PBX3 and FAM177A1

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		PBX3	FAM177A1
Description		PBX homeobox 3	family with sequence similarity 177 member A1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Chromatin Nucleus Transcription Regulator Complex
	Molecular Function	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific DNA Binding DNA-binding Transcription Factor Activity Sequence-specific DNA Binding	Protein Binding
	Biological Process	Eye Development Regulation Of Respiratory Gaseous Exchange By Nervous System Process Regulation Of DNA-templated Transcription Anterior Compartment Pattern Formation Posterior Compartment Specification Brain Development Respiratory Gaseous Exchange By Respiratory System Adult Locomotory Behavior Animal Organ Morphogenesis Dorsal Spinal Cord Development Positive Regulation Of Transcription By RNA Polymerase II Embryonic Organ Development Neuron Development
Pathways
Drugs
Diseases
GWAS		Dentures ( 31235808) Fish- and plant-related diet ( 32066663) Medication use (opioids) ( 31015401) Number of decayed, missing and filled tooth surfaces or use of dentures ( 31235808) Pulse pressure ( 30578418) Raw vegetable consumption ( 32066663) Refractive error ( 32231278) Response to mTOR inhibitor (everolimus) ( 24009623) Sleep duration ( 30531941) Squamous cell lung carcinoma ( 28604730) Systolic blood pressure ( 30224653 30578418)	Bipolar disorder lithium response (continuous) or schizophrenia ( 29121268) Blood protein levels ( 30072576) Circulating fibroblast growth factor 23 levels ( 30217807) Colorectal carcinoma in primary sclerosing cholangitis ( 28779025) Hip index ( 34021172) Lymphocyte count ( 27863252 32888494) Monocyte percentage of white cells ( 27863252 32888494) Neutrophil percentage of white cells ( 32888494)
Interacting Genes		65 interacting genes: AGTRAP ARFIP2 ARL6IP1 BIK BSND CAV3 CFTR CIDEB CMTM4 CMTM5 COQ8A CPLX2 DESI2 DGAT2L6 FADS6 FAM177A1 FKBP7 FSD2 GAD2 GBP7 HIGD1C HOXA9 HOXB8 HSD17B13 INPP5K INSYN1 ITGB3BP KRT27 KRT31 LIME1 MAGEA1 MAGEC2 MAL2 MBLAC2 MDK MEIS1 MICOS13 MTERF3 NUDT9 PKNOX1 PLIN3 PRB3 PTPN9 RABAC1 REEP5 RHBDD2 RHEX RNF186 RPRM SCAMP1 SFT2D2 SIN3A SMPD2 SYP SYPL1 TFIP11 TMCO2 TMEM196 TPD52L1 TPM3 TRAF1 TRIM44 TVP23B ZNF655 ZNHIT3	9 interacting genes: AQP6 DPM3 ELOVL4 FATE1 JAGN1 PBX3 SGPL1 TMX2 TRAF6
Entrez ID		5090	283635
HPRD ID		15938	12644
Ensembl ID		ENSG00000167081	ENSG00000151327
Uniprot IDs		P40426 Q5JS98 Q96AL5	Q8N128
PDB IDs
Enriched GO Terms of Interacting Partners?		Protein Binding	Endoplasmic Reticulum Membrane Endoplasmic Reticulum Mitochondria-associated Endoplasmic Reticulum Membrane Contact Site Animal Organ Morphogenesis Membrane Lipid Metabolic Process Nitrate Transmembrane Transporter Activity Posterior Compartment Specification Anterior Compartment Pattern Formation Sphinganine-1-phosphate Aldolase Activity Endoplasmic Reticulum-plasma Membrane Adaptor Activity
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