NME3 and NME1

Number of citations of the paper that reports this interaction (PMID 11042679)
5

Data Source:
HPRD (in vivo)

		NME3	NME1
Gene Name		NME/NM23 nucleoside diphosphate kinase 3	NME/NM23 nucleoside diphosphate kinase 1
Image
Gene Ontology Annotations	Cellular Component	Mitochondrion Cytosol Extracellular Vesicular Exosome	Nucleus Cytoplasm Mitochondrion Cytosol Membrane Ruffle Membrane Extracellular Vesicular Exosome
	Molecular Function	Nucleoside Diphosphate Kinase Activity ATP Binding Metal Ion Binding	Magnesium Ion Binding Deoxyribonuclease Activity Nucleoside Diphosphate Kinase Activity Protein Binding ATP Binding GTP Binding Identical Protein Binding Ribosomal Small Subunit Binding Poly(A) RNA Binding
	Biological Process	Purine Nucleotide Metabolic Process Nucleoside Diphosphate Phosphorylation GTP Biosynthetic Process Pyrimidine Nucleotide Metabolic Process UTP Biosynthetic Process CTP Biosynthetic Process Apoptotic Process Nucleoside Triphosphate Biosynthetic Process Regulation Of Apoptotic Process	Purine Nucleotide Metabolic Process Nucleoside Diphosphate Phosphorylation GTP Biosynthetic Process Pyrimidine Nucleotide Metabolic Process UTP Biosynthetic Process CTP Biosynthetic Process DNA Catabolic Process Endocytosis Nervous System Development Negative Regulation Of Cell Proliferation Nucleoside Triphosphate Biosynthetic Process Nucleobase-containing Small Molecule Interconversion Cell Differentiation Regulation Of Apoptotic Process Positive Regulation Of DNA Binding Small Molecule Metabolic Process Positive Regulation Of Epithelial Cell Proliferation Nucleobase-containing Small Molecule Metabolic Process
Pathways			Metabolism of nucleotides Synthesis and interconversion of nucleotide di- and triphosphates
Drugs
Diseases
GWAS
Protein-Protein Interactions		8 interactors: APP HTR2A JAM2 NME1 NME2 SGTA UBQLN1 UBQLN4	27 interactors: APEX1 AURKA CCND3 FXR2 GORASP2 ITGB1 KSR1 MIF NIF3L1 NME2 NME3 NME4 PID1 POLR1C PRUNE RAC1 RORA RORB RRAD SET SMARCD1 SOX30 SREK1IP1 TERF1 TIAM1 TNPO2 WDYHV1
Entrez ID		4832	4830
HPRD ID		03488	01131
Ensembl ID		ENSG00000103024	ENSG00000239672
Uniprot IDs		Q13232	P15531
PDB IDs		1ZS6	1JXV 1UCN 2HVD 2HVE 3L7U 4ENO
Enriched GO Terms of Interacting Partners?		Nucleobase-containing Small Molecule Interconversion GTP Biosynthetic Process UTP Biosynthetic Process GTP Metabolic Process UTP Metabolic Process CTP Biosynthetic Process Nucleoside Diphosphate Phosphorylation Pyrimidine Ribonucleotide Biosynthetic Process Pyrimidine Nucleoside Biosynthetic Process Pyrimidine Nucleotide Biosynthetic Process Nucleotide Phosphorylation Nucleoside Diphosphate Metabolic Process Pyrimidine Nucleoside Metabolic Process Pyrimidine Nucleotide Metabolic Process Nucleoside Triphosphate Biosynthetic Process Cellular Chemical Homeostasis Phospholipase C-activating Serotonin Receptor Signaling Pathway Synaptic Growth At Neuromuscular Junction Collateral Sprouting In Absence Of Injury Positive Regulation Of Epithelial Cell Proliferation Cellular Homeostasis Positive Regulation Of Phosphatidylinositol Biosynthetic Process Purine Nucleotide Biosynthetic Process Adult Behavior Ribose Phosphate Biosynthetic Process Collateral Sprouting Axon Midline Choice Point Recognition Smooth Endoplasmic Reticulum Calcium Ion Homeostasis Positive Regulation Of Phospholipid Biosynthetic Process Positive Regulation Of