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RGS20 and GNAI1
Number of citations of the paper that reports this interaction (PMID
12379657
)
7
Data Source:
HPRD
(in vivo, in vitro, two hybrid)
RGS20
GNAI1
Gene Name
regulator of G-protein signaling 20
guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1
Image
No pdb structure
Gene Ontology Annotations
Cellular Component
Nucleus
Cytoplasm
Plasma Membrane
Nucleus
Cytoplasm
Lysosomal Membrane
Centrosome
Heterotrimeric G-protein Complex
Plasma Membrane
Midbody
Extracellular Vesicular Exosome
Molecular Function
GTPase Activator Activity
Protein Binding
GTPase Activity
Signal Transducer Activity
Protein Binding
GTP Binding
G-protein Beta/gamma-subunit Complex Binding
G-protein Coupled Serotonin Receptor Binding
Metal Ion Binding
Biological Process
Regulation Of G-protein Coupled Receptor Protein Signaling Pathway
Termination Of G-protein Coupled Receptor Signaling Pathway
Positive Regulation Of GTPase Activity
Cell Cycle
G-protein Coupled Receptor Signaling Pathway
Adenylate Cyclase-modulating G-protein Coupled Receptor Signaling Pathway
Adenylate Cyclase-inhibiting G-protein Coupled Receptor Signaling Pathway
Synaptic Transmission
Blood Coagulation
Platelet Activation
Response To Peptide Hormone
Cell Division
Pathways
Signaling by GPCR
GPCR downstream signaling
G alpha (z) signalling events
G alpha (i) signalling events
Signaling by GPCR
Integration of energy metabolism
G alpha (s) signalling events
Activation of GABAB receptors
Signal amplification
G alpha (z) signalling events
G alpha (i) signalling events
Neurotransmitter Receptor Binding And Downstream Transmission In The Postsynaptic Cell
ADP signalling through P2Y purinoceptor 12
GABA B receptor activation
Adenylate cyclase inhibitory pathway
GABA receptor activation
PLC beta mediated events
Opioid Signalling
Regulation of insulin secretion
G-protein mediated events
Adrenaline,noradrenaline inhibits insulin secretion
Inhibition of adenylate cyclase pathway
Adenylate cyclase inhibitory pathway
GPCR downstream signaling
G-protein activation
Platelet activation, signaling and aggregation
Transmission across Chemical Synapses
Drugs
Diseases
GWAS
Protein-Protein Interactions
33 interactors:
ADRB2
AQP1
CATSPER1
CRCT1
CREB5
FASLG
GLRX3
GNAI1
GNAI2
GNAI3
GNAO1
GNAZ
HOXA1
HSPD1
INS
KIF1A
KLHL38
KRTAP4-2
KRTAP5-6
KRTAP5-9
LCE1B
LCE2A
LCE2D
LCE3E
LCE4A
MAPKBP1
OSTM1
OTX1
PTGER3
PTPMT1
PVRL3
STMN2
TBC1D16
57 interactors:
ADCY5
ADRA2A
CCR5
CD47
CNR1
CRHR1
CXCR4
DRD3
EPOR
ESR1
FFAR1
GNAO1
GNB2
GNB4
GPR1
GPR143
GPSM1
GPSM2
GPSM3
HRH4
HTR2A
IGF1R
KLHL3
MTNR1A
MTNR1B
NGB
NUCB1
NUMA1
OPRD1
OPRM1
PDE6D
PTPRU
RANGAP1
RASD1
RGS10
RGS12
RGS14
RGS16
RGS17
RGS18
RGS19
RGS20
RGS4
RGS7
RIC8A
S1PR1
S1PR2
S1PR3
S1PR4
S1PR5
SSTR2
SSTR3
STRN
THAP7
TSHR
VIPR1
WASF1
Entrez ID
8601
2770
HPRD ID
06225
00756
Ensembl ID
ENSG00000147509
ENSG00000127955
Uniprot IDs
H9NIM5
O76081
P63096
PDB IDs
1KJY
1Y3A
2G83
2GTP
2IK8
2OM2
2PZ3
2XNS
3ONW
3QE0
3QI2
3UMR
3UMS
4G5Q
Enriched GO Terms of Interacting Partners
?
