DYNLL1 and DAZ1

Number of citations of the paper that reports this interaction (PMID 16946704)
16

Data Source:
HPRD (two hybrid, in vitro)

		DYNLL1	DAZ1
Gene Name		dynein, light chain, LC8-type 1	deleted in azoospermia 1
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Kinetochore Nucleus Cytoplasm Mitochondrion Centrosome Cytosol Cytoplasmic Dynein Complex Microtubule Plasma Membrane COP9 Signalosome Membrane Extracellular Vesicular Exosome Primary Cilium Mitotic Spindle Ciliary Tip	Nucleus Cytoplasm
	Molecular Function	Motor Activity Protein Binding Protein C-terminus Binding Enzyme Binding Protein Domain Specific Binding Nitric-oxide Synthase Regulator Activity Protein Homodimerization Activity	Nucleotide Binding RNA Binding Protein Binding Translation Activator Activity
	Biological Process	G2/M Transition Of Mitotic Cell Cycle Mitotic Cell Cycle Transcription, DNA-templated Regulation Of Transcription, DNA-templated Transport Apoptotic Process Organelle Organization Microtubule-based Process Female Gamete Generation Anatomical Structure Morphogenesis Viral Process Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class II Substantia Nigra Development Actin Cytoskeleton Organization Negative Regulation Of Phosphorylation Regulation Of Catalytic Activity Intrinsic Apoptotic Signaling Pathway Positive Regulation Of Protein Insertion Into Mitochondrial Membrane Involved In Apoptotic Signaling Pathway	Multicellular Organismal Development Spermatogenesis Cell Differentiation Positive Regulation Of Translational Initiation
Pathways		Organelle biogenesis and maintenance Activation of BH3-only proteins Assembly of the primary cilium G2/M Transition Anchoring of the basal body to the plasma membrane Regulation of PLK1 Activity at G2/M Transition Cell Cycle, Mitotic Intraflagellar transport Loss of proteins required for interphase microtubule organizationÂ from the centrosome Activation of BIM and translocation to mitochondria Loss of Nlp from mitotic centrosomes MHC class II antigen presentation Programmed Cell Death Centrosome maturation Mitotic G2-G2/M phases Recruitment of mitotic centrosome proteins and complexes Adaptive Immune System Intrinsic Pathway for Apoptosis
Drugs
Diseases
GWAS
Protein-Protein Interactions		77 interactors: ACTB ACTC1 ACTG1 ALDOA AMBRA1 AMOTL2 B3GALT4 BCAS1 BCL2L11 BMF C14orf1 CA2 CACNB1 CCDC36 CLIP2 CS DAZ1 DLG4 DLGAP1 DNAJB9 DNM2 DNM3 DNMT1 DYNC1H1 DYNC1I1 EEF1A1 GAPDH GLUD1 GLUL GNB2L1 GPHN GRIN3A HIP1R HSPA8 INPP1 IQUB KANK2 LDHA MAP1B MARK3 MAST2 ME2 MTA1 MTR MYO10 MYO5A NDUFA4L2 NFKBIA NOS1 NRF1 NTRK1 NTRK2 NTRK3 PAK1 PAN2 PARD3 PAX6 PFKM PFKP PKIA PKIB PKIG POLH RAB4A RGS2 SHROOM3 TERT THAP8 TNFRSF14 TP53BP1 TUBA3C TUBB TXNDC17 VIM ZHX1 ZMYND11 ZNF354A	10 interactors: BOLL DAZAP1 DAZAP2 DAZL DYNLL1 DZIP1 DZIP1L DZIP3 PUM2 QKI
Entrez ID		8655	1617
HPRD ID		03334	15958
Ensembl ID		ENSG00000088986	ENSG00000188120
Uniprot IDs		P63167 Q6FGH9	Q1RMF9 Q86SG3 Q9NQZ3
PDB IDs		1CMI 3ZKE 3ZKF
Enriched GO Terms of Interacting Partners?		Nervous System Development Movement Of Cell Or Subcellular Component Cell Differentiation Developmental Process Regulation Of Cellular Component Organization Response To Organic Substance Regulation Of Cellular Localization Neuron Projection Morphogenesis Axonogenesis Cellular Response To Stimulus Synapse Organization Neuron Projection Development Neuron Development Regulation Of Cellular Protein Metabolic Process Response To Stimulus Neuron Differentiation Regulation Of Protein Metabolic Process Axon Development Cell Projection Morphogenesis Response To External Stimulus