ERBB2IP and LAMB1

Number of citations of the paper that reports this interaction (PMID 15123239)
9

Data Source:
BioGRID (unspecified method)

		ERBB2IP	LAMB1
Gene Name		erbb2 interacting protein	laminin, beta 1
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Basement Membrane Nucleus Nucleoplasm Cytoplasm Plasma Membrane Basal Plasma Membrane Cell Junction Hemidesmosome Nuclear Membrane	Extracellular Region Basement Membrane Laminin-1 Complex Laminin-2 Complex Extracellular Space Extracellular Matrix Laminin-8 Complex Laminin-10 Complex Perinuclear Region Of Cytoplasm Extracellular Vesicular Exosome
	Molecular Function	ErbB-2 Class Receptor Binding Integrin Binding Structural Constituent Of Cytoskeleton Protein Binding	Integrin Binding Structural Molecule Activity Extracellular Matrix Structural Constituent Enzyme Binding Glycosphingolipid Binding
	Biological Process	Protein Targeting Cell Cycle Cell Adhesion Signal Transduction Epidermal Growth Factor Receptor Signaling Pathway Integrin-mediated Signaling Pathway Cell Growth Intermediate Filament Cytoskeleton Organization Basal Protein Localization Establishment Or Maintenance Of Epithelial Cell Apical/basal Polarity	Cell Adhesion Negative Regulation Of Cell Adhesion Axon Guidance Embryo Implantation Neuronal-glial Interaction Involved In Cerebral Cortex Radial Glia Guided Migration Extracellular Matrix Disassembly Extracellular Matrix Organization Positive Regulation Of Cell Migration Neuron Projection Development Substrate Adhesion-dependent Cell Spreading Endodermal Cell Differentiation Odontogenesis Positive Regulation Of Epithelial Cell Proliferation
Pathways		Signaling by ERBB2	Axon guidance Laminin interactions ECM proteoglycans L1CAM interactions Non-integrin membrane-ECM interactions Degradation of the extracellular matrix
Drugs
Diseases
GWAS			IgG glycosylation ( 23382691) Ulcerative colitis ( 19915572 20228799 19122664)
Protein-Protein Interactions		62 interactors: ABCA1 ABCC4 ABR ACTN1 ACTN2 ACVR2A ACVR2B AGTR2 APC ARHGEF7 ARVCF ATP2B1 ATP2B2 ATP2B4 BANF1 CASK CDH1 CHUK COPB1 CTNNB1 CTNND1 CTNND2 CTSG DLG4 DST ERBB2 FOXO3 GRIN2B GRIN2C GUCY1A2 ITGB4 KCNA4 KCNA5 LAMB1 LMO1 LMO2 LRRC1 MAP4 MAPK12 MCC MEF2A MPP1 MPP2 MPP3 NOD2 NR2E1 PICK1 PKP4 RAF1 SCN4A SHOC2 SLC5A5 SLC5A6 SLC6A12 SMAD1 SMAD2 SMAD3 SMAD4 SMAD7 STAT3 VIPR2 ZFYVE9	10 interactors: ACHE ANTXR2 ATXN7 ATXN7L2 CACNA1A COL6A1 EIF3I ERBB2IP GFI1B TGFB1
Entrez ID		55914	3912
HPRD ID		06090	01029
Ensembl ID		ENSG00000112851	ENSG00000091136
Uniprot IDs		B4DIP2 Q96RT1	P07942 Q8TAS6
PDB IDs		1MFG 1MFL 1N7T 2H3L 2QBW 3CH8
Enriched GO Terms of Interacting Partners?		Regulation Of Signaling Response To Stimulus Response To Organic Substance Signaling Cellular Response To Growth Factor Stimulus Cell Communication Response To Growth Factor Cellular Response To Organic Substance Enzyme Linked Receptor Protein Signaling Pathway Positive Regulation Of Metabolic Process Regulation Of Signal Transduction Response To Stress Positive Regulation Of Cellular Metabolic Process Cellular Response To Stimulus Positive Regulation Of Cellular Biosynthetic Process Cell Junction Assembly Regulation Of Cell Proliferation SMAD Protein Complex Assembly Negative Regulation Of Cell Proliferation Cell Surface Receptor Signaling Pathway Regulation Of Cellular Component Movement Signal Transduction Cellular Response To Organic Cyclic Compound Organ Development Anatomical Structure Morphogenesis Cellular Component Assembly Cell-cell Junction Organization Positive Regulation Of Transcription, DNA-templated Renal System Development Negative Regulation Of Signaling Regulation Of Cell Motility Gastrulation Cell-cell