ARVCF and CDH2

Number of citations of the paper that reports this interaction (PMID 11058098)
9

Data Source:
HPRD (in vivo, in vitro)

		ARVCF	CDH2
Gene Name		armadillo repeat gene deleted in velocardiofacial syndrome	cadherin 2, type 1, N-cadherin (neuronal)
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Intracellular Nucleoplasm Cytoplasm Plasma Membrane Cell Junction	Plasma Membrane Cell-cell Junction Cell-cell Adherens Junction Fascia Adherens Focal Adhesion Intercalated Disc Integral Component Of Membrane Apical Plasma Membrane Catenin Complex Lamellipodium Synapse Extracellular Vesicular Exosome
	Molecular Function	Protein Binding	Calcium Ion Binding Protein Binding Beta-catenin Binding Protein Phosphatase Binding Alpha-catenin Binding Gamma-catenin Binding
	Biological Process	Cell Adhesion Multicellular Organismal Development Single Organismal Cell-cell Adhesion Calcium-dependent Cell-cell Adhesion Via Plasma Membrane Cell Adhesion Molecules	Cell Adhesion Homophilic Cell Adhesion Via Plasma Membrane Adhesion Molecules Heterophilic Cell-cell Adhesion Via Plasma Membrane Cell Adhesion Molecules Glial Cell Differentiation Calcium-dependent Cell-cell Adhesion Via Plasma Membrane Cell Adhesion Molecules Cell Migration Cell Junction Assembly Adherens Junction Organization Muscle Cell Differentiation Positive Regulation Of MAPK Cascade Cell-cell Adhesion Mediated By Cadherin Cell-cell Junction Organization Blood Vessel Morphogenesis Striated Muscle Cell Differentiation Positive Regulation Of Muscle Cell Differentiation Negative Regulation Of Canonical Wnt Signaling Pathway Neuronal Stem Cell Maintenance
Pathways			Cell junction organization Cell-cell junction organization CDO in myogenesis Myogenesis Adherens junctions interactions
Drugs
Diseases
GWAS		Platelet counts ( 22139419)	Obesity-related traits ( 23251661) Temperament (bipolar disorder) ( 22365631) vWF and FVIII levels ( 21810271)
Protein-Protein Interactions		6 interactors: CDH1 CDH15 CDH2 ERBB2IP LNX1 TJP1	22 interactors: ARHGAP32 ARVCF BOC CDH11 CDH4 CDON CREBBP CTNNA1 CTNNB1 CTNND2 EXOC5 FGFR4 GNA12 GNA13 GRIK2 GRIN1 GRIN2D JUP LRRC7 PIK3R1 PKP4 PTPN1
Entrez ID		421	1000
HPRD ID		03778	00226
Ensembl ID		ENSG00000099889	ENSG00000170558
Uniprot IDs		E9PDC3 O00192	A8MWK3 P19022
PDB IDs
Enriched GO Terms of Interacting Partners?		Cell Junction Assembly Cell-cell Junction Organization Adherens Junction Organization Homophilic Cell Adhesion Via Plasma Membrane Adhesion Molecules Cellular Component Assembly Cell-cell Adhesion Via Plasma-membrane Adhesion Molecules Cell-cell Adhesion Calcium-dependent Cell-cell Adhesion Via Plasma Membrane Cell Adhesion Molecules Blastocyst Formation Cell Adhesion Cellular Component Disassembly Involved In Execution Phase Of Apoptosis Execution Phase Of Apoptosis Positive Regulation Of Muscle Cell Differentiation Cell-cell Signaling Involved In Cell-cell Junction Organization Blastocyst Development Cell-cell Junction Assembly Basal Protein Localization Negative Regulation Of Canonical Wnt Signaling Pathway Regulation Of Muscle Cell Differentiation Sensory Perception Of Sound Cell-cell Adhesion Mediated By Cadherin Sensory Perception Of Mechanical Stimulus Response To Magnetism Negative Regulation Of Wnt Signaling Pathway Epithelial Cell Development Cellular Response To Indole-3-methanol Regulation Of Canonical Wnt Signaling Pathway Activation Of Anaphase-promoting Complex Activity Establishment Of Endothelial Intestinal Barrier Protein Homooligomerization Salivary Gland Cavitation