PBX3 and TRIM44

Number of citations of the paper that reports this interaction (PubMedID 25416956)
56

Data Source:
BioGRID (two hybrid)

		PBX3	TRIM44
Description		PBX homeobox 3	tripartite motif containing 44
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Chromatin Nucleus Transcription Regulator Complex	Cytoplasm
	Molecular Function	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific DNA Binding DNA-binding Transcription Factor Activity Sequence-specific DNA Binding	Protein Binding Zinc Ion Binding Metal Ion Binding Ubiquitin Protein Ligase Activity
	Biological Process	Eye Development Regulation Of Respiratory Gaseous Exchange By Nervous System Process Regulation Of DNA-templated Transcription Anterior Compartment Pattern Formation Posterior Compartment Specification Brain Development Respiratory Gaseous Exchange By Respiratory System Adult Locomotory Behavior Animal Organ Morphogenesis Dorsal Spinal Cord Development Positive Regulation Of Transcription By RNA Polymerase II Embryonic Organ Development Neuron Development	Positive Regulation Of Cytokine-mediated Signaling Pathway Positive Regulation Of Defense Response To Virus By Host Regulation Of Gene Expression Innate Immune Response Positive Regulation Of DNA-templated Transcription Protein Stabilization Negative Regulation Of Protein K48-linked Ubiquitination Positive Regulation Of Non-canonical NF-kappaB Signal Transduction
Pathways
Drugs
Diseases
GWAS		Dentures ( 31235808) Fish- and plant-related diet ( 32066663) Medication use (opioids) ( 31015401) Number of decayed, missing and filled tooth surfaces or use of dentures ( 31235808) Pulse pressure ( 30578418) Raw vegetable consumption ( 32066663) Refractive error ( 32231278) Response to mTOR inhibitor (everolimus) ( 24009623) Sleep duration ( 30531941) Squamous cell lung carcinoma ( 28604730) Systolic blood pressure ( 30224653 30578418)	Metabolite levels ( 23823483) Photic sneeze reflex ( 27182965) Response to antipsychotic therapy (extrapyramidal side effects) ( 19875103)
Interacting Genes		65 interacting genes: AGTRAP ARFIP2 ARL6IP1 BIK BSND CAV3 CFTR CIDEB CMTM4 CMTM5 COQ8A CPLX2 DESI2 DGAT2L6 FADS6 FAM177A1 FKBP7 FSD2 GAD2 GBP7 HIGD1C HOXA9 HOXB8 HSD17B13 INPP5K INSYN1 ITGB3BP KRT27 KRT31 LIME1 MAGEA1 MAGEC2 MAL2 MBLAC2 MDK MEIS1 MICOS13 MTERF3 NUDT9 PKNOX1 PLIN3 PRB3 PTPN9 RABAC1 REEP5 RHBDD2 RHEX RNF186 RPRM SCAMP1 SFT2D2 SIN3A SMPD2 SYP SYPL1 TFIP11 TMCO2 TMEM196 TPD52L1 TPM3 TRAF1 TRIM44 TVP23B ZNF655 ZNHIT3	10 interacting genes: APP FBXO7 HINFP MORN4 NEDD4 PBX3 PICK1 TRIM10 TRIM69 UBC
Entrez ID		5090	54765
HPRD ID		15938	15561
Ensembl ID		ENSG00000167081	ENSG00000166326
Uniprot IDs		P40426 Q5JS98 Q96AL5	Q96DX7
PDB IDs
Enriched GO Terms of Interacting Partners?		Protein Binding	Amyloid-beta Complex Innate Immune Response Growth Cone Lamellipodium Neuron Projection Organization Defense Response To Symbiont Regulation Of Response To Calcium Ion Response To Stress Amylin Binding Positive Regulation Of Toll Signaling Pathway Positive Regulation Of Receptor-mediated Endocytosis Positive Regulation Of Receptor Internalization Glial Cell Development Protein Modification By Small Protein Conjugation Ubiquitin-protein Transferase Activity Protein Ubiquitination Formation Of Structure Involved In A Symbiotic Process Posterior Compartment Specification Anterior Compartment Pattern Formation Glial Cytoplasmic Inclusion Classical Lewy Body Lewy Body Corona Lewy Neurite Defense Response To Other Organism G Protein-coupled Receptor Binding Regulation Of Receptor Internalization Endocytic Vesicle Membrane Adult Locomotory Behavior Post-translational Protein Modification Ubiquitin Protein Ligase Activity Acetylcholine Receptor Activator Activity Lipoprotein Particle Positive Regulation Of Protein Import Channel Inhibitor Activity PTB Domain Binding Collateral Sprouting In Absence Of Injury Regulation Of Protein Import Enzyme Binding Trans-Golgi Network Membrane Endosome To Plasma Membrane Transport Vesicle Positive Regulation Of Endothelin Production Growth Cone Filopodium Phospholipase D-activating G Protein-coupled Receptor Signaling Pathway Microglia Development Positive Regulation Of G Protein-coupled Receptor Internalization Protein Modification Process Ubiquitin Ligase Complex Phosphothreonine Residue Binding Ubiquitin Binding Lewy Body Core Response To Norepinephrine
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