MSH2 and ATR

  • Number of citations of the paper that reports this interaction (PMID 14657349)
  • 58
  • Data Source:
  • BioGRID (imaging technique)
  • HPRD (in vivo, in vitro)

MSH2

ATR

Gene Name mutS homolog 2 ATR serine/threonine kinase
Image No pdb structure
Gene Ontology Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions 25 interactors: ANXA7 ATR BARD1 BRCA1 CDKN1A CHEK2 CREBBP ESR1 ESR2 EXO1 GRB7 HUS1 MAX MSH3 MSH6 PCNA RAD1 RAD9A RPA4 RPP14 SMC1A SMN1 TK1 TREX1 XPA 47 interactors: AATF ABL1 AP1B1 AP2A2 ARHGEF1 ATM ATRIP BLM BRCA1 BRCA2 CDKN2C CEP164 CHD4 CHEK1 CHEK2 CLSPN CREB1 DCLRE1C DTL E2F1 E4F1 EEF1E1 EP300 FANCA FANCD2 FLT1 H2AFX KDR LIG4 MCM2 MRE11A MSH2 NBN PA2G4 PIK3CA POLD1 POLN PPP2R2A PTS RAD17 RHEB TP53 TREX1 UPF1 VPRBP XPA XRCC5
Entrez ID 4436 545
HPRD ID 00389 08369
Ensembl ID ENSG00000095002 ENSG00000175054
Uniprot IDs E9PHA6 P43246 Q13535
PDB IDs 2O8B 2O8C 2O8D 2O8E 2O8F 3THW 3THX 3THY 3THZ
Enriched GO Terms of Interacting Partners?
Tagcloud ?
adapter  autophosphorylation  catalytic  cloned  competed  designated  glutathione  gst  immunoprecipitated  inactive  involve  ir  ir1316  ir1322  ir950  ir960  juxtamembrane  mitogenic  motifs  participate  phosphopeptides  raised  representing  similarity  strictly  transferase  tyr  unidentified 
activators  breakage  broad  chromatin  chromosome  comprises  concept  defect  discuss  emerging  exert  heterochromatin  hybrid  inherited  mediate  member  modulating  mr  numerous  observations  remodelling  repair  retardation  seems  segregation  snf2  somehow  thalaessemia  xnp 
Tagcloud (Difference) ?
adapter  autophosphorylation  catalytic  cloned  competed  designated  glutathione  gst  immunoprecipitated  inactive  involve  ir  ir1316  ir1322  ir950  ir960  juxtamembrane  mitogenic  motifs  participate  phosphopeptides  raised  representing  similarity  strictly  transferase  tyr  unidentified 
activators  breakage  broad  chromatin  chromosome  comprises  concept  defect  discuss  emerging  exert  heterochromatin  hybrid  inherited  mediate  member  modulating  mr  numerous  observations  remodelling  repair  retardation  seems  segregation  snf2  somehow  thalaessemia  xnp 
Tagcloud (Intersection) ?