NME3 and SGTA

Number of citations of the paper that reports this interaction (PMID 16189514)
699

Data Source:
BioGRID (two hybrid, two hybrid)
HPRD (two hybrid)

		NME3	SGTA
Gene Name		NME/NM23 nucleoside diphosphate kinase 3	small glutamine-rich tetratricopeptide repeat (TPR)-containing, alpha
Image
Gene Ontology Annotations	Cellular Component	Mitochondrion Cytosol Extracellular Vesicular Exosome	Cytoplasm
	Molecular Function	Nucleoside Diphosphate Kinase Activity ATP Binding Metal Ion Binding	Protein Binding
	Biological Process	Purine Nucleotide Metabolic Process Nucleoside Diphosphate Phosphorylation GTP Biosynthetic Process Pyrimidine Nucleotide Metabolic Process UTP Biosynthetic Process CTP Biosynthetic Process Apoptotic Process Nucleoside Triphosphate Biosynthetic Process Regulation Of Apoptotic Process	Biological_process Viral Process
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions		8 interactors: APP HTR2A JAM2 NME1 NME2 SGTA UBQLN1 UBQLN4	92 interactors: ADIPOQ AGR3 BAG6 BCL2L12 C1QA C1QTNF1 C1QTNF6 C3orf52 CARKD CCDC155 CD79B CD99 CDH15 COL1A2 COL8A2 CSF1 CST1 CTSL CXCL8 EFEMP1 EFEMP2 ERP27 EVA1B F11R FERD3L FIP1L1 FKBP7 FXYD7 GABARAPL2 GAL GHR GIP GPX7 GRN GYPA HSP90AA1 HSP90AB1 HSPA13 HSPA8 IGL IGLC1 IRF3 IRF5 ITPRIPL1 KRT6A KTN1 LAIR2 LAT MSMB MSTN MYDGF NME3 NXF1 PBXIP1 PCDHA4 PFN2 PIAS1 PPIB PPIC PPP1R3C PRAP1 PTN RARRES3 RPN1 SDC4 SERPINE1 SGCA SLPI SMAGP SOD3 SPP1 SPPL2A SRGN SYT11 SYT4 TFF3 TFRC TGFA TMEM174 TMEM31 TMPO TMUB2 TNFRSF13B TNFRSF1A TWSG1 TXNDC12 UBL4A UPK3A VIP WBP1L ZG16 ZG16B
Entrez ID		4832	6449
HPRD ID		03488	04568
Ensembl ID		ENSG00000103024	ENSG00000104969
Uniprot IDs		Q13232	O43765
PDB IDs		1ZS6	2VYI 4GOD 4GOE 4GOF
Enriched GO Terms of Interacting Partners?		Nucleobase-containing Small Molecule Interconversion GTP Biosynthetic Process UTP Biosynthetic Process GTP Metabolic Process UTP Metabolic Process CTP Biosynthetic Process Nucleoside Diphosphate Phosphorylation Pyrimidine Ribonucleotide Biosynthetic Process Pyrimidine Nucleoside Biosynthetic Process Pyrimidine Nucleotide Biosynthetic Process Nucleotide Phosphorylation Nucleoside Diphosphate Metabolic Process Pyrimidine Nucleoside Metabolic Process Pyrimidine Nucleotide Metabolic Process Nucleoside Triphosphate Biosynthetic Process Cellular Chemical Homeostasis Phospholipase C-activating Serotonin Receptor Signaling Pathway Synaptic Growth At Neuromuscular Junction Collateral Sprouting In Absence Of Injury Positive Regulation Of Epithelial Cell Proliferation Cellular Homeostasis Positive Regulation Of Phosphatidylinositol Biosynthetic Process Purine Nucleotide Biosynthetic Process Adult Behavior Ribose Phosphate Biosynthetic Process Collateral Sprouting Axon Midline Choice Point Recognition Smooth Endoplasmic Reticulum Calcium Ion Homeostasis Positive Regulation Of Phospholipid Biosynthetic Process Positive Regulation Of Cell Proliferation Regulation Of Peptidyl-tyrosine Phosphorylation Axon Choice Point Recognition Chemical Homeostasis Regulation Of Cellular Protein Metabolic Process Artery Smooth Muscle Contraction Purine Nucleoside Metabolic Process Tonic Smooth Muscle Contraction Neuron Remodeling Regulation Of Binding Learning Or Memory Urinary Bladder Smooth Muscle Contraction Peptidyl-histidine Phosphorylation Regulation Of Protein Metabolic Process Regulation Of Epithelial Cell Proliferation Cognition Ribonucleotide Metabolic Process Nucleoside Metabolic Process Cellular Calcium Ion Homeostasis Nucleotide Biosynthetic Process Positive Regulation Of Glycolytic Process	Response To Stress Protein Heterotrimerization Extracellular Matrix Organization Extracellular Structure Organization Defense Response Regulation Of Immune System Process Protein Trimerization Macrophage Apoptotic Process Response To Wounding Regulation Of Secretion Immune System Process Regulation Of Protein Metabolic Process Anatomical Structure Development Regulation Of Cell Proliferation Protein Heterooligomerization Cell Communication Cell Surface Receptor Signaling Pathway Response To Stimulus Positive Regulation Of Phosphorylation Positive Regulation Of Protein Phosphorylation Regulation Of Cellular Localization Positive Regulation Of Immune System Process Wound Healing Regulation Of Cellular Protein Metabolic Process Signaling Regulation Of Cellular Response To Heat Negative Regulation Of Proteolysis Positive Regulation Of Protein Modification Process Negative Regulation Of Protein Processing Developmental Process Multicellular Organismal Metabolic Process Tail-anchored Membrane Protein Insertion Into ER Membrane Innate Immune Response Cellular Response To Stimulus Regulation Of Cytokine-mediated Signaling Pathway Extracellular Matrix Disassembly Myeloid Cell Apoptotic Process Response To Organic Substance Protein Folding Regulation Of Protein Processing Response To Lipid Regulation Of Developmental Growth Protein Insertion Into ER Membrane Inflammatory Cell Apoptotic Process Positive Regulation Of Cellular Metabolic Process System Development Regulation Of Immune Response Inflammatory Response Signal Transduction Positive Regulation Of Protein Metabolic Process
Tagcloud ?		address affecting arhgdib autonomous bcl3 concomitant deregulated dissociation erbb2 gdp intrinsic lungs malignancy mammary metalloprotease mmtv modifying motility neu nme1 nme2 oncogene oncogenic proto rescued solid timp1 timp2 turnover	bag6 biochemically biophysical calorimetry compete connecting decided dimerisation glutamine haddock helices hydrophobic isothermal itc microscale mst nt paths perturbation resides solve tetratricopeptide thermophoresis titration tpr trc35 trimeric ubl ubl4a
Tagcloud (Difference) ?		address affecting arhgdib autonomous bcl3 concomitant deregulated dissociation erbb2 gdp intrinsic lungs malignancy mammary metalloprotease mmtv modifying motility neu nme1 nme2 oncogene oncogenic proto rescued solid timp1 timp2 turnover	bag6 biochemically biophysical calorimetry compete connecting decided dimerisation glutamine haddock helices hydrophobic isothermal itc microscale mst nt paths perturbation resides solve tetratricopeptide thermophoresis titration tpr trc35 trimeric ubl ubl4a
Tagcloud (Intersection) ?