NCL and MYBL1

Number of citations of the paper that reports this interaction (PMID 10660576)
24

Data Source:
BioGRID (affinity chromatography technology, far western blotting)
HPRD (in vitro, in vivo)

		NCL	MYBL1
Gene Name		nucleolin	v-myb avian myeloblastosis viral oncogene homolog-like 1
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Nucleoplasm Nucleolus Cell Cortex Membrane Ribonucleoprotein Complex Cytoplasmic Ribonucleoprotein Granule Extracellular Vesicular Exosome	Nucleus
	Molecular Function	Nucleotide Binding RNA Binding Protein Binding Protein C-terminus Binding Telomeric DNA Binding Identical Protein Binding Poly(A) RNA Binding	RNA Polymerase II Core Promoter Proximal Region Sequence-specific DNA Binding RNA Polymerase II Core Promoter Proximal Region Sequence-specific DNA Binding Transcription Factor Activity Involved In Positive Regulation Of Transcription Chromatin Binding
	Biological Process	Angiogenesis Positive Regulation Of Transcription Of Nuclear Large RRNA Transcript From RNA Polymerase I Promoter	Transcription, DNA-templated Gene Expression PiRNA Metabolic Process Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription From RNA Polymerase II Promoter
Pathways			PIWI-interacting RNA (piRNA) biogenesis Regulatory RNA pathways
Drugs
Diseases
GWAS		Attention deficit hyperactivity disorder ( 23728934) Eating disorders (purging via substances) ( 23568457)
Protein-Protein Interactions		48 interactors: ADAP1 ADAP2 CD3E CD3EAP CDK1 CDKN2A CSNK2A1 CSNK2A2 ERG ETS1 FMR1 GRB2 GZF1 GZMA H2AFX HIST1H1C HIST2H2AC HIST2H2BE HIST3H3 HMGA1 IL7R MDC1 MDK MDM2 MYB MYBL1 NBN NDRG1 NPM1 NR3C1 PARP1 PPARGC1A PPM1D PRKCZ PTGS1 S100A11 SREK1 SSB STAU1 TERF2 TERT TOP1 TP53 VHL XRCC6 YWHAQ ZFP36 ZNF689	4 interactors: CREBBP HIPK2 NCL NLK
Entrez ID		4691	4603
HPRD ID		01245	08868
Ensembl ID			ENSG00000185697
Uniprot IDs		B3KM80 P19338 Q9BQ02	P10243 Q495G0
PDB IDs		2FC8 2FC9 2KRR
Enriched GO Terms of Interacting Partners?		Chromosome Organization DNA Conformation Change Positive Regulation Of Metabolic Process Regulation Of Nitrogen Compound Metabolic Process Regulation Of Metabolic Process Negative Regulation Of Cellular Metabolic Process Cell Aging Positive Regulation Of Gene Expression Positive Regulation Of Cellular Metabolic Process Negative Regulation Of Cell Cycle Chromatin Organization Response To Stimulus Nucleobase-containing Compound Metabolic Process Cellular Response To Stress DNA Packaging Cellular Response To Stimulus Developmental Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Cellular Response To DNA Damage Stimulus Regulation Of Gene Expression Regulation Of Apoptotic Process Chromatin Assembly Telomere Maintenance Cellular Nitrogen Compound Metabolic Process Cell Cycle Checkpoint Regulation Of Cell Death Chromatin Assembly Or Disassembly Response To Stress Mitotic Cell Cycle Checkpoint Regulation Of Cell Proliferation DNA Metabolic Process Positive Regulation Of Macromolecule Biosynthetic Process Nitrogen Compound Metabolic Process Positive Regulation Of Cell Aging Negative Regulation Of Gene Expression Regulation Of Cell Cycle Negative Regulation Of Biosynthetic Process Aging Positive Regulation Of Cellular Biosynthetic Process Negative Regulation Of Mitotic Cell Cycle Regulation Of Cellular Process RNA Biosynthetic Process Cellular Senescence Double-strand Break Repair Protein Complex Assembly DNA Damage Checkpoint Cell Cycle Process Regulation Of RNA Metabolic Process Mitotic Cell Cycle Process	Peptidyl-threonine Phosphorylation Cellular Response To Hypoxia Cellular Response To Decreased Oxygen Levels Cellular Response To Oxygen Levels Peptidyl-serine Phosphorylation Transforming Growth Factor Beta Receptor Signaling Pathway Peptidyl-amino Acid Modification Positive Regulation Of Transcription Of Nuclear Large RRNA Transcript From RNA Polymerase I Promoter Cellular Response To Transforming Growth Factor Beta Stimulus Response To Transforming Growth Factor Beta N-terminal Peptidyl-lysine Acetylation Serine Phosphorylation Of STAT3 Protein Voluntary Musculoskeletal Movement Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Positive Regulation Of Transcription, DNA-templated PML Body Organization Serine Phosphorylation Of STAT Protein Response To Hypoxia Germ-line Stem Cell Maintenance Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Gene Expression Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Positive Regulation Of Cellular Biosynthetic Process Regulation Of RNA Metabolic Process Iris Morphogenesis Lens Induction In Camera-type Eye Positive Regulation Of Transcription From RNA Polymerase I Promoter Regulation Of Gene Expression N-terminal Protein Amino Acid Acetylation Regulation Of Nitrogen Compound Metabolic Process DNA Damage Response, Signal Transduction By P53 Class Mediator Resulting In Transcription Of P21 Class Mediator DNA Damage Response, Signal Transduction Resulting In Transcription Embryonic Retina Morphogenesis In Camera-type Eye Viral Process Regulation Of Transcription From RNA Polymerase I Promoter Transcription, DNA-templated Cellular Response To Growth Factor Stimulus Response To Growth Factor Modulation By Virus Of Host Morphology Or Physiology RNA Biosynthetic Process Anatomical Structure Morphogenesis Positive Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Regulation Of Transcription From RNA Polymerase II Promoter In Response To Hypoxia Embryonic Morphogenesis Retina Layer Formation N-terminal Protein Amino Acid Modification Positive Regulation Of Cellular Metabolic Process Lens Morphogenesis In Camera-type Eye
Tagcloud ?		affinity capping corresponding deletion eif end eucaryotic fold free germ hairpin initiation interference leader loop mrna noncoding ovalbumin rabbit rate recognition restored reticulocyte secondary sequence structure systems translation wheat	adenosarcoma appearing atrx britain cdk4 cnvs confirmation copyright diagnose exonic hmga2 interrogating introns ireland john ltd ma mdm2 mullerian overgrowth pathobiology pik3ca rearrangements sarcomatous sons stroma tools uncommon wiley
Tagcloud (Difference) ?		affinity capping corresponding deletion eif end eucaryotic fold free germ hairpin initiation interference leader loop mrna noncoding ovalbumin rabbit rate recognition restored reticulocyte secondary sequence structure systems translation wheat	adenosarcoma appearing atrx britain cdk4 cnvs confirmation copyright diagnose exonic hmga2 interrogating introns ireland john ltd ma mdm2 mullerian overgrowth pathobiology pik3ca rearrangements sarcomatous sons stroma tools uncommon wiley
Tagcloud (Intersection) ?