ERBB2IP and ATP2B4

Number of citations of the paper that reports this interaction (PMID 15123239)
9

Data Source:
BioGRID (unspecified method)

		ERBB2IP	ATP2B4
Gene Name		erbb2 interacting protein	ATPase, Ca++ transporting, plasma membrane 4
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Gene Ontology Annotations	Cellular Component	Basement Membrane Nucleus Nucleoplasm Cytoplasm Plasma Membrane Basal Plasma Membrane Cell Junction Hemidesmosome Nuclear Membrane	Plasma Membrane Integral Component Of Plasma Membrane Caveola Membrane Z Disc T-tubule Protein Complex
	Molecular Function	ErbB-2 Class Receptor Binding Integrin Binding Structural Constituent Of Cytoskeleton Protein Binding	Calcium-transporting ATPase Activity Protein Binding Calmodulin Binding ATP Binding Sodium Channel Regulator Activity Protein Phosphatase 2B Binding Nitric-oxide Synthase Inhibitor Activity Metal Ion Binding Nitric-oxide Synthase Binding Scaffold Protein Binding
	Biological Process	Protein Targeting Cell Cycle Cell Adhesion Signal Transduction Epidermal Growth Factor Receptor Signaling Pathway Integrin-mediated Signaling Pathway Cell Growth Intermediate Filament Cytoskeleton Organization Basal Protein Localization Establishment Or Maintenance Of Epithelial Cell Apical/basal Polarity	Regulation Of Transcription From RNA Polymerase II Promoter Cellular Calcium Ion Homeostasis Blood Coagulation Metabolic Process Negative Regulation Of Nitric Oxide Mediated Signal Transduction Positive Regulation Of Peptidyl-serine Phosphorylation Ion Transmembrane Transport Negative Regulation Of Nitric Oxide Biosynthetic Process Negative Regulation Of Nitric-oxide Synthase Activity Response To Hydrostatic Pressure Calcium Ion Homeostasis Transmembrane Transport Calcium Ion Transmembrane Transport Negative Regulation Of Calcineurin-NFAT Signaling Cascade Cellular Response To Epinephrine Stimulus Calcium Ion Import Across Plasma Membrane Negative Regulation Of The Force Of Heart Contraction Negative Regulation Of Arginine Catabolic Process Negative Regulation Of Adrenergic Receptor Signaling Pathway Involved In Heart Process Negative Regulation Of Peptidyl-cysteine S-nitrosylation Regulation Of Sodium Ion Transmembrane Transport Negative Regulation Of Cardiac Muscle Hypertrophy In Response To Stress Negative Regulation Of Citrulline Biosynthetic Process Positive Regulation Of CAMP-dependent Protein Kinase Activity
Pathways		Signaling by ERBB2	Ion transport by P-type ATPases Ion channel transport Platelet homeostasis Reduction of cytosolic Ca++ levels Platelet calcium homeostasis
Drugs
Diseases
GWAS			Breast size ( 22747683) Malaria ( 22895189) Mean corpuscular hemoglobin concentration ( 23263863)
Protein-Protein Interactions		62 interactors: ABCA1 ABCC4 ABR ACTN1 ACTN2 ACVR2A ACVR2B AGTR2 APC ARHGEF7 ARVCF ATP2B1 ATP2B2 ATP2B4 BANF1 CASK CDH1 CHUK COPB1 CTNNB1 CTNND1 CTNND2 CTSG DLG4 DST ERBB2 FOXO3 GRIN2B GRIN2C GUCY1A2 ITGB4 KCNA4 KCNA5 LAMB1 LMO1 LMO2 LRRC1 MAP4 MAPK12 MCC MEF2A MPP1 MPP2 MPP3 NOD2 NR2E1 PICK1 PKP4 RAF1 SCN4A SHOC2 SLC5A5 SLC5A6 SLC6A12 SMAD1 SMAD2 SMAD3 SMAD4 SMAD7 STAT3 VIPR2 ZFYVE9	11 interactors: CASK CD22 DLG1 DLG2 DLG3 DLG4 ERBB2IP NOS1 PPP3CA RASSF1 SRC
Entrez ID		55914	493
HPRD ID		06090	00159
Ensembl ID		ENSG00000112851	ENSG00000058668
Uniprot IDs		B4DIP2 Q96RT1	P23634
PDB IDs		1MFG 1MFL 1N7T 2H3L 2QBW 3CH8	1CFF 2KNE
