ERBB2IP and KCNA5

Number of citations of the paper that reports this interaction (PMID 15123239)
9

Data Source:
BioGRID (unspecified method)

		ERBB2IP	KCNA5
Gene Name		erbb2 interacting protein	potassium channel, voltage gated shaker related subfamily A, member 5
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Basement Membrane Nucleus Nucleoplasm Cytoplasm Plasma Membrane Basal Plasma Membrane Cell Junction Hemidesmosome Nuclear Membrane	Endoplasmic Reticulum Golgi Apparatus Plasma Membrane Integral Component Of Plasma Membrane Caveola Voltage-gated Potassium Channel Complex Intercalated Disc Z Disc Potassium Channel Complex Membrane Raft Intracellular Canaliculus Perinuclear Region Of Cytoplasm
	Molecular Function	ErbB-2 Class Receptor Binding Integrin Binding Structural Constituent Of Cytoskeleton Protein Binding	Receptor Binding Delayed Rectifier Potassium Channel Activity Protein Binding Outward Rectifier Potassium Channel Activity Potassium Channel Inhibitor Activity Protein Kinase Binding Alpha-actinin Binding Voltage-gated Potassium Channel Activity Involved In Atrial Cardiac Muscle Cell Action Potential Repolarization Scaffold Protein Binding
	Biological Process	Protein Targeting Cell Cycle Cell Adhesion Signal Transduction Epidermal Growth Factor Receptor Signaling Pathway Integrin-mediated Signaling Pathway Cell Growth Intermediate Filament Cytoskeleton Organization Basal Protein Localization Establishment Or Maintenance Of Epithelial Cell Apical/basal Polarity	Response To Hypoxia Potassium Ion Transport Synaptic Transmission Regulation Of Vasoconstriction Regulation Of Membrane Potential Regulation Of Potassium Ion Transport Negative Regulation Of Potassium Ion Transport Regulation Of Insulin Secretion Protein Homooligomerization Negative Regulation Of Cytosolic Calcium Ion Concentration Potassium Ion Homeostasis Membrane Hyperpolarization Regulation Of Atrial Cardiac Muscle Cell Membrane Repolarization Potassium Ion Export Potassium Ion Transmembrane Transport Atrial Cardiac Muscle Cell Action Potential Regulation Of Heart Rate By Cardiac Conduction Positive Regulation Of G1/S Transition Of Mitotic Cell Cycle Positive Regulation Of Myoblast Proliferation
Pathways		Signaling by ERBB2	Potassium Channels Voltage gated Potassium channels
Drugs
Diseases
GWAS
Protein-Protein Interactions		62 interactors: ABCA1 ABCC4 ABR ACTN1 ACTN2 ACVR2A ACVR2B AGTR2 APC ARHGEF7 ARVCF ATP2B1 ATP2B2 ATP2B4 BANF1 CASK CDH1 CHUK COPB1 CTNNB1 CTNND1 CTNND2 CTSG DLG4 DST ERBB2 FOXO3 GRIN2B GRIN2C GUCY1A2 ITGB4 KCNA4 KCNA5 LAMB1 LMO1 LMO2 LRRC1 MAP4 MAPK12 MCC MEF2A MPP1 MPP2 MPP3 NOD2 NR2E1 PICK1 PKP4 RAF1 SCN4A SHOC2 SLC5A5 SLC5A6 SLC6A12 SMAD1 SMAD2 SMAD3 SMAD4 SMAD7 STAT3 VIPR2 ZFYVE9	10 interactors: ACTN2 DLG1 DLG4 ERBB2IP KCNA2 PTPRE SNTA1 SRC SUMO3 TNK2
Entrez ID		55914	3741
HPRD ID		06090	08888
Ensembl ID		ENSG00000112851	ENSG00000130037
Uniprot IDs		B4DIP2 Q96RT1	P22460
PDB IDs		1MFG 1MFL 1N7T 2H3L 2QBW 3CH8
Enriched GO Terms of Interacting Partners?		Regulation Of Signaling Response To Stimulus Response To Organic Substance Signaling Cellular Response To Growth Factor Stimulus Cell Communication Response To Growth Factor Cellular Response To Organic Substance Enzyme Linked Receptor Protein Signaling Pathway Positive Regulation Of Metabolic Process Regulation Of Signal Transduction Response To Stress Positive Regulation Of Cellular Metabolic Process Cellular Response To Stimulus Positive Regulation Of Cellular Biosynthetic Process Cell Junction Assembly Regulation Of Cell Proliferation SMAD Protein Complex Assembly Negative Regulation Of Cell Proliferation Cell Surface Receptor Signaling Pathway Regulation Of Cellular Component Movement Signal Transduction Cellular