Adenylate Cyclase-modulating G-protein Coupled Receptor Signaling Pathway
G-protein Coupled Receptor Signaling Pathway, Coupled To Cyclic Nucleotide Second Messenger
Keratinization
Keratinocyte Differentiation
Epidermis Development
Developmental Process
Epidermal Cell Differentiation
Adenylate Cyclase-inhibiting G-protein Coupled Receptor Signaling Pathway
Organ Development
System Development
Multicellular Organismal Development
Anatomical Structure Development
Skin Development
Heat Generation
G-protein Coupled Receptor Signaling Pathway
Cell Differentiation
Regulation Of Adenylate Cyclase Activity
Regulation Of Cyclase Activity
Tissue Development
Regulation Of CAMP Biosynthetic Process
Epithelium Development
Regulation Of CAMP Metabolic Process
Negative Regulation Of Adenylate Cyclase Activity
Negative Regulation Of Lyase Activity
Epithelial Cell Differentiation
Temperature Homeostasis
Membrane Fusion
Regulation Of Body Fluid Levels
Cell-cell Signaling
Negative Regulation Of CAMP Biosynthetic Process
Sensory Organ Development
Wound Healing
Bicarbonate Transport
Negative Regulation Of CAMP Metabolic Process
Eye Morphogenesis
Cell Activation
Negative Regulation Of Nucleotide Metabolic Process
Acute-phase Response
Regulation Of Catalytic Activity
Response To Wounding
Metanephric Descending Thin Limb Development
Metanephric Proximal Straight Tubule Development
Metanephric Proximal Convoluted Tubule Segment 2 Development
Abducens Nerve Formation
B Cell Cytokine Production
Maintenance Of Symbiont-containing Vacuole By Host
Transepithelial Water Transport
Optokinetic Behavior
Isotype Switching To IgG Isotypes
Anion Homeostasis
G-protein Coupled Receptor Signaling Pathway
G-protein Coupled Receptor Signaling Pathway, Coupled To Cyclic Nucleotide Second Messenger
Cell Surface Receptor Signaling Pathway
Adenylate Cyclase-modulating G-protein Coupled Receptor Signaling Pathway
Regulation Of G-protein Coupled Receptor Protein Signaling Pathway
Signal Transduction
Negative Regulation Of G-protein Coupled Receptor Protein Signaling Pathway
Signaling
Cell Communication
Regulation Of Catalytic Activity
Termination Of G-protein Coupled Receptor Signaling Pathway
Termination Of Signal Transduction
Cellular Response To Stimulus
Adenylate Cyclase-inhibiting G-protein Coupled Receptor Signaling Pathway
Positive Regulation Of Catalytic Activity
Response To Stimulus
Regulation Of Signaling
Positive Regulation Of Hydrolase Activity
Positive Regulation Of Cytosolic Calcium Ion Concentration
Sphingosine-1-phosphate Signaling Pathway
Regulation Of Cellular Process
Chemical Homeostasis
Cell-cell Signaling
Cytosolic Calcium Ion Homeostasis
Positive Regulation Of GTPase Activity
Cellular Calcium Ion Homeostasis
Calcium Ion Homeostasis
Phospholipase C-activating G-protein Coupled Receptor Signaling Pathway
Regulation Of GTPase Activity
Positive Regulation Of Metabolic Process
Regulation Of Signal Transduction
Synaptic Transmission
Negative Regulation Of Signaling
Behavior
Cellular Metal Ion Homeostasis
Neuropeptide Signaling Pathway
Adenylate Cyclase-activating G-protein Coupled Receptor Signaling Pathway
Cellular Cation Homeostasis
Ion Homeostasis
Cellular Ion Homeostasis
Homeostatic Process
Metal Ion Homeostasis
Negative Regulation Of Signal Transduction
Cellular Chemical Homeostasis
Locomotory Behavior
Response To Ammonium Ion
Negative Regulation Of Ion Transport
Response To Cocaine
Regulation Of Cell Proliferation
Neurological System Process
Tagcloud
?
alkenes
azotic
constructions
gnao1
heterocycle
hm
hms
htr1b
htr2a
htr2b
htr4
htr6
htr7
kpnb1
pharmacopeia
prkaca
prkca
prkcb
prkcd
prkce
prkcg
prkd1
propertied
pubchem
rock2
rps6ka1
rps6ka3
tlr8
tradition
Tagcloud (Difference)
?
alkenes
azotic
constructions
gnao1
heterocycle
hm
hms
htr1b
htr2a
htr2b
htr4
htr6
htr7
kpnb1
pharmacopeia
prkaca
prkca
prkcb
prkcd
prkce
prkcg
prkd1
propertied
pubchem
rock2
rps6ka1
rps6ka3
tlr8
tradition
Tagcloud (Intersection)
?