Enriched GO Terms of Interacting Partners?		Regulation Of Signaling Response To Stimulus Response To Organic Substance Signaling Cellular Response To Growth Factor Stimulus Cell Communication Response To Growth Factor Cellular Response To Organic Substance Enzyme Linked Receptor Protein Signaling Pathway Positive Regulation Of Metabolic Process Regulation Of Signal Transduction Response To Stress Positive Regulation Of Cellular Metabolic Process Cellular Response To Stimulus Positive Regulation Of Cellular Biosynthetic Process Cell Junction Assembly Regulation Of Cell Proliferation SMAD Protein Complex Assembly Negative Regulation Of Cell Proliferation Cell Surface Receptor Signaling Pathway Regulation Of Cellular Component Movement Signal Transduction Cellular Response To Organic Cyclic Compound Organ Development Anatomical Structure Morphogenesis Cellular Component Assembly Cell-cell Junction Organization Positive Regulation Of Transcription, DNA-templated Renal System Development Negative Regulation Of Signaling Regulation Of Cell Motility Gastrulation Cell-cell Signaling Regulation Of Cell Differentiation Negative Regulation Of Signal Transduction Regulation Of Locomotion Response To Wounding Urogenital System Development Regulation Of Cell Migration System Development Regulation Of Epithelial Cell Proliferation Adherens Junction Organization Positive Regulation Of Macromolecule Biosynthetic Process Intracellular Signal Transduction Multicellular Organismal Development Positive Regulation Of Transcription From RNA Polymerase II Promoter Kidney Development Positive Regulation Of Gene Expression Response To Organic Cyclic Compound Neurotrophin TRK Receptor Signaling Pathway	Receptor Localization To Synapse Nucleotide Phosphorylation Protein Localization To Synapse Establishment Or Maintenance Of Apical/basal Cell Polarity Receptor Clustering Establishment Or Maintenance Of Epithelial Cell Apical/basal Polarity Establishment Or Maintenance Of Cell Polarity Nucleotide Metabolic Process Synaptic Transmission Cell Adhesion Nucleobase-containing Small Molecule Metabolic Process Positive Regulation Of Transport Cellular Protein Localization Protein Localization To Membrane Axon Guidance Membrane Organization Negative Regulation Of Hydrolase Activity Regulation Of Ion Transmembrane Transport Cell-cell Signaling Organophosphate Metabolic Process Cortical Actin Cytoskeleton Organization Axonogenesis Phosphorylation Phosphate-containing Compound Metabolic Process Cortical Cytoskeleton Organization Signaling Protein Localization Positive Regulation Of Ion Transport Axon Development Cell Communication Negative Regulation Of Cell Adhesion Cell Morphogenesis Involved In Neuron Differentiation Chemotaxis Regulation Of Sodium Ion Transmembrane Transport Regulation Of Ion Transport Negative Regulation Of Cell-matrix Adhesion Locomotion Neuron Projection Morphogenesis Cell Cycle Regulation Of Membrane Potential Cell Morphogenesis Involved In Differentiation Positive Regulation Of Metabolic Process Negative Regulation Of Cell-substrate Adhesion Small Molecule Metabolic Process Anatomical Structure Development Regulation Of Catalytic Activity Myotube Differentiation Regulation Of Phosphorus Metabolic Process Cellular Localization Regulation Of Synaptic Transmission
Tagcloud ?		adoptive cd4 cholangiocarcinoma contained exists exomic experienced harnessed helper humans infiltrating interacting lymphocytes mediate metastatic mount mutated mutation polyfunctional prolonged pure recognizing regression retreated sequencing stabilization til transfer
Tagcloud (Difference) ?		adoptive cd4 cholangiocarcinoma contained exists exomic experienced harnessed helper humans infiltrating interacting lymphocytes mediate metastatic mount mutated mutation polyfunctional prolonged pure recognizing regression retreated sequencing stabilization til transfer
Tagcloud (Intersection) ?