ARVCF and TJP1

Number of citations of the paper that reports this interaction (PMID 15456900)
24

Data Source:
HPRD (in vivo, in vitro, two hybrid)

		ARVCF	TJP1
Gene Name		armadillo repeat gene deleted in velocardiofacial syndrome	tight junction protein 1
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Intracellular Nucleoplasm Cytoplasm Plasma Membrane Cell Junction	Nucleus Cytoplasm Cytosol Plasma Membrane Cell-cell Adherens Junction Gap Junction Tight Junction Intercalated Disc Basolateral Plasma Membrane Apical Plasma Membrane Apicolateral Plasma Membrane Cell Junction Apical Junction Complex Apical Part Of Cell Intercellular Canaliculus
	Molecular Function	Protein Binding	Protein Binding Calmodulin Binding Protein C-terminus Binding Protein Domain Specific Binding
	Biological Process	Cell Adhesion Multicellular Organismal Development Single Organismal Cell-cell Adhesion Calcium-dependent Cell-cell Adhesion Via Plasma Membrane Cell Adhesion Molecules	Blastocyst Formation Apoptotic Process Cellular Component Disassembly Involved In Execution Phase Of Apoptosis Cell-cell Junction Assembly Sensory Perception Of Sound Response To Lipopolysaccharide Hippo Signaling Response To Drug Negative Regulation Of Vascular Permeability Response To Ethanol Membrane Organization Response To Magnetism Cellular Response To Glucose Stimulus Establishment Of Endothelial Intestinal Barrier Cell-cell Signaling Involved In Cell-cell Junction Organization
Pathways			Apoptotic cleavage of cell adhesion proteins c-src mediated regulation of Cx43 function and closure of gap junctions Apoptotic cleavage of cellular proteins Signaling by Hippo Gap junction trafficking and regulation Programmed Cell Death Apoptotic execution phase Regulation of gap junction activity
Drugs
Diseases
GWAS		Platelet counts ( 22139419)	Corneal structure ( 23291589) Response to antipsychotic treatment ( 23241943)
Protein-Protein Interactions		6 interactors: CDH1 CDH15 CDH2 ERBB2IP LNX1 TJP1	38 interactors: ACTA1 ACTN4 ARVCF CGN CLDN1 CLDN16 CLDN2 CLDN3 CLDN4 CLDN5 CLDN6 CLDN7 CLDN8 CNKSR2 CTNNA1 CTTN EGFR F11R GJA1 GJA3 GJA8 GJB3 GJC1 GJD3 GRIN1 GRIN2D HSP90AA1 JAM2 JAM3 KHDRBS1 KIRREL MLLT4 PTPN14 TJP2 TJP3 TRPC4 UBN1 YBX3
Entrez ID		421	7082
HPRD ID		03778	03002
Ensembl ID		ENSG00000099889	ENSG00000104067
Uniprot IDs		E9PDC3 O00192	G3V1L9 Q07157 Q6MZU1
PDB IDs			2H2B 2H2C 2H3M 2JWE 2KXR 2KXS 2RCZ 3CYY 3LH5 3SHU 3SHW 3TSV 3TSW 3TSZ
Enriched GO Terms of Interacting Partners?		Cell Junction Assembly Cell-cell Junction Organization Adherens Junction Organization Homophilic Cell Adhesion Via Plasma Membrane Adhesion Molecules Cellular Component Assembly Cell-cell Adhesion Via Plasma-membrane Adhesion Molecules Cell-cell Adhesion Calcium-dependent Cell-cell Adhesion Via Plasma Membrane Cell Adhesion Molecules Blastocyst Formation Cell Adhesion Cellular Component Disassembly Involved In Execution Phase Of Apoptosis Execution Phase Of Apoptosis Positive Regulation Of Muscle Cell Differentiation Cell-cell Signaling Involved In Cell-cell Junction Organization Blastocyst Development Cell-cell Junction Assembly Basal Protein Localization Negative Regulation Of Canonical Wnt Signaling Pathway Regulation Of Muscle Cell Differentiation Sensory Perception Of Sound Cell-cell Adhesion Mediated By Cadherin Sensory Perception Of Mechanical Stimulus Response To Magnetism Negative Regulation Of Wnt Signaling Pathway Epithelial Cell Development Cellular Response To Indole-3-methanol Regulation Of Canonical Wnt Signaling Pathway Activation