MYBPC1 and FHL1

Number of citations of the paper that reports this interaction (PMID 16407297)
24

Data Source:
BioGRID (pull down)
HPRD (in vivo, two hybrid, in vitro)

		MYBPC1	FHL1
Gene Name		myosin binding protein C, slow type	four and a half LIM domains 1
Image
Gene Ontology Annotations	Cellular Component	Cytosol Myofibril Myosin Filament	Nucleus Cytoplasm Cytosol Plasma Membrane Focal Adhesion
	Molecular Function	Actin Binding Protein Binding Structural Constituent Of Muscle Titin Binding	Molecular_function Protein Binding Zinc Ion Binding Ion Channel Binding
	Biological Process	Cell Adhesion Muscle Filament Sliding	Regulation Of Membrane Depolarization Muscle Organ Development Organ Morphogenesis Negative Regulation Of G2/M Transition Of Mitotic Cell Cycle Cell Differentiation Negative Regulation Of Cell Growth Positive Regulation Of Potassium Ion Transport Regulation Of Potassium Ion Transmembrane Transporter Activity Negative Regulation Of G1/S Transition Of Mitotic Cell Cycle
Pathways		Striated Muscle Contraction
Drugs
Diseases
GWAS
Protein-Protein Interactions		10 interactors: CALM1 FHL1 FHL2 FHL3 MEOX2 NCF1 RAF1 TRIM55 TRIM63 TTN	19 interactors: AKAP12 CBX4 DBN1 DEAF1 EED FHL2 HES1 HIVEP3 MYBPC1 PDE4DIP PRNP RBPJ RING1 SRF SRPK1 TTN TXNIP UBE2E2 USP15
Entrez ID		4604	2273
HPRD ID		01185	02157
Ensembl ID		ENSG00000196091	ENSG00000022267
Uniprot IDs		A8KAB1 B3KPP3 Q00872 Q86TA8	B7Z9A1 Q13642
PDB IDs		1X44 2DAV 2YUV 2YUW 2YUX 2YUZ 2YXM	1X63 2CUP 2CUR 2EGQ
Enriched GO Terms of Interacting Partners?		Muscle Structure Development Muscle Organ Development Vascular Endothelial Growth Factor Receptor Signaling Pathway Organ Development Activation Of Adenylate Cyclase Activity Platelet Activation Muscle Contraction Positive Regulation Of Adenylate Cyclase Activity Muscle System Process Positive Regulation Of Lyase Activity Regulation Of Adenylate Cyclase Activity Striated Muscle Tissue Development Positive Regulation Of CAMP Biosynthetic Process Muscle Tissue Development Cardiovascular System Development Regulation Of Cyclase Activity Positive Regulation Of CAMP Metabolic Process Cardiac Muscle Cell Development System Development Platelet Degranulation Response To Hormone Death-inducing Signaling Complex Assembly Positive Regulation Of Cyclic Nucleotide Metabolic Process Regulation Of CAMP Biosynthetic Process Blood Coagulation Hemostasis Response To Abiotic Stimulus Regulation Of CAMP Metabolic Process Neutrophil Mediated Killing Of Gram-positive Bacterium Neutrophil Mediated Killing Of Fungus Multicellular Organismal Development Cardiac Muscle Cell Differentiation Reactive Oxygen Species Metabolic Process Anatomical Structure Development Heart Development Response To Calcium Ion Skeletal Muscle Myosin Thick Filament Assembly Atrial Cardiac Muscle Cell Development Sarcomerogenesis Detection Of Muscle Stretch Cardiocyte Differentiation Regulation Of Body Fluid Levels Regulation Of Ion Transmembrane Transporter Activity Regulation Of Transmembrane Transporter Activity Directional Locomotion Response To Electrical Stimulus Involved In Regulation Of Muscle Adaptation Positive Regulation Of Cyclic-nucleotide Phosphodiesterase Activity Wound Healing Anatomical Structure Morphogenesis Response To Glucocorticoid	Cardiocyte Differentiation Heart Morphogenesis Aorta Morphogenesis Negative Regulation Of Transcription, DNA-templated Heart Trabecula Morphogenesis Aorta Development Regulation Of Nitrogen Compound Metabolic Process Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Muscle Structure Development Transcription, DNA-templated Regulation Of RNA Metabolic Process Striated Muscle Tissue Development Negative Regulation Of Gene Expression RNA Biosynthetic Process Muscle Cell Differentiation Cardiac Chamber Development Negative Regulation Of Biosynthetic Process Muscle Tissue Development Trabecula Morphogenesis RNA Metabolic Process Auditory Receptor Cell Fate Commitment Dorsal Aorta Morphogenesis Regulation Of Gene Expression Muscle Cell Development Artery Morphogenesis Dorsal Aorta Development Cell Differentiation Negative Regulation Of Cellular Metabolic Process Cardiac Muscle Tissue Development Gene Expression Regulation Of Transcription From RNA Polymerase II Promoter Involved In Myocardial Precursor Cell Differentiation Regulation Of Transcription, DNA-templated Artery Development Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Cardiac Muscle Cell Development Tissue Development Regulation Of Metabolic Process Cardiac Muscle Cell Myoblast Differentiation Nucleobase-containing Compound Metabolic Process Cell Development Heart Development Regulation Of Transcription From RNA Polymerase II Promoter Cardioblast Differentiation Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Anatomical Structure Development Heart Trabecula Formation Cellular Nitrogen Compound Metabolic Process
Tagcloud ?		ankrd2 annotation besides breed breeds dctn1 deg duroc est explaining giving grouped helpful libraries listed meat myl2 myogenesis neb novels piau pig postnatal prenatal prenatally tags transcriptome uncovering vertebrates	764g atrophy biopsy bodies boy cardiomyopathy distal dreifuss dystrophy echocardiogram emery exon hemizygous hypertrophic linked missense muscle muscular myopathy occurring pathology postural predominantly reducing scapuloperoneal sequencing vacuolar wasting weakness
Tagcloud (Difference) ?		ankrd2 annotation besides breed breeds dctn1 deg duroc est explaining giving grouped helpful libraries listed meat myl2 myogenesis neb novels piau pig postnatal prenatal prenatally tags transcriptome uncovering vertebrates	764g atrophy biopsy bodies boy cardiomyopathy distal dreifuss dystrophy echocardiogram emery exon hemizygous hypertrophic linked missense muscle muscular myopathy occurring pathology postural predominantly reducing scapuloperoneal sequencing vacuolar wasting weakness
Tagcloud (Intersection) ?