ERBB2IP and ATP2B1

Number of citations of the paper that reports this interaction (PMID 15123239)
9

Data Source:
BioGRID (unspecified method)

		ERBB2IP	ATP2B1
Gene Name		erbb2 interacting protein	ATPase, Ca++ transporting, plasma membrane 1
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Basement Membrane Nucleus Nucleoplasm Cytoplasm Plasma Membrane Basal Plasma Membrane Cell Junction Hemidesmosome Nuclear Membrane	Nucleus Plasma Membrane Integral Component Of Plasma Membrane Membrane Extracellular Vesicular Exosome
	Molecular Function	ErbB-2 Class Receptor Binding Integrin Binding Structural Constituent Of Cytoskeleton Protein Binding	Calcium-transporting ATPase Activity Protein Binding Calmodulin Binding ATP Binding Metal Ion Binding
	Biological Process	Protein Targeting Cell Cycle Cell Adhesion Signal Transduction Epidermal Growth Factor Receptor Signaling Pathway Integrin-mediated Signaling Pathway Cell Growth Intermediate Filament Cytoskeleton Organization Basal Protein Localization Establishment Or Maintenance Of Epithelial Cell Apical/basal Polarity	Transport Blood Coagulation Metabolic Process Ion Transmembrane Transport Transmembrane Transport Calcium Ion Transmembrane Transport
Pathways		Signaling by ERBB2	Ion transport by P-type ATPases Ion channel transport Platelet homeostasis Reduction of cytosolic Ca++ levels Platelet calcium homeostasis
Drugs
Diseases
GWAS			Biomedical quantitative traits ( 19396169) Blood pressure ( 21572416 21909110) Coronary heart disease ( 22751097) Diastolic blood pressure ( 19430479) Hypertension ( 19430479) Magnesium levels ( 20700443) Systolic blood pressure ( 19430479)
Protein-Protein Interactions		62 interactors: ABCA1 ABCC4 ABR ACTN1 ACTN2 ACVR2A ACVR2B AGTR2 APC ARHGEF7 ARVCF ATP2B1 ATP2B2 ATP2B4 BANF1 CASK CDH1 CHUK COPB1 CTNNB1 CTNND1 CTNND2 CTSG DLG4 DST ERBB2 FOXO3 GRIN2B GRIN2C GUCY1A2 ITGB4 KCNA4 KCNA5 LAMB1 LMO1 LMO2 LRRC1 MAP4 MAPK12 MCC MEF2A MPP1 MPP2 MPP3 NOD2 NR2E1 PICK1 PKP4 RAF1 SCN4A SHOC2 SLC5A5 SLC5A6 SLC6A12 SMAD1 SMAD2 SMAD3 SMAD4 SMAD7 STAT3 VIPR2 ZFYVE9	5 interactors: CALM1 CSNK2A1 ERBB2IP PRKACA PRKCA
Entrez ID		55914	490
HPRD ID		06090	00158
Ensembl ID		ENSG00000112851	ENSG00000070961
Uniprot IDs		B4DIP2 Q96RT1	P20020
PDB IDs		1MFG 1MFL 1N7T 2H3L 2QBW 3CH8
Enriched GO Terms of Interacting Partners?		Regulation Of Signaling Response To Stimulus Response To Organic Substance Signaling Cellular Response To Growth Factor Stimulus Cell Communication Response To Growth Factor Cellular Response To Organic Substance Enzyme Linked Receptor Protein Signaling Pathway Positive Regulation Of Metabolic Process Regulation Of Signal Transduction Response To Stress Positive Regulation Of Cellular Metabolic Process Cellular Response To Stimulus Positive Regulation Of Cellular Biosynthetic Process Cell Junction Assembly Regulation Of Cell Proliferation SMAD Protein Complex Assembly Negative Regulation Of Cell Proliferation Cell Surface Receptor Signaling Pathway Regulation Of Cellular Component Movement Signal Transduction Cellular Response To Organic Cyclic Compound Organ Development Anatomical Structure Morphogenesis Cellular Component Assembly Cell-cell Junction Organization Positive Regulation Of Transcription, DNA-templated Renal System Development Negative Regulation Of Signaling Regulation Of Cell Motility Gastrulation Cell-cell Signaling Regulation Of Cell Differentiation Negative Regulation Of Signal Transduction Regulation Of Locomotion Response To Wounding Urogenital System Development Regulation Of Cell Migration System Development