Anatomical Structure Morphogenesis Cell Projection Organization Cell Morphogenesis Involved In Neuron Differentiation Cell Part Morphogenesis Cellular Process Negative Regulation Of CAMP-dependent Protein Kinase Activity Positive Regulation Of Protein Homooligomerization Cell Morphogenesis Axon Guidance Negative Regulation Of Phosphorylation Regulation Of Cellular Process Glycolytic Process Locomotion Cell Development Negative Regulation Of Protein Phosphorylation Cytoskeleton Organization Regulation Of Phosphorus Metabolic Process Regulation Of Phosphorylation Membrane Organization Regulation Of CAMP-dependent Protein Kinase Activity Cell Morphogenesis Involved In Differentiation Anatomical Structure Development Generation Of Neurons System Development Response To Stress Regulation Of Protein Phosphorylation Multicellular Organismal Development Neuromuscular Junction Development Pyruvate Metabolic Process Actin Filament-based Process	Gamete Generation Sexual Reproduction Multicellular Organismal Reproductive Process Multicellular Organism Reproduction Spermatogenesis Male Gamete Generation Reproduction Single Organism Reproductive Process Regulation Of Translation Reproductive Process Positive Regulation Of Translational Initiation Posttranscriptional Regulation Of Gene Expression Developmental Process Involved In Reproduction Germ Cell Development Organelle Organization Regulation Of Translational Initiation Positive Regulation Of Translation Female Meiosis II Organelle Assembly 3'-UTR-mediated MRNA Destabilization Female Gamete Generation Developmental Process Positive Regulation Of Gene Expression Meiotic Nuclear Division Cilium Assembly Cilium Organization MRNA Destabilization Meiotic Cell Cycle Cilium Morphogenesis Multicellular Organismal Development Regulation Of Gene Expression Anatomical Structure Development RNA Destabilization Regulation Of Cellular Protein Metabolic Process Cell Differentiation Cell Projection Assembly Stress Granule Assembly Long-chain Fatty Acid Biosynthetic Process Regulation Of Protein Metabolic Process Positive Regulation Of Meiotic Nuclear Division Positive Regulation Of Protein Insertion Into Mitochondrial Membrane Involved In Apoptotic Signaling Pathway Anatomical Structure Morphogenesis Oocyte Maturation Positive Regulation Of Organelle Organization Positive Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway Positive Regulation Of MRNA Splicing, Via Spliceosome Cell Cycle Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway Positive Regulation Of RNA Splicing Female Meiotic Division
Tagcloud ?		1inq53a 250viqd 52gqvd adapter attempt capsid defective dynein hiv immunodeficiency integrase interaction kd ma motifs mutational p150glued particulate predicts proper q252a replication requirement reverse steps tctex transcriptase uncoating	cfsdna clpb coincident detecting dnmt3l epididymis fragments gml hoxa5 medip methylated methylation morc1 msh4 normozoospermia nz obviously peg10 prame promoters pv qpcr quantitatively semen seminal snurf testis ultrasonication vasectomy
Tagcloud (Difference) ?		1inq53a 250viqd 52gqvd adapter attempt capsid defective dynein hiv immunodeficiency integrase interaction kd ma motifs mutational p150glued particulate predicts proper q252a replication requirement reverse steps tctex transcriptase uncoating	cfsdna clpb coincident detecting dnmt3l epididymis fragments gml hoxa5 medip methylated methylation morc1 msh4 normozoospermia nz obviously peg10 prame promoters pv qpcr quantitatively semen seminal snurf testis ultrasonication vasectomy
Tagcloud (Intersection) ?