Gene Expression Via Chromosomal CpG Island Methylation Hormone Binding SMN-Sm Protein Complex
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