Regulation Of Wnt Signaling Pathway Muscle Cell Differentiation Negative Regulation Of Vascular Permeability Negative Regulation Of Cell Aging Regulation Of Branching Involved In Salivary Gland Morphogenesis Intestinal Epithelial Cell Development Cellular Response To Lithium Ion Protein Oligomerization Regulation Of Cell Differentiation Cell Differentiation Regulation Of Protein Localization To Cell Surface Regulation Of Water Loss Via Skin Establishment Or Maintenance Of Epithelial Cell Apical/basal Polarity Intestinal Epithelial Cell Differentiation Neuronal Stem Cell Maintenance Protein K11-linked Ubiquitination Ubiquitin-dependent Protein Catabolic Process Muscle Structure Development Modification-dependent Protein Catabolic Process	Cellular Response To Indole-3-methanol Adherens Junction Organization Cell Junction Assembly Cell-cell Junction Organization Cell Adhesion Regulation Of Signaling Cell Surface Receptor Signaling Pathway Signaling Cell Communication Signal Transduction Multicellular Organismal Development Regulation Of Signal Transduction Positive Regulation Of Muscle Cell Differentiation Anatomical Structure Morphogenesis Cellular Response To Organonitrogen Compound Regulation Of Cell Differentiation Single Organismal Cell-cell Adhesion Developmental Process Response To Organonitrogen Compound Cellular Response To Stimulus Cell Differentiation Anatomical Structure Development Ionotropic Glutamate Receptor Signaling Pathway Synaptic Transmission, Glutamatergic Regulation Of Muscle Cell Differentiation Response To Stimulus Regulation Of Cellular Component Organization Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Glutamate Receptor Signaling Pathway Movement Of Cell Or Subcellular Component Platelet Activation Neuron-neuron Synaptic Transmission Embryonic Digit Morphogenesis Regulation Of Cell Morphogenesis Regulation Of Neural Precursor Cell Proliferation Locomotion Regulation Of Intracellular Signal Transduction Epithelial Cell-cell Adhesion Cell-cell Junction Assembly Enzyme Linked Receptor Protein Signaling Pathway Axon Development Cell-cell Signaling Vascular Endothelial Growth Factor Receptor Signaling Pathway Homeostatic Process Cellular Component Assembly Protein Heterooligomerization Regulation Of Cell Fate Specification Cellular Response To Peptide Hormone Stimulus Muscle Cell Differentiation Regulation Of MAPK Cascade
Tagcloud ?		anagen bulb bulbs coil coiled confined desmoplakin elongated encoded enter epidermis exons faithfully follicles fused galactosidase hair infundibulum kazrin keratinocyte morphogenetic movements obvious parakeratotic periplakin reside shape widespread xenopus	bioinformatics blotting cadherin downregulating embedded expressions fixed formalin igf1r immunohistochemistry lentiviruses luciferase metastasis mir os osteosarcoma paraffin paraformalin partially predicted probably promising prove quantitative real reporter sosp transfected u2
Tagcloud (Difference) ?		anagen bulb bulbs coil coiled confined desmoplakin elongated encoded enter epidermis exons faithfully follicles fused galactosidase hair infundibulum kazrin keratinocyte morphogenetic movements obvious parakeratotic periplakin reside shape widespread xenopus	bioinformatics blotting cadherin downregulating embedded expressions fixed formalin igf1r immunohistochemistry lentiviruses luciferase metastasis mir os osteosarcoma paraffin paraformalin partially predicted probably promising prove quantitative real reporter sosp transfected u2
Tagcloud (Intersection) ?