NCL and TOP1

  • Number of citations of the paper that reports this interaction (PMID 8567649)
  • 18
  • Data Source:
  • BioGRID (affinity chromatography technology)
  • HPRD (in vivo, in vitro)

NCL

TOP1

Gene Name nucleolin topoisomerase (DNA) I
Image
Gene Ontology Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Attention deficit hyperactivity disorder ( 23728934)
  • Eating disorders (purging via substances) ( 23568457)
Protein-Protein Interactions 48 interactors: ADAP1 ADAP2 CD3E CD3EAP CDK1 CDKN2A CSNK2A1 CSNK2A2 ERG ETS1 FMR1 GRB2 GZF1 GZMA H2AFX HIST1H1C HIST2H2AC HIST2H2BE HIST3H3 HMGA1 IL7R MDC1 MDK MDM2 MYB MYBL1 NBN NDRG1 NPM1 NR3C1 PARP1 PPARGC1A PPM1D PRKCZ PTGS1 S100A11 SREK1 SSB STAU1 TERF2 TERT TOP1 TP53 VHL XRCC6 YWHAQ ZFP36 ZNF689 55 interactors: APAF1 APP ATM BARD1 BTBD1 BTBD2 BUB3 CASP3 CASP6 CDK8 CKAP5 CSNK2A1 CSNK2A2 DDB2 ELK3 ERCC8 ERG FSHR GEMIN4 GRWD1 IL7R IRF4 IRF8 IRF9 JAK1 JUN KMT2A LIG4 LSM4 MDM2 NCL NCOA6 PDE10A PPP2R2B PRB1 PYGM RBL1 RBL2 RCVRN SF3B1 SFPQ SNRNP70 SNW1 SRSF1 SRSF11 SUMO1 SYMPK TARBP2 TDP1 TOPORS TP53 TRIM32 TUBD1 U2AF2 UBE2I
Entrez ID 4691 7150
HPRD ID 01245 00535
Ensembl ID ENSG00000198900
Uniprot IDs B3KM80 P19338 Q9BQ02 P11387
PDB IDs 2FC8 2FC9 2KRR 1A31 1A35 1A36 1EJ9 1K4S 1K4T 1LPQ 1NH3 1R49 1RR8 1RRJ 1SC7 1SEU 1T8I 1TL8
Enriched GO Terms of Interacting Partners?
Tagcloud ?
affinity  capping  corresponding  deletion  eif  end  eucaryotic  fold  free  germ  hairpin  initiation  interference  leader  loop  mrna  noncoding  ovalbumin  rabbit  rate  recognition  restored  reticulocyte  secondary  sequence  structure  systems  translation  wheat 
anucleate  catalytically  complements  dispensable  division  evolutionarily  homologs  hypersensitive  inviability  inviable  lethal  mitosis  permissive  pombe  probable  proper  restrictive  schizosaccharomyces  searches  semi  synthetically  thiabendazole  top1p  topoisomerase  trf4  trf4p  trf5  trf5p  ts 
Tagcloud (Difference) ?
affinity  capping  corresponding  deletion  eif  end  eucaryotic  fold  free  germ  hairpin  initiation  interference  leader  loop  mrna  noncoding  ovalbumin  rabbit  rate  recognition  restored  reticulocyte  secondary  sequence  structure  systems  translation  wheat 
anucleate  catalytically  complements  dispensable  division  evolutionarily  homologs  hypersensitive  inviability  inviable  lethal  mitosis  permissive  pombe  probable  proper  restrictive  schizosaccharomyces  searches  semi  synthetically  thiabendazole  top1p  topoisomerase  trf4  trf4p  trf5  trf5p  ts 
Tagcloud (Intersection) ?