Cell Proliferation Regulation Of Peptidyl-tyrosine Phosphorylation Axon Choice Point Recognition Chemical Homeostasis Regulation Of Cellular Protein Metabolic Process Artery Smooth Muscle Contraction Purine Nucleoside Metabolic Process Tonic Smooth Muscle Contraction Neuron Remodeling Regulation Of Binding Learning Or Memory Urinary Bladder Smooth Muscle Contraction Peptidyl-histidine Phosphorylation Regulation Of Protein Metabolic Process Regulation Of Epithelial Cell Proliferation Cognition Ribonucleotide Metabolic Process Nucleoside Metabolic Process Cellular Calcium Ion Homeostasis Nucleotide Biosynthetic Process Positive Regulation Of Glycolytic Process	Positive Regulation Of Cellular Metabolic Process Regulation Of Apoptotic Process GTP Biosynthetic Process UTP Biosynthetic Process GTP Metabolic Process UTP Metabolic Process Regulation Of Cell Death CTP Biosynthetic Process Positive Regulation Of Metabolic Process Nucleoside Diphosphate Phosphorylation Pyrimidine Ribonucleotide Biosynthetic Process Pyrimidine Nucleoside Biosynthetic Process Pyrimidine Nucleotide Biosynthetic Process Nucleotide Phosphorylation Nucleoside Diphosphate Metabolic Process Regulation Of Metabolic Process Response To Organic Cyclic Compound Pyrimidine Nucleoside Metabolic Process Regulation Of Cell Cycle Response To Hormone Pyrimidine Nucleotide Metabolic Process Cellular Response To Lipid Nucleoside Triphosphate Biosynthetic Process Nucleosome Disassembly Mitotic Cell Cycle Nucleobase-containing Small Molecule Interconversion Regulation Of Cell Cycle Process Regulation Of Cellular Protein Metabolic Process Positive Regulation Of Cell Development Response To Drug Positive Regulation Of Cell Projection Organization Response To Organic Substance Positive Regulation Of Cell Cycle Response To Lipid Ribonucleotide Metabolic Process Positive Regulation Of Mitotic Cell Cycle Purine Nucleotide Metabolic Process Ribose Phosphate Metabolic Process Regulation Of DNA Replication Regulation Of Macrophage Activation Regulation Of Protein Metabolic Process Cell Cycle Telomere Maintenance Via Telomere Lengthening Cellular Response To Organic Substance Purine Nucleotide Biosynthetic Process Cell-matrix Adhesion Ribose Phosphate Biosynthetic Process Cellular Response To Organic Cyclic Compound Regulation Of Cellular Component Organization Cellular Response To Acid Chemical
Tagcloud ?		address affecting arhgdib autonomous bcl3 concomitant deregulated dissociation erbb2 gdp intrinsic lungs malignancy mammary metalloprotease mmtv modifying motility neu nme1 nme2 oncogene oncogenic proto rescued solid timp1 timp2 turnover	17q12 anonymous brca1 cloning colia1 d17s183 dinucleotide edh17b exclude excludes families heterozygosity hox2 inherited locale ngfr nme2 ovarian phb pinpoint polymorphisms positional q21 rara recombination resolving scg43 thra1 wnt3
Tagcloud (Difference) ?		address affecting arhgdib autonomous bcl3 concomitant deregulated dissociation erbb2 gdp intrinsic lungs malignancy mammary metalloprotease mmtv modifying motility neu oncogene oncogenic proto rescued solid timp1 timp2 turnover	17q12 anonymous brca1 cloning colia1 d17s183 dinucleotide edh17b exclude excludes families heterozygosity hox2 inherited locale ngfr ovarian phb pinpoint polymorphisms positional q21 rara recombination resolving scg43 thra1 wnt3
Tagcloud (Intersection) ?		nme1 nme2