ERBB2IP and MAP4

Number of citations of the paper that reports this interaction (PMID 15123239)
9

Data Source:
BioGRID (unspecified method)

		ERBB2IP	MAP4
Gene Name		erbb2 interacting protein	microtubule-associated protein 4
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Basement Membrane Nucleus Nucleoplasm Cytoplasm Plasma Membrane Basal Plasma Membrane Cell Junction Hemidesmosome Nuclear Membrane	Cytoplasm Microtubule Microtubule Associated Complex Plasma Membrane Microtubule Cytoskeleton Extracellular Vesicular Exosome Mitotic Spindle
	Molecular Function	ErbB-2 Class Receptor Binding Integrin Binding Structural Constituent Of Cytoskeleton Protein Binding	Structural Molecule Activity Protein Binding Microtubule Binding Poly(A) RNA Binding
	Biological Process	Protein Targeting Cell Cycle Cell Adhesion Signal Transduction Epidermal Growth Factor Receptor Signaling Pathway Integrin-mediated Signaling Pathway Cell Growth Intermediate Filament Cytoskeleton Organization Basal Protein Localization Establishment Or Maintenance Of Epithelial Cell Apical/basal Polarity	Mitotic Spindle Organization Microtubule Sliding Establishment Of Spindle Orientation Cell Division
Pathways		Signaling by ERBB2
Drugs
Diseases
GWAS			Blood pressure ( 21909110)
Protein-Protein Interactions		62 interactors: ABCA1 ABCC4 ABR ACTN1 ACTN2 ACVR2A ACVR2B AGTR2 APC ARHGEF7 ARVCF ATP2B1 ATP2B2 ATP2B4 BANF1 CASK CDH1 CHUK COPB1 CTNNB1 CTNND1 CTNND2 CTSG DLG4 DST ERBB2 FOXO3 GRIN2B GRIN2C GUCY1A2 ITGB4 KCNA4 KCNA5 LAMB1 LMO1 LMO2 LRRC1 MAP4 MAPK12 MCC MEF2A MPP1 MPP2 MPP3 NOD2 NR2E1 PICK1 PKP4 RAF1 SCN4A SHOC2 SLC5A5 SLC5A6 SLC6A12 SMAD1 SMAD2 SMAD3 SMAD4 SMAD7 STAT3 VIPR2 ZFYVE9	16 interactors: CCNB1 CDK1 ENO2 ERBB2IP GSK3B IL7R LDLR MARK1 MARK4 NR1I3 POT1 RXRB RXRG SNTA1 TERF1 TUBB
Entrez ID		55914	4134
HPRD ID		06090	01141
Ensembl ID		ENSG00000112851	ENSG00000047849
Uniprot IDs		B4DIP2 Q96RT1	E7EVA0 P27816
PDB IDs		1MFG 1MFL 1N7T 2H3L 2QBW 3CH8
Enriched GO Terms of Interacting Partners?		Regulation Of Signaling Response To Stimulus Response To Organic Substance Signaling Cellular Response To Growth Factor Stimulus Cell Communication Response To Growth Factor Cellular Response To Organic Substance Enzyme Linked Receptor Protein Signaling Pathway Positive Regulation Of Metabolic Process Regulation Of Signal Transduction Response To Stress Positive Regulation Of Cellular Metabolic Process Cellular Response To Stimulus Positive Regulation Of Cellular Biosynthetic Process Cell Junction Assembly Regulation Of Cell Proliferation SMAD Protein Complex Assembly Negative Regulation Of Cell Proliferation Cell Surface Receptor Signaling Pathway Regulation Of Cellular Component Movement Signal Transduction Cellular Response To Organic Cyclic Compound Organ Development Anatomical Structure Morphogenesis Cellular Component Assembly Cell-cell Junction Organization Positive Regulation Of Transcription, DNA-templated Renal System Development Negative Regulation Of Signaling Regulation Of Cell Motility Gastrulation Cell-cell Signaling Regulation Of Cell Differentiation Negative Regulation Of Signal Transduction Regulation Of Locomotion Response To Wounding Urogenital System Development Regulation Of Cell Migration System Development Regulation Of Epithelial Cell Proliferation Adherens Junction Organization Positive Regulation Of Macromolecule Biosynthetic Process Intracellular Signal Transduction Multicellular Organismal Development Positive Regulation Of Transcription From RNA Polymerase II Promoter Kidney Development Positive Regulation Of Gene Expression Response To Organic Cyclic Compound Neurotrophin TRK Receptor Signaling Pathway	G2/M Transition Of Mitotic Cell Cycle Mitotic Cell Cycle Phase Transition Cell Cycle Phase Transition Ventricular Cardiac Muscle Cell Differentiation Negative Regulation Of Telomere Maintenance Via Telomerase Cell Cycle Striated Muscle Cell Differentiation Muscle Structure Development Telomere Maintenance Via Telomerase Negative Regulation Of Telomere Maintenance Negative Regulation Of Telomerase Activity Regulation Of Telomere Maintenance Via Telomerase Positive Regulation Of Gene Expression Cell Cycle Process Positive Regulation Of Cellular Biosynthetic Process Steroid Hormone Mediated Signaling Pathway Regulation Of Telomerase Activity Regulation Of Nitrogen Compound Metabolic Process Striated Muscle Tissue Development Muscle Cell Differentiation Cardiac Muscle Cell Differentiation Muscle Tissue Development Mitotic Cell Cycle Process Positive Regulation Of Mitotic Cell Cycle Peptidyl-serine Phosphorylation Ventricular Cardiac Muscle Cell Development Regulation Of Telomere Maintenance Regulation Of DNA Replication Cardiocyte Differentiation Hormone-mediated Signaling Pathway RNA-dependent DNA Replication Mitotic Cell Cycle Positive Regulation Of Cellular Metabolic Process Cellular Response To Organic Substance Regulation Of Protein Catabolic Process Positive Regulation Of Metabolic Process Negative Regulation Of DNA Biosynthetic Process Cellular Response To Organic Cyclic Compound Positive Regulation Of Proteolysis Involved In Cellular Protein Catabolic Process Positive Regulation Of Organelle Organization Positive Regulation Of Cellular Protein Catabolic Process Cellular Response To Lipid Positive Regulation Of Developmental Growth Cell Division G1/S Transition Of Mitotic Cell Cycle Retinoic Acid Receptor Signaling Pathway Response To Stimulus Epidermal Growth Factor Receptor Signaling Pathway ERBB Signaling Pathway Transcription Initiation From RNA Polymerase II Promoter
Tagcloud ?		adoptive cd4 cholangiocarcinoma contained exists exomic experienced harnessed helper humans infiltrating interacting lymphocytes mediate metastatic mount mutated mutation polyfunctional prolonged pure recognizing regression retreated sequencing stabilization til transfer	brefeldin constructs dextran dic distributions golgi impacts inducibly mock morphogenesis motility movements mt mts organellar organelle overexpress overexpressed polarization repositioning retarded stabilization stabilize stabilized steady taxol transferrin unusual vesicle
Tagcloud (Difference) ?		adoptive cd4 cholangiocarcinoma contained exists exomic experienced harnessed helper humans infiltrating interacting lymphocytes mediate metastatic mount mutated mutation polyfunctional prolonged pure recognizing regression retreated sequencing til transfer	brefeldin constructs dextran dic distributions golgi impacts inducibly mock morphogenesis motility movements mt mts organellar organelle overexpress overexpressed polarization repositioning retarded stabilize stabilized steady taxol transferrin unusual vesicle
Tagcloud (Intersection) ?		stabilization