MEIS1 and HOXD12

Number of citations of the paper that reports this interaction (PMID 9343407)
63

Data Source:
HPRD (in vitro)

		MEIS1	HOXD12
Gene Name		Meis homeobox 1	homeobox D12
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Transcription Factor Complex	Nucleus Transcription Factor Complex
	Molecular Function	RNA Polymerase II Core Promoter Proximal Region Sequence-specific DNA Binding RNA Polymerase II Core Promoter Proximal Region Sequence-specific DNA Binding Transcription Factor Activity Involved In Positive Regulation Of Transcription Chromatin Binding RNA Polymerase II Distal Enhancer Sequence-specific DNA Binding Transcription Factor Activity Protein Binding Protein Heterodimerization Activity	Sequence-specific DNA Binding
	Biological Process	Angiogenesis Lens Morphogenesis In Camera-type Eye Transcription From RNA Polymerase II Promoter Megakaryocyte Development Negative Regulation Of Myeloid Cell Differentiation Negative Regulation Of Neuron Differentiation Positive Regulation Of Transcription From RNA Polymerase II Promoter Definitive Hemopoiesis	Skeletal System Development Transcription, DNA-templated Regulation Of Transcription, DNA-templated Pattern Specification Process Embryonic Digit Morphogenesis
Pathways
Drugs
Diseases
GWAS		PR interval ( 20062060 23139255) Restless legs syndrome ( 17637780 21779176)
Protein-Protein Interactions		27 interactors: EMX2 ETS1 HOXA10 HOXA11 HOXA13 HOXA2 HOXA5 HOXA7 HOXA9 HOXB1 HOXB13 HOXB4 HOXB8 HOXC11 HOXC13 HOXD11 HOXD12 HOXD13 HOXD4 HOXD9 PBX1 PBX3 PKNOX1 TLX1 TLX2 TLX3 TRMT10B	8 interactors: CREBBP MAF MAFB MAFF MAFG MAFK MEIS1 TRAF1
Entrez ID		4211	3238
HPRD ID		03442	00871
Ensembl ID		ENSG00000143995	ENSG00000170178
Uniprot IDs		F5GYS8 F8W8U3 O00470	P35452
PDB IDs
Enriched GO Terms of Interacting Partners?		Anterior/posterior Pattern Specification Pattern Specification Process Embryonic Morphogenesis Transcription, DNA-templated Skeletal System Development Embryonic Skeletal System Development RNA Biosynthetic Process Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Anatomical Structure Morphogenesis Multicellular Organismal Development System Development Regulation Of Gene Expression Regulation Of Nitrogen Compound Metabolic Process Embryonic Skeletal System Morphogenesis RNA Metabolic Process Limb Development Embryo Development Gene Expression Organ Development Developmental Process Organ Morphogenesis Embryonic Limb Morphogenesis Cellular Macromolecule Biosynthetic Process Anatomical Structure Development Macromolecule Biosynthetic Process Limb Morphogenesis Positive Regulation Of Transcription From RNA Polymerase II Promoter Proximal/distal Pattern Formation Positive Regulation Of Transcription, DNA-templated Skeletal System Morphogenesis Nucleobase-containing Compound Metabolic Process Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Gene Expression Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Biosynthetic Process Positive Regulation Of Cellular Biosynthetic Process Embryonic Organ Morphogenesis Regulation Of Metabolic Process Embryonic Organ Development Cellular Nitrogen Compound Metabolic Process Chordate Embryonic Development Nitrogen Compound Metabolic Process Embryo Development Ending In Birth Or Egg Hatching Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Cellular Metabolic Process Embryonic Forelimb Morphogenesis	Transcription, DNA-templated RNA Biosynthetic Process Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Regulation Of Cell Differentiation Regulation Of Gene Expression Regulation Of Nitrogen Compound Metabolic Process RNA Metabolic Process Gene Expression Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Nucleobase-containing Compound Metabolic Process Regulation Of Epidermal Cell Differentiation Multicellular Organismal Development Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Biosynthetic Process Regulation Of Metabolic Process Anatomical Structure Development Transcription From RNA Polymerase II Promoter Cellular Nitrogen Compound Metabolic Process Regulation Of Epidermis Development Positive Regulation Of Transcription From RNA Polymerase II Promoter Developmental Process Nitrogen Compound Metabolic Process Blood Coagulation Hemostasis Embryo Development Rhombomere 6 Development Negative Regulation Of Myeloid Cell Differentiation Lens Development In Camera-type Eye Positive Regulation Of Transcription, DNA-templated Regulation Of Body Fluid Levels Sensory Organ Development Wound Healing Positive Regulation Of Macromolecule Biosynthetic Process Regulation Of Epithelial Cell Differentiation Brain Segmentation N-terminal Peptidyl-lysine Acetylation Positive Regulation Of Gene Expression Positive Regulation Of Cellular Biosynthetic Process Response To Wounding Rhombomere 5 Development Negative Regulation Of Cell Differentiation Regulation Of Myeloid Cell Differentiation Inner Ear Development Germ-line Stem Cell Maintenance Regulation Of Transcription From RNA Polymerase II Promoter
Tagcloud ?		acetyltransferase aggressive characteristically emu fusing haploinsufficient hence homeobox hox includes kat6a localizes lymphoma maintain maintaining maintains malignancy menin mll1 moz myst3 ncoa3 overlap progenitor progenitors proliferative tale tif2 translocations
Tagcloud (Difference) ?		acetyltransferase aggressive characteristically emu fusing haploinsufficient hence homeobox hox includes kat6a localizes lymphoma maintain maintaining maintains malignancy menin mll1 moz myst3 ncoa3 overlap progenitor progenitors proliferative tale tif2 translocations
Tagcloud (Intersection) ?