MYBPC1 and KLHL41

Number of citations of the paper that reports this interaction (PubMedID 23414517)
48

Data Source:
BioGRID (two hybrid)

		MYBPC1	KLHL41
Description		myosin binding protein C1	kelch like family member 41
Image			No pdb structure
GO Annotations	Cellular Component	Cytosol Myofibril M Band Myosin Filament	Ruffle Nucleoplasm Cytoplasm Endoplasmic Reticulum Endoplasmic Reticulum Membrane Cytosol Cytoskeleton Plasma Membrane Membrane Sarcoplasmic Reticulum Pseudopodium M Band Cul3-RING Ubiquitin Ligase Complex Sarcoplasmic Reticulum Membrane Cell Projection
	Molecular Function	Actin Binding Protein Binding Structural Constituent Of Muscle Myosin Binding Titin Binding	Protein Binding Ubiquitin-like Ligase-substrate Adaptor Activity
	Biological Process	Cell Adhesion Sarcomere Organization	Striated Muscle Contraction Protein Ubiquitination Myofibril Assembly Skeletal Muscle Cell Differentiation Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Regulation Of Myoblast Differentiation Regulation Of Myoblast Proliferation Regulation Of Skeletal Muscle Cell Differentiation
Pathways		Striated Muscle Contraction	Neddylation Antigen processing: Ubiquitination & Proteasome degradation
Drugs
Diseases
GWAS		Lung function (FEV1) ( 24023788) Memory decline ( 31985465)
Interacting Genes		27 interacting genes: ACO1 AMOT ANKRD1 ASH2L C1QTNF9 CALM1 CAPN3 CLIP4 DNAJB5 DNAJB6 DYSF FHL1 FHL2 FHL3 GABARAP GABARAPL1 GABARAPL2 KLHL41 MAP1LC3A MEOX2 MYBPC2 NCF1 RAF1 SGCG TRIM55 TRIM63 TTN	9 interacting genes: IFRD1 MYBPC1 NRAP POMP RBM4 RCHY1 SLC2A4 SPMIP2 TCAP
Entrez ID		4604	10324
HPRD ID		01185	07610
Ensembl ID		ENSG00000196091	ENSG00000239474
Uniprot IDs		A8KAB1 B3KPP3 Q00872	O60662
PDB IDs		1X44 2DAV 2YUV 2YUW 2YUX 2YUZ 2YXM
Enriched GO Terms of Interacting Partners?		Cellular Response To Nitrogen Starvation Titin Binding Phosphatidylethanolamine Binding Actin Cytoskeleton Organization Z Disc M Band Cytoskeleton Organization Actin Filament-based Process Sarcomere Organization Actomyosin Structure Organization Autophagosome Maturation Phospholipid Binding Autophagosome Membrane Mitophagy GABA Receptor Binding Autophagy Of Mitochondrion Organelle Organization Autophagosome Response To Muscle Stretch Myofibril Assembly Autophagosome Assembly Autophagosome Organization Adenylate Cyclase Activator Activity Beta-tubulin Binding Structural Constituent Of Muscle Muscle Organ Development Response To Iron(II) Ion Muscle Structure Development Protein-containing Complex Disassembly Organelle Assembly Cytoplasm Macroautophagy Response To Metal Ion Vacuole Organization Microtubule Cellular Response To Starvation Pseudopodium Response To Starvation Cellular Response To Nutrient Levels Cytosol I Band Supramolecular Fiber Organization Response To Iron Ion Autophagy Response To Calcium Ion Ubiquitin Protein Ligase Binding Anatomical Structure Formation Involved In Morphogenesis Protein Binding Calcium-dependent Self Proteolysis Monocyte Activation Involved In Immune Response	Titin Binding
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