Of Anaphase-promoting Complex Activity Establishment Of Endothelial Intestinal Barrier Protein Homooligomerization Salivary Gland Cavitation Regulation Of Wnt Signaling Pathway Muscle Cell Differentiation Negative Regulation Of Vascular Permeability Negative Regulation Of Cell Aging Regulation Of Branching Involved In Salivary Gland Morphogenesis Intestinal Epithelial Cell Development Cellular Response To Lithium Ion Protein Oligomerization Regulation Of Cell Differentiation Cell Differentiation Regulation Of Protein Localization To Cell Surface Regulation Of Water Loss Via Skin Establishment Or Maintenance Of Epithelial Cell Apical/basal Polarity Intestinal Epithelial Cell Differentiation Neuronal Stem Cell Maintenance Protein K11-linked Ubiquitination Ubiquitin-dependent Protein Catabolic Process Muscle Structure Development Modification-dependent Protein Catabolic Process	Calcium-independent Cell-cell Adhesion Via Plasma Membrane Cell-adhesion Molecules Cell-cell Junction Organization Cell Adhesion Cell-cell Adhesion Via Plasma-membrane Adhesion Molecules Cell-cell Adhesion Cell Junction Assembly Cell-cell Junction Assembly Gap Junction Assembly Cell Development Establishment Of Endothelial Intestinal Barrier Anatomical Structure Development Cellular Component Assembly Developmental Process Epithelial Cell Development Apical Junction Assembly Establishment Of Endothelial Barrier Endothelium Development Neuron Projection Development Regulation Of Body Fluid Levels Response To Abiotic Stimulus Regulation Of Actin Filament-based Process Anatomical Structure Morphogenesis Tight Junction Assembly Transmembrane Transport Endothelial Cell Development Response To Organic Substance System Development Movement Of Cell Or Subcellular Component Neuron Development Cell Differentiation Atrial Cardiac Muscle Cell Action Potential Atrial Cardiac Muscle Cell To AV Node Cell Communication Multicellular Organismal Development Locomotion Cell Communication Single Organismal Cell-cell Adhesion Epithelial Cell Differentiation Cell Morphogenesis Axon Development Endothelial Cell Differentiation Neuron Differentiation Cell-cell Signaling Involved In Cardiac Conduction Cell Projection Organization Positive Regulation Of Rap GTPase Activity Neurological System Process Establishment Of Skin Barrier Adherens Junction Organization Skin Development Neuron Projection Morphogenesis Cell-cell Signaling
Tagcloud ?		anagen bulb bulbs coil coiled confined desmoplakin elongated encoded enter epidermis exons faithfully follicles fused galactosidase hair infundibulum kazrin keratinocyte morphogenetic movements obvious parakeratotic periplakin reside shape widespread xenopus	abp androgen ar blots clonal clu constitutes fshr hampering immortalized immunocytochemistry inhbb investigations loose mediators microarrays posttranslational responsiveness rhox5 sc sertoli sox9 spermatogenesis spinlw1 st38c stabilization testosterone undergoes wt1
Tagcloud (Difference) ?		anagen bulb bulbs coil coiled confined desmoplakin elongated encoded enter epidermis exons faithfully follicles fused galactosidase hair infundibulum kazrin keratinocyte morphogenetic movements obvious parakeratotic periplakin reside shape widespread xenopus	abp androgen ar blots clonal clu constitutes fshr hampering immortalized immunocytochemistry inhbb investigations loose mediators microarrays posttranslational responsiveness rhox5 sc sertoli sox9 spermatogenesis spinlw1 st38c stabilization testosterone undergoes wt1
Tagcloud (Intersection) ?