NCL and LINC01554

Number of citations of the paper that reports this interaction (PubMedID 30809309)
42

Data Source:
BioGRID (unspecified method)

		NCL	LINC01554
Description		nucleolin	long intergenic non-protein coding RNA 1554
Image			No pdb structure
GO Annotations	Cellular Component	Cornified Envelope Nucleus Nucleoplasm Spliceosomal Complex Chromosome Nucleolus Cytoplasm Plasma Membrane Cell Cortex Membrane Cytoplasmic Ribonucleoprotein Granule Extracellular Exosome Macropinosome Membrane Ribonucleoprotein Complex
	Molecular Function	Nucleic Acid Binding DNA Binding RNA Binding Protein Binding Telomeric DNA Binding PH Domain Binding Identical Protein Binding Insulin Receptor Substrate Binding DNA Topoisomerase Binding MRNA 5'-UTR Binding
	Biological Process	Angiogenesis Regulation Of Gene Expression Positive Regulation Of Macromolecule Biosynthetic Process Negative Regulation Of Translation Positive Regulation Of Transcription By RNA Polymerase II Negative Regulation Of Insulin Receptor Signaling Pathway Positive Regulation Of MRNA Splicing, Via Spliceosome Regulation Of RNA Metabolic Process Cellular Response To Epidermal Growth Factor Stimulus Positive Regulation Of Transcription Of Nucleolar Large RRNA By RNA Polymerase I Cellular Response To Leukemia Inhibitory Factor
Pathways		Major pathway of rRNA processing in the nucleolus and cytosol Respiratory syncytial virus (RSV) attachment and entry
Drugs
Diseases
GWAS		Appendicular lean mass ( 33097823) Attention deficit hyperactivity disorder ( 23728934) Common carotid intima-media thickness in HIV negative individuals ( 29206233) Eating disorders (purging via substances) ( 23568457) Hearing loss in noise exposure ( 26121033) Height ( 31562340) Hip index ( 34021172)	LDL cholesterol levels in HIV infection ( 33109212)
Interacting Genes		61 interacting genes: ADAP1 ADAP2 BCL2 CD3E CDK1 CDKN2A CLK1 CSNK2A1 CSNK2A2 DANCR DUX4 ERG ESR1 ETS1 FMR1 GRB2 GZF1 GZMA H1-2 H2AC20 H2AX H2BC21 H3-4 HMGA1 IL7R ISG15 LINC01554 MDC1 MDK MDM2 MYB MYBL1 NBN NDRG1 NPM1 NR3C1 OGT PARP1 PPARGC1A PPM1D PRKCZ PRMT5 PTGS1 RAD51 RNF10 S100A11 SREK1 SRPK2 SSB STAU1 SUMO2 TERF2 TERT TOP1 TP53 VHL XRCC6 YWHAQ ZFP36 ZFP41 ZNF689	141 interacting genes: AARS1 ACADVL ACIN1 ACTB ACTG1 ACTN1 ACTN3 ACTR3 ALDOA ANXA2 ANXA5 ANXA6 APEX1 ARHGAP1 ASS1 ATAD3A ATIC ATP5F1A BZW2 CANX CCT2 CCT3 CCT4 CCT6A CCT7 CKAP4 CS CTPS1 DDX3X DDX46 DHX9 DNAH2 DNAJA1 DST DYNC1H1 EDARADD EEF1G EEF2 EIF3A EIF3E EIF4A2 EIF4B ENO1 ENO3 EPRS1 ERO1A G3BP1 G6PD GANAB GAPDH GARS1 GDI2 GPI GTF2I HIVEP2 HMCN1 HNRNPF HSP90AA1 HSP90B1 HSPA1L HSPA5 HSPA8 HSPA9 HSPD1 HYOU1 IDH1 IPO4 IPO7 IPO9 ITPR2 KARS1 KPNA1 KPNB1 KRT18 KRT7 KRT8 KRT8P3 LRPPRC MCM7 MSN MYO18A NAP1L1 NAP1L4 NCBP1 NCL NPM1 OLA1 OXCT1 PABPC1 PCBP2 PDIA3 PDIA6 PFAS PGD PGK1 PGM1 PHGDH PKM PLOD2 PMPCA POR PPP2R1A PSMC1 PSMD2 PSMD7 PTBP1 RDX RPL6 RPSA RTCB RTN4 SARS1 SEPTIN7 SEPTIN9 SERPINH1 SFPQ SQSTM1 TARS1 TGFBI THOP1 TKT TTF2 TUBA1A TUBA8 TUBB TUBB2A TUBB3 TUBB4A TUBB4B TUBB6 TUFM TXNRD1 TYMP UBA1 VCL VCP VIM VPS35 WARS1 XPO1 XRCC5
Entrez ID		4691	202299
HPRD ID		01245	16896
Ensembl ID		ENSG00000115053	ENSG00000236882
Uniprot IDs		B3KM80 P19338
PDB IDs		2FC8 2FC9 2KRR
