MYBPC1 and TTN

Number of citations of the paper that reports this interaction (PMID 1429890)
21

Data Source:
HPRD (in vitro)

		MYBPC1	TTN
Gene Name		myosin binding protein C, slow type	titin
Image
Gene Ontology Annotations	Cellular Component	Cytosol Myofibril Myosin Filament	Condensed Nuclear Chromosome Extracellular Region Cytosol Striated Muscle Thin Filament Z Disc M Band I Band Extracellular Vesicular Exosome
	Molecular Function	Actin Binding Protein Binding Structural Constituent Of Muscle Titin Binding	Protease Binding Protein Serine/threonine Kinase Activity Protein Tyrosine Kinase Activity Calcium Ion Binding Protein Binding Calmodulin Binding ATP Binding Structural Constituent Of Muscle Enzyme Binding Protein Kinase Binding Telethonin Binding Identical Protein Binding Actinin Binding Protein Self-association Actin Filament Binding Muscle Alpha-actinin Binding Structural Molecule Activity Conferring Elasticity
	Biological Process	Cell Adhesion Muscle Filament Sliding	Platelet Degranulation Cardiac Muscle Hypertrophy Muscle Contraction Striated Muscle Contraction Mitotic Chromosome Condensation Blood Coagulation Peptidyl-tyrosine Phosphorylation Muscle Filament Sliding Platelet Activation Skeletal Muscle Thin Filament Assembly Skeletal Muscle Myosin Thick Filament Assembly Detection Of Muscle Stretch Sarcomere Organization Regulation Of Protein Kinase Activity Cardiac Muscle Fiber Development Sarcomerogenesis Regulation Of Catalytic Activity Response To Calcium Ion Cardiac Myofibril Assembly Cardiac Muscle Tissue Morphogenesis Cardiac Muscle Contraction
Pathways		Striated Muscle Contraction	Striated Muscle Contraction Response to elevated platelet cytosolic Ca2+ Platelet degranulation Platelet activation, signaling and aggregation
Drugs
Diseases
GWAS			Breast size ( 22747683) QT interval ( 20031603)
Protein-Protein Interactions		10 interactors: CALM1 FHL1 FHL2 FHL3 MEOX2 NCF1 RAF1 TRIM55 TRIM63 TTN	29 interactors: ACTA1 ACTN1 ACTN2 ANK1 ANKRD1 ANKRD2 ANKRD23 CALM1 CAPN3 CRYAB FHL1 FHL2 FLNA MAPK1 MYBPC1 MYBPC3 MYH9 MYOM1 MYOM2 MYPN NBR1 NEB OBSCN SQSTM1 SRPK2 TCAP TRIM55 TRIM63 VAV2
Entrez ID		4604	7273
HPRD ID		01185	01787
Ensembl ID		ENSG00000196091	ENSG00000155657
Uniprot IDs		A8KAB1 B3KPP3 Q00872 Q86TA8	Q7Z3B7 Q8WZ42
PDB IDs		1X44 2DAV 2YUV 2YUW 2YUX 2YUZ 2YXM	1BPV 1G1C 1NCT 1NCU 1TIT 1TIU 1TKI 1TNM 1TNN 1WAA 1YA5 2A38 2BK8 2F8V 2ILL 2J8H 2J8O 2NZI 2RQ8 2WP3 2WWK 2WWM 2Y9R 3B43 3KNB 3LCY 3LPW 3PUC 3Q5O 3QP3
Enriched GO Terms of Interacting Partners?		Muscle Structure Development Muscle Organ Development Vascular Endothelial Growth Factor Receptor Signaling Pathway Organ Development Activation Of Adenylate Cyclase Activity Platelet Activation Muscle Contraction Positive Regulation Of Adenylate Cyclase Activity Muscle System Process Positive Regulation Of Lyase Activity Regulation Of Adenylate Cyclase Activity Striated Muscle Tissue Development Positive Regulation Of CAMP Biosynthetic Process Muscle Tissue Development Cardiovascular System Development Regulation Of Cyclase Activity Positive Regulation Of CAMP Metabolic Process Cardiac Muscle Cell Development System Development Platelet Degranulation Response To Hormone Death-inducing Signaling Complex Assembly Positive Regulation Of Cyclic Nucleotide Metabolic Process Regulation Of CAMP Biosynthetic Process Blood Coagulation Hemostasis Response To Abiotic Stimulus Regulation Of CAMP Metabolic Process Neutrophil Mediated Killing Of Gram-positive Bacterium Neutrophil Mediated Killing Of Fungus Multicellular Organismal Development Cardiac Muscle Cell Differentiation Reactive Oxygen Species Metabolic Process Anatomical Structure Development Heart Development Response To Calcium Ion Skeletal Muscle Myosin Thick Filament Assembly Atrial Cardiac Muscle Cell Development Sarcomerogenesis Detection Of Muscle Stretch Cardiocyte Differentiation Regulation Of Body Fluid Levels Regulation Of Ion Transmembrane Transporter Activity Regulation Of Transmembrane Transporter Activity Directional Locomotion Response To Electrical Stimulus Involved In Regulation Of Muscle Adaptation Positive Regulation Of Cyclic-nucleotide Phosphodiesterase Activity Wound Healing Anatomical Structure Morphogenesis Response To Glucocorticoid	Muscle Contraction Muscle System Process Muscle Structure Development Actin Filament-based Process Actomyosin Structure Organization Actin Filament-based Movement Actin-myosin Filament Sliding Muscle Filament Sliding Myofibril Assembly Striated Muscle Cell Differentiation Striated Muscle Cell Development Actin-mediated Cell Contraction Muscle Cell Development Sarcomere Organization Muscle Organ Development Muscle Cell Differentiation Cellular Component Assembly Actin Cytoskeleton Organization Anatomical Structure Formation Involved In Morphogenesis Anatomical Structure Morphogenesis Cytoskeleton Organization Platelet Activation Cell Differentiation Cell Development Organelle Assembly Developmental Process Anatomical Structure Development Organ Development Blood Coagulation Hemostasis System Development Multicellular Organismal Development Platelet Degranulation Striated Muscle Tissue Development Response To Stress Muscle Tissue Development Response To Abiotic Stimulus Regulation Of Apoptotic Process Response To External Stimulus Regulation Of Body Fluid Levels Organelle Organization Neurotrophin TRK Receptor Signaling Pathway Movement Of Cell Or Subcellular Component Response To Stimulus Wound Healing Cardiovascular System Development Neurotrophin Signaling Pathway Regulation Of Cell Death Regulation Of Intracellular Transport Cell Activation
Tagcloud ?		ankrd2 annotation besides breed breeds dctn1 deg duroc est explaining giving grouped helpful libraries listed meat myl2 myogenesis neb novels piau pig postnatal prenatal prenatally tags transcriptome uncovering vertebrates	amounts anticancer atlas braf broad diverse exome frequencies frequency frg1b harbored includes integrated lineage metastastic muc16 mutated mutational obtain omics pbrm1 resource sequencing somatic subtypes summarized ush2a varied vhl
Tagcloud (Difference) ?		ankrd2 annotation besides breed breeds dctn1 deg duroc est explaining giving grouped helpful libraries listed meat myl2 myogenesis neb novels piau pig postnatal prenatal prenatally tags transcriptome uncovering vertebrates	amounts anticancer atlas braf broad diverse exome frequencies frequency frg1b harbored includes integrated lineage metastastic muc16 mutated mutational obtain omics pbrm1 resource sequencing somatic subtypes summarized ush2a varied vhl
Tagcloud (Intersection) ?