PBX3 and MEIS1

Number of citations of the paper that reports this interaction (PMID 15466398)
22

Data Source:
HPRD (in vitro)

		PBX3	MEIS1
Gene Name		pre-B-cell leukemia homeobox 3	Meis homeobox 1
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Transcription Factor Complex	Nucleus Transcription Factor Complex
	Molecular Function	Sequence-specific DNA Binding Transcription Factor Activity Sequence-specific DNA Binding	RNA Polymerase II Core Promoter Proximal Region Sequence-specific DNA Binding RNA Polymerase II Core Promoter Proximal Region Sequence-specific DNA Binding Transcription Factor Activity Involved In Positive Regulation Of Transcription Chromatin Binding RNA Polymerase II Distal Enhancer Sequence-specific DNA Binding Transcription Factor Activity Protein Binding Protein Heterodimerization Activity
	Biological Process	Regulation Of Respiratory Gaseous Exchange By Neurological System Process Transcription, DNA-templated Regulation Of Transcription, DNA-templated Anterior Compartment Pattern Formation Posterior Compartment Specification Respiratory Gaseous Exchange Adult Locomotory Behavior Dorsal Spinal Cord Development Neuron Development	Angiogenesis Lens Morphogenesis In Camera-type Eye Transcription From RNA Polymerase II Promoter Megakaryocyte Development Negative Regulation Of Myeloid Cell Differentiation Negative Regulation Of Neuron Differentiation Positive Regulation Of Transcription From RNA Polymerase II Promoter Definitive Hemopoiesis
Pathways
Drugs
Diseases
GWAS			PR interval ( 20062060 23139255) Restless legs syndrome ( 17637780 21779176)
Protein-Protein Interactions		14 interactors: AGTRAP ARL6IP1 FSD2 HOXA9 HOXB8 MAGEA1 MAGEC2 MAL2 MEIS1 RABAC1 TPM3 TRAF1 TRIM44 ZNHIT3	27 interactors: EMX2 ETS1 HOXA10 HOXA11 HOXA13 HOXA2 HOXA5 HOXA7 HOXA9 HOXB1 HOXB13 HOXB4 HOXB8 HOXC11 HOXC13 HOXD11 HOXD12 HOXD13 HOXD4 HOXD9 PBX1 PBX3 PKNOX1 TLX1 TLX2 TLX3 TRMT10B
Entrez ID		5090	4211
HPRD ID		15938	03442
Ensembl ID		ENSG00000167081	ENSG00000143995
Uniprot IDs		P40426 Q96AL5	F5GYS8 F8W8U3 O00470
PDB IDs
Enriched GO Terms of Interacting Partners?		Negative Regulation Of Myeloid Cell Differentiation Definitive Hemopoiesis Regulation Of Myeloid Cell Differentiation Negative Regulation Of Immune System Process Skeletal System Development	Anterior/posterior Pattern Specification Pattern Specification Process Embryonic Morphogenesis Transcription, DNA-templated Skeletal System Development Embryonic Skeletal System Development RNA Biosynthetic Process Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Anatomical Structure Morphogenesis Multicellular Organismal Development System Development Regulation Of Gene Expression Regulation Of Nitrogen Compound Metabolic Process Embryonic Skeletal System Morphogenesis RNA Metabolic Process Limb Development Embryo Development Gene Expression Organ Development Developmental Process Organ Morphogenesis Embryonic Limb Morphogenesis Cellular Macromolecule Biosynthetic Process Anatomical Structure Development Macromolecule Biosynthetic Process Limb Morphogenesis Positive Regulation Of Transcription From RNA Polymerase II Promoter Proximal/distal Pattern Formation Positive Regulation Of Transcription, DNA-templated Skeletal System Morphogenesis Nucleobase-containing Compound Metabolic Process Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Gene Expression Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Biosynthetic Process Positive Regulation Of Cellular Biosynthetic Process Embryonic Organ Morphogenesis Regulation Of Metabolic Process Embryonic Organ Development Cellular Nitrogen Compound Metabolic Process Chordate Embryonic Development Nitrogen Compound Metabolic Process Embryo Development Ending In Birth Or Egg Hatching Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Cellular Metabolic Process Embryonic Forelimb Morphogenesis
Tagcloud ?		11q23 asxl1 bcor blymphoid btg1 cdkn2a cgh ebf1 entity etv6 fulfilling ikzf1 immunophenotypic karyotyped lef1 mbnl1 mef2c monosomy myeloblastic notch1 p15 polysomy q11 q21 q34 runx1 stil tet2 trilineage	acetyltransferase aggressive characteristically emu fusing haploinsufficient hence homeobox hox includes kat6a localizes lymphoma maintain maintaining maintains malignancy menin mll1 moz myst3 ncoa3 overlap progenitor progenitors proliferative tale tif2 translocations
Tagcloud (Difference) ?		11q23 asxl1 bcor blymphoid btg1 cdkn2a cgh ebf1 entity etv6 fulfilling ikzf1 immunophenotypic karyotyped lef1 mbnl1 mef2c monosomy myeloblastic notch1 p15 polysomy q11 q21 q34 runx1 stil tet2 trilineage	acetyltransferase aggressive characteristically emu fusing haploinsufficient hence homeobox hox includes kat6a localizes lymphoma maintain maintaining maintains malignancy menin mll1 moz myst3 ncoa3 overlap progenitor progenitors proliferative tale tif2 translocations
Tagcloud (Intersection) ?