Enriched GO Terms of Interacting Partners?		Regulation Of Macromolecule Metabolic Process Regulation Of Metabolic Process Nucleus Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of Primary Metabolic Process Regulation Of Macromolecule Biosynthetic Process Regulation Of Gene Expression Positive Regulation Of Macromolecule Metabolic Process Response To Stress Chromatin Organization Positive Regulation Of Metabolic Process Negative Regulation Of Macromolecule Metabolic Process Nucleoplasm Negative Regulation Of Metabolic Process Chromosome DNA Damage Response Regulation Of Cell Population Proliferation Cellular Response To Stress Positive Regulation Of Macromolecule Biosynthetic Process Regulation Of Programmed Cell Death Positive Regulation Of Biosynthetic Process Signal Transduction In Response To DNA Damage Positive Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of Apoptotic Process Protein Localization To Site Of Double-strand Break Protein Localization To Organelle DNA Binding Chromosome, Telomeric Region Regulation Of RNA Metabolic Process Chromatin Remodeling Response To Gamma Radiation Negative Regulation Of Macromolecule Biosynthetic Process Regulation Of DNA Recombination Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process Response To Ionizing Radiation Negative Regulation Of Biosynthetic Process Negative Regulation Of Cell Cycle Regulation Of Cell Cycle Process DNA Metabolic Process Protein Localization To Chromosome Negative Regulation Of Nucleobase-containing Compound Metabolic Process Nucleic Acid Metabolic Process Regulation Of DNA Metabolic Process Regulation Of Transcription By RNA Polymerase II Regulation Of Cell Cycle Positive Regulation Of Gene Expression DNA Repair Negative Regulation Of DNA Metabolic Process Macromolecule Metabolic Process	Extracellular Exosome RNA Binding Nucleotide Binding Cytosol Cytoplasm Unfolded Protein Binding ATP-dependent Protein Folding Chaperone ATP Hydrolysis Activity ATP Binding Focal Adhesion Protein Folding Secretory Granule Lumen Cadherin Binding Ficolin-1-rich Granule Lumen Protein Folding Chaperone Structural Constituent Of Cytoskeleton Nucleotide Metabolic Process Nicotinamide Nucleotide Metabolic Process Microtubule Ubiquitin Protein Ligase Binding Nucleobase-containing Compound Metabolic Process Ligase Activity Melanosome Purine Nucleotide Metabolic Process Nucleoside Phosphate Metabolic Process Protein Refolding Nucleobase-containing Small Molecule Metabolic Process Glycolytic Process Positive Regulation Of Telomerase RNA Localization To Cajal Body Ribose Phosphate Metabolic Process ADP Catabolic Process Positive Regulation Of Protein Localization To Cajal Body Chaperonin-containing T-complex ATP Metabolic Process Purine Ribonucleoside Diphosphate Catabolic Process Ribonucleoprotein Complex Ribonucleoside Diphosphate Catabolic Process ADP Metabolic Process Nucleotide Catabolic Process Nucleoside Diphosphate Catabolic Process TRNA Aminoacylation For Protein Translation Aminoacyl-tRNA Ligase Activity Ribonucleotide Metabolic Process Microtubule Cytoskeleton Protein Folding In Endoplasmic Reticulum Regulation Of Telomerase RNA Localization To Cajal Body Positive Regulation Of Telomere Maintenance Via Telomerase Nucleobase-containing Compound Catabolic Process Translation TRNA Aminoacylation
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