RGS20 and RANBP3

Number of citations: 50 (PubMedID 32296183)
Data Source: BioGRID (two hybrid)

		RGS20	RANBP3
Name		regulator of G protein signaling 20	RAN binding protein 3
Structure		No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm Trans-Golgi Network Plasma Membrane Membrane	Nucleus Nucleoplasm Cytoplasm
	Molecular Function	GTPase Activity GTPase Activator Activity Protein Binding	Protein Binding Small GTPase Binding R-SMAD Binding
	Biological Process	G Protein-coupled Receptor Signaling Pathway Regulation Of G Protein-coupled Receptor Signaling Pathway Negative Regulation Of Signal Transduction	Protein Export From Nucleus Protein Transport
Pathways		G alpha (i) signalling events G alpha (i) signalling events G alpha (z) signalling events G alpha (z) signalling events	None
GWAS		Cerebrospinal fluid beta-site APP cleaving enzyme levels ( 29751835 ) Chronic obstructive pulmonary disease ( 32222710 ) Serum uric acid levels ( 29559957 ) Urinary albumin-to-creatinine ratio ( 26631737 )	Monocyte percentage of white cells ( 32888494 )
Interacting Genes		58 interacting genes: ABHD17A ADRB2 ALPP AQP1 CATSPER1 COL8A1 CRCT1 CREB5 FASLG GLRX3 GNAI1 GNAI2 GNAI3 GNAO1 GNAZ HOXA1 HRG HSPD1 INS KIF1A KLHL38 KRTAP4-2 KRTAP5-11 KRTAP5-3 KRTAP5-4 KRTAP5-6 KRTAP5-9 KRTAP9-3 KRTAP9-8 LCE1A LCE1B LCE1D LCE1E LCE1F LCE2A LCE2B LCE2C LCE2D LCE3A LCE3C LCE3D LCE3E LCE4A LCE5A LNX1 MAPKBP1 NECTIN2 NECTIN3 NEK8 NUFIP2 OSTM1 OTX1 PTGER3 PTPMT1 RANBP3 STMN2 TBC1D16 VASN	24 interacting genes: ANKS1A BLZF1 CHN2 GMCL1 GOLGA2 HOXA1 KLHL20 KPNA4 KPNB1 KPRP KRTAP1-3 KRTAP10-8 KRTAP13-1 KRTAP7-1 MEOX1 PAX6 PBX4 RAN RCC1 RGS20 TEPSIN TRAF2 XPO1 ZMIZ2
Entrez ID		8601	8498
HPRD ID		06225	04508
Ensembl ID		ENSG00000147509	ENSG00000031823
Uniprot IDs		B3KSW4 H9NIM5 O76081	B7Z7F3 Q53GE1 Q9H6Z4
PDB IDs		Not available	2CRF 2Y8F 2Y8G 5XZX
GO Terms Enriched among Interactors		Keratinization Epidermis Development Tissue Development Guanyl Nucleotide Binding G-protein Beta/gamma-subunit Complex Binding G Protein-coupled Serotonin Receptor Binding Intermediate Filament Heterotrimeric G-protein Complex Identical Protein Binding Protein Binding Adenylate Cyclase-inhibiting G Protein-coupled Receptor Signaling Pathway Adenylate Cyclase-modulating G Protein-coupled Receptor Signaling Pathway Negative Regulation Of Secretion Positive Regulation Of Immune Response To Tumor Cell G Protein-coupled Serotonin Receptor Signaling Pathway Neuronal Dense Core Vesicle Adenylate Cyclase Inhibitor Activity Adenylate Cyclase Regulator Activity G Protein-coupled Receptor Binding Negative Regulation Of Protein Secretion Regulation Of Response To Tumor Cell Negative Regulation Of Secretion By Cell Negative Regulation Of Insulin Secretion Adenylate Cyclase-inhibiting Serotonin Receptor Signaling Pathway Negative Regulation Of Peptide Secretion Hippocampal Mossy Fiber To CA3 Synapse Negative Regulation Of Adenylate Cyclase Activity Negative Regulation Of Protein Transport Negative Regulation Of Protein Localization Developmental Process Adhesion Of Symbiont To Host	Importin-alpha Family Protein Binding Microtubule Cytoskeleton Organization Involved In Mitosis Mitotic Spindle Organization RNA Import Into Nucleus Ribosomal Large Subunit Export From Nucleus Ribosomal Small Subunit Export From Nucleus Spindle Organization Protein Localization To Nucleus NLS-dependent Protein Nuclear Import Complex HMG Box Domain Binding Nuclear Export Signal Receptor Activity Ribosomal Subunit Export From Nucleus Intermediate Filament Nuclear Pore Microtubule Cytoskeleton Organization Spindle Assembly Positive Regulation Of Hippo Signaling Nuclear Import Signal Receptor Activity Keratin Filament Nuclear Transport Nucleocytoplasmic Transport Nuclear Localization Sequence Binding Chromatin Protein Transport NLS-bearing Protein Import Into Nucleus Establishment Of Organelle Localization Protein Import Into Nucleus Import Into Nucleus Protein Export From Nucleus Establishment Of Protein Localization Semicircular Canal Formation RNA Transport Forebrain-midbrain Boundary Formation Signal Transduction Involved In Regulation Of Gene Expression Pancreatic A Cell Development TORC2 Complex Disassembly Type II Interferon Binding Coated Vesicle Membrane Establishment Of Mitotic Spindle Localization Protein Localization To Organelle Mitotic Spindle Assembly Regulation Of Hippo Signaling Cytoskeleton Organization Intracellular Protein Localization Cis-Golgi Network Abducens Nerve Formation Optokinetic Behavior Establishment Of Spindle Localization Male Germ Cell Nucleus RNA Nuclear Export Complex