Response To Organic Cyclic Compound Organ Development Anatomical Structure Morphogenesis Cellular Component Assembly Cell-cell Junction Organization Positive Regulation Of Transcription, DNA-templated Renal System Development Negative Regulation Of Signaling Regulation Of Cell Motility Gastrulation Cell-cell Signaling Regulation Of Cell Differentiation Negative Regulation Of Signal Transduction Regulation Of Locomotion Response To Wounding Urogenital System Development Regulation Of Cell Migration System Development Regulation Of Epithelial Cell Proliferation Adherens Junction Organization Positive Regulation Of Macromolecule Biosynthetic Process Intracellular Signal Transduction Multicellular Organismal Development Positive Regulation Of Transcription From RNA Polymerase II Promoter Kidney Development Positive Regulation Of Gene Expression Response To Organic Cyclic Compound Neurotrophin TRK Receptor Signaling Pathway	Regulation Of Membrane Potential Establishment Or Maintenance Of Apical/basal Cell Polarity Regulation Of Ion Transmembrane Transport Regulation Of Ion Transport Receptor Localization To Synapse Protein Localization To Synapse Establishment Or Maintenance Of Epithelial Cell Apical/basal Polarity Cortical Actin Cytoskeleton Organization Establishment Or Maintenance Of Cell Polarity Regulation Of Endocytosis Positive Regulation Of Potassium Ion Transport Cortical Cytoskeleton Organization Synaptic Transmission Cell-cell Junction Organization Muscle Contraction Actin Filament-based Process Regulation Of Sodium Ion Transmembrane Transport Peptidyl-tyrosine Autophosphorylation Muscle System Process Movement Of Cell Or Subcellular Component Receptor Clustering Nucleotide Phosphorylation Signaling Regulation Of Potassium Ion Transport Regulation Of Insulin Receptor Signaling Pathway Cell Communication Regulation Of Sodium Ion Transport Enzyme Linked Receptor Protein Signaling Pathway Positive Regulation Of Protein Modification Process Cell-cell Signaling Regulation Of Vesicle-mediated Transport Regulation Of Vasoconstriction By Circulating Norepinephrine Axon Guidance Regulation Of Cellular Response To Insulin Stimulus Cellular Component Assembly Protein Complex Assembly Action Potential Regulation Of Cellular Localization Adherens Junction Organization Regulation Of Cellular Protein Metabolic Process Positive Regulation Of Cellular Protein Metabolic Process Regulation Of Cell Activation Cytoskeleton Organization Optic Nerve Structural Organization Basal Protein Localization Cellular Response To Progesterone Stimulus Cell Projection Organization Cell Adhesion Regulation Of Cellular Process Regulation Of Receptor Activity
Tagcloud ?		adoptive cd4 cholangiocarcinoma contained exists exomic experienced harnessed helper humans infiltrating interacting lymphocytes mediate metastatic mount mutated mutation polyfunctional prolonged pure recognizing regression retreated sequencing stabilization til transfer	advance channel doi es ewing gated hypoxic kv kv1 nb onc online overexpress pcg polycomb potassium prerequisite publication reasoned relapse remission repression repressive resist restore sensitizes survive tumorigenicity voltage
Tagcloud (Difference) ?		adoptive cd4 cholangiocarcinoma contained exists exomic experienced harnessed helper humans infiltrating interacting lymphocytes mediate metastatic mount mutated mutation polyfunctional prolonged pure recognizing regression retreated sequencing stabilization til transfer	advance channel doi es ewing gated hypoxic kv kv1 nb onc online overexpress pcg polycomb potassium prerequisite publication reasoned relapse remission repression repressive resist restore sensitizes survive tumorigenicity voltage
Tagcloud (Intersection) ?