YLPM1 and PRMT2

Number of citations of the paper that reports this interaction (PubMedID 35914814)
83

Data Source:
BioGRID (two hybrid)

		YLPM1	PRMT2
Description		YLP motif containing 1	protein arginine methyltransferase 2
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Nuclear Speck	Nucleus Nucleoplasm Nucleolus Cytoplasm Cytosol
	Molecular Function	RNA Binding Protein Binding	Transcription Coactivator Activity Protein Binding Methyltransferase Activity Protein-arginine N-methyltransferase Activity Transferase Activity Nuclear Estrogen Receptor Binding Nuclear Progesterone Receptor Binding Protein-arginine Omega-N Asymmetric Methyltransferase Activity Histone Methyltransferase Activity Protein Homodimerization Activity Nuclear Retinoic Acid Receptor Binding Peroxisome Proliferator Activated Receptor Binding Protein-containing Complex Binding Nuclear Thyroid Hormone Receptor Binding Nuclear Androgen Receptor Binding Histone H3R8 Methyltransferase Activity Histone H3 Methyltransferase Activity
	Biological Process	Regulation Of Telomere Maintenance	Chromatin Remodeling Regulation Of DNA-templated Transcription Protein Methylation Signal Transduction Negative Regulation Of NF-kappaB Transcription Factor Activity Methylation Positive Regulation Of Apoptotic Process Negative Regulation Of Canonical NF-kappaB Signal Transduction Negative Regulation Of DNA-templated Transcription Positive Regulation Of DNA-templated Transcription Developmental Cell Growth Negative Regulation Of Inflammatory Response Regulation Of Androgen Receptor Signaling Pathway Negative Regulation Of G1/S Transition Of Mitotic Cell Cycle
Pathways
Drugs
Diseases
GWAS		Apolipoprotein A1 levels ( 32203549) Gastroesophageal reflux disease ( 34187846) General factor of neuroticism ( 30867560) Macular thickness ( 30535121) Mood instability ( 29187730) Platelet count ( 27863252 32888494) Plateletcrit ( 32888494)	Diverticular disease ( 30177863)
Interacting Genes		12 interacting genes: APBB1 BMP1 CACNA1A CHGB GRB2 ITSN2 PPP1CA PPP1CC PRMT1 PRMT2 PRPF40A TSG101	37 interacting genes: BAG6 CBLB CHEK2 CPSF7 DAZAP1 DMRTB1 ESR1 ESR2 FIP1L1 HNRNPA1 HNRNPUL1 IQSEC2 KDM6B MYO6 NCOA1 NCOA6 PGR PRMT8 PRRC2A PSMB3 R3HDM1 RB1 RBM12 RBM22 RIPK2 RXRA SHANK1 SHANK3 SHTN1 SPAG8 THRB WASL WBP11 YLPM1 ZFP36 ZNF341 ZSWIM8
Entrez ID		56252	3275
HPRD ID		11688	09060
Ensembl ID		ENSG00000119596	ENSG00000160310
Uniprot IDs		F8VU51 P49750	A0A0S2Z3N3 P55345
PDB IDs			1X2P
Enriched GO Terms of Interacting Partners?		Protein-arginine Omega-N Asymmetric Methyltransferase Activity PTW/PP1 Phosphatase Complex Protein-arginine N-methyltransferase Activity Protein-containing Complex Binding Protein Phosphatase 1 Binding Photoperiodism Entrainment Of Circadian Clock By Photoperiod Entrainment Of Circadian Clock Cell Division Histone Methyltransferase Activity Protein Methylation Guanyl-nucleotide Exchange Factor Adaptor Activity Histone H3R8 Methyltransferase Activity GATOR1 Complex Binding Glycogen Metabolic Process Negative Regulation Of Cell Cycle G1/S Phase Transition Grb2-EGFR Complex Nuclear Progesterone Receptor Binding Circadian Regulation Of Gene Expression Energy Reserve Metabolic Process Phosphatase Activity RNA Polymerase II CTD Heptapeptide Repeat S5 Phosphatase Activity Polysaccharide Metabolic Process Positive Regulation Of Ubiquitin-dependent Endocytosis Clathrin-dependent Synaptic Vesicle Endocytosis Amyloid-beta Binding DNA Damage Response Protein Dephosphorylation Protein Serine/threonine Phosphatase Activity Protein Phosphatase Binding Protein Localization To Vacuole Positive Regulation Of Termination Of RNA Polymerase II Transcription, Poly(A)-coupled Positive Regulation Of Viral Budding Via Host ESCRT Complex	Positive Regulation Of RNA Metabolic Process Positive Regulation Of Nucleobase-containing Compound Metabolic Process Enzyme Binding Nucleoplasm Positive Regulation Of Macromolecule Metabolic Process Positive Regulation Of Macromolecule Biosynthetic Process Nuclear Receptor-mediated Signaling Pathway Nuclear Receptor Activity Positive Regulation Of Biosynthetic Process Nuclear Steroid Receptor Activity Nucleus Regulation Of Thyroid Hormone Receptor Signaling Pathway Positive Regulation Of Metabolic Process Regulation Of Primary Metabolic Process MRNA Metabolic Process Intracellular Receptor Signaling Pathway RNA Metabolic Process Steroid Hormone Receptor Signaling Pathway Nuclear Receptor-mediated Steroid Hormone Signaling Pathway Hormone-mediated Signaling Pathway Positive Regulation Of DNA-templated Transcription Positive Regulation Of RNA Biosynthetic Process Regulation Of Nucleobase-containing Compound Metabolic Process Positive Regulation Of Transcription By RNA Polymerase II Regulation Of RNA Metabolic Process Estrogen Response Element Binding Intracellular Signal Transduction Regulation Of Macromolecule Metabolic Process Sequence-specific DNA Binding Dendritic Spine Morphogenesis Nucleic Acid Metabolic Process Positive Regulation Of Thyroid Hormone Receptor Signaling Pathway Estrogen Receptor Signaling Pathway Regulation Of Gene Expression Regulation Of Metabolic Process Regulation Of Macromolecule Biosynthetic Process Nuclear Estrogen Receptor Activity Synaptic Receptor Adaptor Activity Regulation Of Transcription By RNA Polymerase II Steroid Binding Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process Dendritic Spine Organization RNA Binding Nuclear Estrogen Receptor Binding Neuron Projection Organization Postsynapse Organization Regulation Of Female Receptivity Female Mating Behavior MRNA Transcription By RNA Polymerase II
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