Signaling Regulation Of Cell Differentiation Negative Regulation Of Signal Transduction Regulation Of Locomotion Response To Wounding Urogenital System Development Regulation Of Cell Migration System Development Regulation Of Epithelial Cell Proliferation Adherens Junction Organization Positive Regulation Of Macromolecule Biosynthetic Process Intracellular Signal Transduction Multicellular Organismal Development Positive Regulation Of Transcription From RNA Polymerase II Promoter Kidney Development Positive Regulation Of Gene Expression Response To Organic Cyclic Compound Neurotrophin TRK Receptor Signaling Pathway	Cell Growth Neurotransmitter Metabolic Process Ossification Cellular Component Assembly Regulation Of Protein Secretion Cerebellar Molecular Layer Development Negative Regulation Of Synaptic Transmission, Cholinergic Neurotransmitter Receptor Biosynthetic Process Defense Response To Fungus, Incompatible Interaction Positive Regulation Of NAD+ ADP-ribosyltransferase Activity Synapse Assembly Receptor Metabolic Process Endoderm Development Cell Adhesion Growth Acetylcholine Catabolic Process Vestibular Nucleus Development Basal Protein Localization Active Induction Of Host Immune Response By Virus Acetylcholine Catabolic Process In Synaptic Cleft Regulation Of Histone Modification Negative Regulation Of Hyaluronan Biosynthetic Process Cerebellum Maturation Musculoskeletal Movement, Spinal Reflex Action Macrophage Derived Foam Cell Differentiation Evasion Or Tolerance Of Host Defenses By Virus Regulation Of Neurotransmitter Levels Osteoblast Differentiation Regulation Of Protein Transport Regulation Of Secretion Negative Regulation Of Macrophage Cytokine Production Ossification Involved In Bone Remodeling Tolerance Induction To Self Antigen Positive Regulation Of Extracellular Matrix Assembly Negative Regulation Of Extracellular Matrix Organization Negative Regulation Of Extracellular Matrix Disassembly Positive Regulation Of Exit From Mitosis Gamma-aminobutyric Acid Secretion Epidermal Growth Factor Receptor Signaling Pathway Regulation Of Establishment Of Protein Localization ERBB Signaling Pathway Connective Tissue Replacement Involved In Inflammatory Response Wound Healing Receptor Biosynthetic Process Regulation Of Extracellular Matrix Assembly Positive Regulation Of Smooth Muscle Cell Differentiation Frontal Suture Morphogenesis Negative Regulation Of Release Of Sequestered Calcium Ion Into Cytosol Regulation Of Acetylcholine Secretion, Neurotransmission Synapse Organization Cell Morphogenesis Involved In Differentiation
Tagcloud ?		adoptive cd4 cholangiocarcinoma contained exists exomic experienced harnessed helper humans infiltrating interacting lymphocytes mediate metastatic mount mutated mutation polyfunctional prolonged pure recognizing regression retreated sequencing stabilization til transfer	acad amp analogs boylan chambon cyclic dhss dhss2 dnase electrophoretic endoderm enhancer f9 flanking gudas homeobox hypersensitive laminin lohnes maximally natl parietal proc ra taneja teratocarcinoma transcriptionally transfections ttattaaca
Tagcloud (Difference) ?		adoptive cd4 cholangiocarcinoma contained exists exomic experienced harnessed helper humans infiltrating interacting lymphocytes mediate metastatic mount mutated mutation polyfunctional prolonged pure recognizing regression retreated sequencing stabilization til transfer	acad amp analogs boylan chambon cyclic dhss dhss2 dnase electrophoretic endoderm enhancer f9 flanking gudas homeobox hypersensitive laminin lohnes maximally natl parietal proc ra taneja teratocarcinoma transcriptionally transfections ttattaaca
Tagcloud (Intersection) ?