ARVCF and ERBB2IP

Number of citations of the paper that reports this interaction (PMID 11821434)
35

Data Source:
HPRD (in vivo, in vitro)

		ARVCF	ERBB2IP
Gene Name		armadillo repeat gene deleted in velocardiofacial syndrome	erbb2 interacting protein
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Intracellular Nucleoplasm Cytoplasm Plasma Membrane Cell Junction	Basement Membrane Nucleus Nucleoplasm Cytoplasm Plasma Membrane Basal Plasma Membrane Cell Junction Hemidesmosome Nuclear Membrane
	Molecular Function	Protein Binding	ErbB-2 Class Receptor Binding Integrin Binding Structural Constituent Of Cytoskeleton Protein Binding
	Biological Process	Cell Adhesion Multicellular Organismal Development Single Organismal Cell-cell Adhesion Calcium-dependent Cell-cell Adhesion Via Plasma Membrane Cell Adhesion Molecules	Protein Targeting Cell Cycle Cell Adhesion Signal Transduction Epidermal Growth Factor Receptor Signaling Pathway Integrin-mediated Signaling Pathway Cell Growth Intermediate Filament Cytoskeleton Organization Basal Protein Localization Establishment Or Maintenance Of Epithelial Cell Apical/basal Polarity
Pathways			Signaling by ERBB2
Drugs
Diseases
GWAS		Platelet counts ( 22139419)
Protein-Protein Interactions		6 interactors: CDH1 CDH15 CDH2 ERBB2IP LNX1 TJP1	62 interactors: ABCA1 ABCC4 ABR ACTN1 ACTN2 ACVR2A ACVR2B AGTR2 APC ARHGEF7 ARVCF ATP2B1 ATP2B2 ATP2B4 BANF1 CASK CDH1 CHUK COPB1 CTNNB1 CTNND1 CTNND2 CTSG DLG4 DST ERBB2 FOXO3 GRIN2B GRIN2C GUCY1A2 ITGB4 KCNA4 KCNA5 LAMB1 LMO1 LMO2 LRRC1 MAP4 MAPK12 MCC MEF2A MPP1 MPP2 MPP3 NOD2 NR2E1 PICK1 PKP4 RAF1 SCN4A SHOC2 SLC5A5 SLC5A6 SLC6A12 SMAD1 SMAD2 SMAD3 SMAD4 SMAD7 STAT3 VIPR2 ZFYVE9
Entrez ID		421	55914
HPRD ID		03778	06090
Ensembl ID		ENSG00000099889	ENSG00000112851
Uniprot IDs		E9PDC3 O00192	B4DIP2 Q96RT1
PDB IDs			1MFG 1MFL 1N7T 2H3L 2QBW 3CH8
Enriched GO Terms of Interacting Partners?		Cell Junction Assembly Cell-cell Junction Organization Adherens Junction Organization Homophilic Cell Adhesion Via Plasma Membrane Adhesion Molecules Cellular Component Assembly Cell-cell Adhesion Via Plasma-membrane Adhesion Molecules Cell-cell Adhesion Calcium-dependent Cell-cell Adhesion Via Plasma Membrane Cell Adhesion Molecules Blastocyst Formation Cell Adhesion Cellular Component Disassembly Involved In Execution Phase Of Apoptosis Execution Phase Of Apoptosis Positive Regulation Of Muscle Cell Differentiation Cell-cell Signaling Involved In Cell-cell Junction Organization Blastocyst Development Cell-cell Junction Assembly Basal Protein Localization Negative Regulation Of Canonical Wnt Signaling Pathway Regulation Of Muscle Cell Differentiation Sensory Perception Of Sound Cell-cell Adhesion Mediated By Cadherin Sensory Perception Of Mechanical Stimulus Response To Magnetism Negative Regulation Of Wnt Signaling Pathway Epithelial Cell Development Cellular Response To Indole-3-methanol Regulation Of Canonical Wnt Signaling Pathway Activation Of Anaphase-promoting Complex Activity Establishment Of Endothelial Intestinal Barrier Protein Homooligomerization Salivary Gland Cavitation Regulation Of Wnt Signaling Pathway Muscle Cell Differentiation Negative Regulation Of Vascular Permeability Negative Regulation Of Cell Aging Regulation Of Branching Involved In Salivary Gland Morphogenesis Intestinal Epithelial Cell Development Cellular Response To Lithium Ion Protein Oligomerization Regulation Of Cell Differentiation Cell Differentiation Regulation Of Protein Localization To Cell Surface Regulation Of Water Loss Via Skin Establishment Or Maintenance Of Epithelial Cell Apical/basal Polarity Intestinal Epithelial Cell Differentiation Neuronal Stem Cell Maintenance Protein K11-linked Ubiquitination Ubiquitin-dependent Protein Catabolic Process Muscle Structure Development Modification-dependent Protein Catabolic Process	Regulation Of Signaling Response To Stimulus Response To Organic Substance Signaling Cellular Response To Growth Factor Stimulus Cell Communication Response To Growth Factor Cellular Response To Organic Substance Enzyme Linked Receptor Protein Signaling Pathway Positive Regulation Of Metabolic Process Regulation Of Signal Transduction Response To Stress Positive Regulation Of Cellular Metabolic Process Cellular Response To Stimulus Positive Regulation Of Cellular Biosynthetic Process Cell Junction Assembly Regulation Of Cell Proliferation SMAD Protein Complex Assembly Negative Regulation Of Cell Proliferation Cell Surface Receptor Signaling Pathway Regulation Of Cellular Component Movement Signal Transduction Cellular Response To Organic Cyclic Compound Organ Development Anatomical Structure Morphogenesis Cellular Component Assembly Cell-cell Junction Organization Positive Regulation Of Transcription, DNA-templated Renal System Development Negative Regulation Of Signaling Regulation Of Cell Motility Gastrulation Cell-cell Signaling Regulation Of Cell Differentiation Negative Regulation Of Signal Transduction Regulation Of Locomotion Response To Wounding Urogenital System Development Regulation Of Cell Migration System Development Regulation Of Epithelial Cell Proliferation Adherens Junction Organization Positive Regulation Of Macromolecule Biosynthetic Process Intracellular Signal Transduction Multicellular Organismal Development Positive Regulation Of Transcription From RNA Polymerase II Promoter Kidney Development Positive Regulation Of Gene Expression Response To Organic Cyclic Compound Neurotrophin TRK Receptor Signaling Pathway
Tagcloud ?		anagen bulb bulbs coil coiled confined desmoplakin elongated encoded enter epidermis exons faithfully follicles fused galactosidase hair infundibulum kazrin keratinocyte morphogenetic movements obvious parakeratotic periplakin reside shape widespread xenopus	adoptive cd4 cholangiocarcinoma contained exists exomic experienced harnessed helper humans infiltrating interacting lymphocytes mediate metastatic mount mutated mutation polyfunctional prolonged pure recognizing regression retreated sequencing stabilization til transfer
Tagcloud (Difference) ?		anagen bulb bulbs coil coiled confined desmoplakin elongated encoded enter epidermis exons faithfully follicles fused galactosidase hair infundibulum kazrin keratinocyte morphogenetic movements obvious parakeratotic periplakin reside shape widespread xenopus	adoptive cd4 cholangiocarcinoma contained exists exomic experienced harnessed helper humans infiltrating interacting lymphocytes mediate metastatic mount mutated mutation polyfunctional prolonged pure recognizing regression retreated sequencing stabilization til transfer
Tagcloud (Intersection) ?