MYBPC1 and FHL3

Number of citations of the paper that reports this interaction (PMID 16407297)
24

Data Source:
BioGRID (two hybrid, affinity chromatography technology)

		MYBPC1	FHL3
Gene Name		myosin binding protein C, slow type	four and a half LIM domains 3
Image
Gene Ontology Annotations	Cellular Component	Cytosol Myofibril Myosin Filament	Stress Fiber Nucleus Focal Adhesion Z Disc
	Molecular Function	Actin Binding Protein Binding Structural Constituent Of Muscle Titin Binding	Actin Binding Zinc Ion Binding
	Biological Process	Cell Adhesion Muscle Filament Sliding	Muscle Organ Development Actin Cytoskeleton Organization
Pathways		Striated Muscle Contraction
Drugs
Diseases
GWAS
Protein-Protein Interactions		10 interactors: CALM1 FHL1 FHL2 FHL3 MEOX2 NCF1 RAF1 TRIM55 TRIM63 TTN	88 interactors: A1CF ACTB ADAM15 ADAMTSL4 AIMP2 AMBP C14orf105 C9orf116 CDC25B CDC42EP1 CNNM3 CORO1A CSF1 CTBP2 DCDC2B E2F8 EFCAB12 EPHA10 EPM2AIP1 FAM154A FAM71C FAM90A1 FBXL18 FHL2 FHL5 FOSL2 GATA2 GCM2 HIPK1 HYAL2 ITGA7 KIRREL2 KLF3 KLF8 KRTAP12-1 KRTAP12-2 KTI12 LASP1 LMO2 LNX1 MAPK1 MED15 MPZL1 MRPL27 MYBPC1 MYBPHL MZF1 NPRL3 P4HA2 PAK7 PATL1 PHC2 PHF21A PLEKHF2 PPIG PTPN6 QRICH1 RAD21 RBM42 RFX3 RFX6 RHEBL1 RNMTL1 SAP30BP SLAIN1 SLC25A46 SLC44A3 SMAD2 SMAD3 SMAD4 SNRPG SREBF2 SRF TMX3 TRAF3IP2 TRIM27 TRIP6 TRO TTLL10 TYK2 TYMSOS UBE2I UBE2Q1 WNK1 YPEL3 ZNF417 ZNF512B ZNRD1
Entrez ID		4604	2275
HPRD ID		01185	09101
Ensembl ID		ENSG00000196091	ENSG00000183386
Uniprot IDs		A8KAB1 B3KPP3 Q00872 Q86TA8	Q13643 Q96C98
PDB IDs		1X44 2DAV 2YUV 2YUW 2YUX 2YUZ 2YXM	1WYH 2CUQ 2EHE
Enriched GO Terms of Interacting Partners?		Muscle Structure Development Muscle Organ Development Vascular Endothelial Growth Factor Receptor Signaling Pathway Organ Development Activation Of Adenylate Cyclase Activity Platelet Activation Muscle Contraction Positive Regulation Of Adenylate Cyclase Activity Muscle System Process Positive Regulation Of Lyase Activity Regulation Of Adenylate Cyclase Activity Striated Muscle Tissue Development Positive Regulation Of CAMP Biosynthetic Process Muscle Tissue Development Cardiovascular System Development Regulation Of Cyclase Activity Positive Regulation Of CAMP Metabolic Process Cardiac Muscle Cell Development System Development Platelet Degranulation Response To Hormone Death-inducing Signaling Complex Assembly Positive Regulation Of Cyclic Nucleotide Metabolic Process Regulation Of CAMP Biosynthetic Process Blood Coagulation Hemostasis Response To Abiotic Stimulus Regulation Of CAMP Metabolic Process Neutrophil Mediated Killing Of Gram-positive Bacterium Neutrophil Mediated Killing Of Fungus Multicellular Organismal Development Cardiac Muscle Cell Differentiation Reactive Oxygen Species Metabolic Process Anatomical Structure Development Heart Development Response To Calcium Ion Skeletal Muscle Myosin Thick Filament Assembly Atrial Cardiac Muscle Cell Development Sarcomerogenesis Detection Of Muscle Stretch Cardiocyte Differentiation Regulation Of Body Fluid Levels Regulation Of Ion Transmembrane Transporter Activity Regulation Of Transmembrane Transporter Activity Directional Locomotion Response To Electrical Stimulus Involved In Regulation Of Muscle Adaptation Positive Regulation Of Cyclic-nucleotide Phosphodiesterase Activity Wound Healing Anatomical Structure Morphogenesis Response To Glucocorticoid	RNA Metabolic Process Transcription, DNA-templated Gene Expression RNA Biosynthetic Process Cellular Macromolecule Biosynthetic Process Heterocycle Metabolic Process Macromolecule Biosynthetic Process Regulation Of Transcription From RNA Polymerase II Promoter Nitrogen Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Cellular Aromatic Compound Metabolic Process Nucleobase-containing Compound Metabolic Process Regulation Of Gene Expression Transcription From RNA Polymerase II Promoter Regulation Of Metabolic Process Regulation Of RNA Metabolic Process Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process SMAD Protein Complex Assembly Positive Regulation Of Transcription, DNA-templated Negative Regulation Of Gene Expression Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Nitrogen Compound Metabolic Process Positive Regulation Of Gene Expression Regulation Of Cellular Process Biosynthetic Process Positive Regulation Of Cellular Biosynthetic Process Cellular Metabolic Process Negative Regulation Of Cellular Metabolic Process Cell Differentiation Negative Regulation Of Transcription From RNA Polymerase II Promoter Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Nucleic Acid-templated Transcription Regulation Of Cell Proliferation Negative Regulation Of RNA Biosynthetic Process Tissue Development Positive Regulation Of Cellular Metabolic Process Cell Death Death Multicellular Organismal Homeostasis Positive Regulation Of Epithelial To Mesenchymal Transition Endoderm Development Negative Regulation Of Cell Growth Embryonic Organ Development Positive Regulation Of Metabolic Process Primary MiRNA Processing Organ Development Apoptotic Process
Tagcloud ?		ankrd2 annotation besides breed breeds dctn1 deg duroc est explaining giving grouped helpful libraries listed meat myl2 myogenesis neb novels piau pig postnatal prenatal prenatally tags transcriptome uncovering vertebrates	accompanied adhesion anchorage antiproliferative arrest b1 cip1 downregulated g1 g2 half implicated interfering knockdown lim marked marker member mobility p21 progression regulator sirna suppressed thereby transduction unclear waf1
Tagcloud (Difference) ?		ankrd2 annotation besides breed breeds dctn1 deg duroc est explaining giving grouped helpful libraries listed meat myl2 myogenesis neb novels piau pig postnatal prenatal prenatally tags transcriptome uncovering vertebrates	accompanied adhesion anchorage antiproliferative arrest b1 cip1 downregulated g1 g2 half implicated interfering knockdown lim marked marker member mobility p21 progression regulator sirna suppressed thereby transduction unclear waf1
Tagcloud (Intersection) ?