Regulation Of Epithelial Cell Proliferation Adherens Junction Organization Positive Regulation Of Macromolecule Biosynthetic Process Intracellular Signal Transduction Multicellular Organismal Development Positive Regulation Of Transcription From RNA Polymerase II Promoter Kidney Development Positive Regulation Of Gene Expression Response To Organic Cyclic Compound Neurotrophin TRK Receptor Signaling Pathway	Epidermal Growth Factor Receptor Signaling Pathway ERBB Signaling Pathway Regulation Of Rhodopsin Mediated Signaling Pathway Activation Of Adenylate Cyclase Activity Rhodopsin Mediated Signaling Pathway Positive Regulation Of Adenylate Cyclase Activity Positive Regulation Of Dense Core Granule Biogenesis Positive Regulation Of Lyase Activity Activation Of Phospholipase C Activity Histone H3-T6 Phosphorylation Regulation Of Adenylate Cyclase Activity Positive Regulation Of Phospholipase C Activity Positive Regulation Of CAMP Biosynthetic Process Regulation Of Cyclase Activity Positive Regulation Of CAMP Metabolic Process Positive Regulation Of Phospholipase Activity Phototransduction, Visible Light Positive Regulation Of Cyclic Nucleotide Metabolic Process Regulation Of Phospholipase Activity Regulation Of CAMP Biosynthetic Process Positive Regulation Of Lipase Activity Detection Of Visible Light Cellular Response To Light Stimulus Phototransduction Regulation Of CAMP Metabolic Process Vascular Endothelial Growth Factor Receptor Signaling Pathway Peptidyl-serine Autophosphorylation Positive Regulation Of Lipopolysaccharide-mediated Signaling Pathway Detection Of Light Stimulus Desmosome Assembly Negative Regulation Of Glial Cell Apoptotic Process Energy Reserve Metabolic Process Cellular Response To Radiation Negative Regulation Of Glucose Import Positive Regulation Of Macrophage Differentiation Regulation Of Muscle Contraction Desmosome Organization Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Fibroblast Growth Factor Receptor Signaling Pathway Regulation Of Heart Contraction Regulation Of G-protein Coupled Receptor Protein Signaling Pathway Detection Of Abiotic Stimulus Cellular Response To Fibroblast Growth Factor Stimulus Regulation Of Cardiac Muscle Contraction By Regulation Of The Release Of Sequestered Calcium Ion Negative Regulation Of Glucose Transport Regulation Of Platelet Aggregation Response To Fibroblast Growth Factor Platelet Activation Induction Of Positive Chemotaxis Positive Regulation Of Cardiac Muscle Hypertrophy
Tagcloud ?		adoptive cd4 cholangiocarcinoma contained exists exomic experienced harnessed helper humans infiltrating interacting lymphocytes mediate metastatic mount mutated mutation polyfunctional prolonged pure recognizing regression retreated sequencing stabilization til transfer	aggregated aggregately ancestry bp cacnb2 conditioning consortium cyp17a1 dbp epidemiology gwas harbor individually intronic jag1 ld maf plekha7 pp rs11191416 rs112467382 rs12806040 rs1571787 rs6163 rs743572 sbp sh2b3 snp strongest
Tagcloud (Difference) ?		adoptive cd4 cholangiocarcinoma contained exists exomic experienced harnessed helper humans infiltrating interacting lymphocytes mediate metastatic mount mutated mutation polyfunctional prolonged pure recognizing regression retreated sequencing stabilization til transfer	aggregated aggregately ancestry bp cacnb2 conditioning consortium cyp17a1 dbp epidemiology gwas harbor individually intronic jag1 ld maf plekha7 pp rs11191416 rs112467382 rs12806040 rs1571787 rs6163 rs743572 sbp sh2b3 snp strongest
Tagcloud (Intersection) ?