PBX3 and GBP7

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		PBX3	GBP7
Description		PBX homeobox 3	guanylate binding protein 7
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Chromatin Nucleus Transcription Regulator Complex	Membrane Cytoplasmic Vesicle Membrane Cytoplasmic Vesicle
	Molecular Function	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific DNA Binding DNA-binding Transcription Factor Activity Sequence-specific DNA Binding	Nucleotide Binding GTPase Activity Protein Binding GTP Binding Hydrolase Activity
	Biological Process	Eye Development Regulation Of Respiratory Gaseous Exchange By Nervous System Process Regulation Of DNA-templated Transcription Anterior Compartment Pattern Formation Posterior Compartment Specification Brain Development Respiratory Gaseous Exchange By Respiratory System Adult Locomotory Behavior Animal Organ Morphogenesis Dorsal Spinal Cord Development Positive Regulation Of Transcription By RNA Polymerase II Embryonic Organ Development Neuron Development	Negative Regulation Of Cytokine Production Immune System Process Negative Regulation Of Type I Interferon Production Negative Regulation Of Type III Interferon Production Defense Response To Bacterium Defense Response To Protozoan Regulation Of Canonical NF-kappaB Signal Transduction Positive Regulation Of Viral Genome Replication Innate Immune Response Negative Regulation Of Receptor Signaling Pathway Via JAK-STAT Defense Response To Gram-positive Bacterium Defense Response To Virus Cytolysis In Another Organism Cellular Response To Type II Interferon
Pathways			Interferon gamma signaling
Drugs
Diseases
GWAS		Dentures ( 31235808) Fish- and plant-related diet ( 32066663) Medication use (opioids) ( 31015401) Number of decayed, missing and filled tooth surfaces or use of dentures ( 31235808) Pulse pressure ( 30578418) Raw vegetable consumption ( 32066663) Refractive error ( 32231278) Response to mTOR inhibitor (everolimus) ( 24009623) Sleep duration ( 30531941) Squamous cell lung carcinoma ( 28604730) Systolic blood pressure ( 30224653 30578418)
Interacting Genes		65 interacting genes: AGTRAP ARFIP2 ARL6IP1 BIK BSND CAV3 CFTR CIDEB CMTM4 CMTM5 COQ8A CPLX2 DESI2 DGAT2L6 FADS6 FAM177A1 FKBP7 FSD2 GAD2 GBP7 HIGD1C HOXA9 HOXB8 HSD17B13 INPP5K INSYN1 ITGB3BP KRT27 KRT31 LIME1 MAGEA1 MAGEC2 MAL2 MBLAC2 MDK MEIS1 MICOS13 MTERF3 NUDT9 PKNOX1 PLIN3 PRB3 PTPN9 RABAC1 REEP5 RHBDD2 RHEX RNF186 RPRM SCAMP1 SFT2D2 SIN3A SMPD2 SYP SYPL1 TFIP11 TMCO2 TMEM196 TPD52L1 TPM3 TRAF1 TRIM44 TVP23B ZNF655 ZNHIT3	2 interacting genes: CPNE2 PBX3
Entrez ID		5090	388646
HPRD ID		15938	13432
Ensembl ID		ENSG00000167081	ENSG00000213512
Uniprot IDs		P40426 Q5JS98 Q96AL5	Q8N8V2
PDB IDs
Enriched GO Terms of Interacting Partners?		Protein Binding	Posterior Compartment Specification Anterior Compartment Pattern Formation Dorsal Spinal Cord Development Compartment Pattern Specification Regulation Of Respiratory Gaseous Exchange By Nervous System Process Regulation Of Respiratory System Process Regulation Of Respiratory Gaseous Exchange Respiratory Gaseous Exchange By Respiratory System
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