RILP and RAB34

Number of citations of the paper that reports this interaction (PMID 12475955)
21

Data Source:
HPRD (in vitro, two hybrid)

		RILP	RAB34
Gene Name		Rab interacting lysosomal protein	RAB34, member RAS oncogene family
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Mitochondrion Lysosome Lysosomal Membrane Late Endosome Phagocytic Vesicle Membrane Late Endosome Membrane Protein Complex	Golgi Apparatus Golgi Stack Phagocytic Vesicle Membrane Vesicle Golgi Cisterna Ruffle Membrane Phagocytic Vesicle Perinuclear Region Of Cytoplasm Extracellular Vesicular Exosome
	Molecular Function	Protein Binding Rab GTPase Binding	GTPase Activity Protein Binding GTP Binding Ral GTPase Binding GDP Binding
	Biological Process	Endosome To Lysosome Transport Protein Transport Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class II	Antigen Processing And Presentation Lysosome Localization Rab Protein Signal Transduction Golgi To Plasma Membrane Protein Transport Macropinocytosis Protein Localization To Plasma Membrane Phagosome Maturation Phagosome-lysosome Fusion
Pathways		MHC class II antigen presentation Adaptive Immune System
Drugs
Diseases
GWAS
Protein-Protein Interactions		7 interactors: KPNA2 LDB2 RAB34 RAB7A RCHY1 SNF8 VPS36	7 interactors: RABGAP1L RALA RILP SMAD1 SMAD2 SMAD4 TGFBR1
Entrez ID		83547	83871
HPRD ID		09706	06701
Ensembl ID		ENSG00000167705	ENSG00000109113
Uniprot IDs		Q96NA2	A8MYQ9 B4DNC0 C9JY26 E7ES60 J3KQW8 Q96PJ7 Q9BZG1
PDB IDs		1YHN
Enriched GO Terms of Interacting Partners?		Phagosome-lysosome Fusion Positive Regulation Of Exosomal Secretion Regulation Of Exosomal Secretion Phagolysosome Assembly Protein Transport Establishment Of Protein Localization Protein Targeting To Vacuole Intracellular Transport Endosomal Transport Establishment Of Protein Localization To Vacuole Cytoplasmic Transport Membrane Organization Protein Localization Intracellular Protein Transport Phagosome Maturation Establishment Of Localization In Cell Vesicle Fusion Establishment Of Protein Localization To Organelle Lysosome Organization Rab Protein Signal Transduction Positive Regulation Of Exocytosis Protein Targeting Cellular Localization Organelle Fusion Vacuolar Transport Epidermal Growth Factor Catabolic Process Cellular Protein Localization Protein Localization To Organelle Vacuole Organization Cellular Protein Catabolic Process Protein Catabolic Process Membrane Fusion Protein Targeting To Vacuole Involved In Ubiquitin-dependent Protein Catabolic Process Via The Multivesicular Body Sorting Pathway Regulation Of Exocytosis Tissue Homeostasis Phagosome Acidification Cellular Macromolecule Catabolic Process Vesicle Organization Endosome Transport Via Multivesicular Body Sorting Pathway Ras Protein Signal Transduction Late Endosome To Vacuole Transport Multicellular Organismal Homeostasis Protein To Membrane Docking Phagocytosis Nucleocytoplasmic Transport Nuclear Transport Antigen Processing And Presentation Protein Targeting To Lysosome Positive Regulation Of Secretion Protein Localization To Lysosome	SMAD Protein Complex Assembly Transforming Growth Factor Beta Receptor Signaling Pathway Cellular Response To Transforming Growth Factor Beta Stimulus Response To Transforming Growth Factor Beta Cellular Response To Growth Factor Stimulus Response To Growth Factor Embryonic Morphogenesis Regulation Of Epithelial To Mesenchymal Transition Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Cell Fate Commitment Kidney Development Primary MiRNA Processing Renal System Development Embryonic Pattern Specification Enzyme Linked Receptor Protein Signaling Pathway Endothelial Cell Activation Urogenital System Development Palate Development Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Ureteric Bud Development Anatomical Structure Formation Involved In Morphogenesis Positive Regulation Of SMAD Protein Import Into Nucleus Mesonephric Tubule Development Mesonephric Epithelium Development Mesonephros Development Regulation Of Cell Morphogenesis Embryo Development Pattern Specification Process Regulation Of SMAD Protein Import Into Nucleus Mesoderm Development Heart Development Kidney Epithelium Development Positive Regulation Of Cell Morphogenesis Involved In Differentiation Gastrulation Regulation Of Cellular Response To Growth Factor Stimulus Production Of MiRNAs Involved In Gene Silencing By MiRNA Response To Cholesterol Cardiac Epithelial To Mesenchymal Transition Tissue Morphogenesis Mesenchyme Development Negative Regulation Of Cell Proliferation Regulation Of Cell Differentiation Tube Development Positive Regulation Of Epithelial To Mesenchymal Transition Negative Regulation Of Cell Differentiation Activin Receptor Signaling Pathway Anterior/posterior Pattern Specification Chordate Embryonic Development Tissue Development Stem Cell Development
Tagcloud ?		anterograde arborization blunts brake branching dendrite dendrites dendritic frontotemporal interacting knockdown live lobar localizes lysosomal lysosomes map6 misrouting neurodegeneration presumably prevents rab7 rescues restores retrograde strengthen tmem106b trafficking transport	abnormal blot carcinoma chip coding detected endogenously expressions gaster gastric grb2 meanwhile mir mircornas mirna mirnas provided qrt regulated respectively rnas screening sgc7901 short special targets validated valuable western
Tagcloud (Difference) ?		anterograde arborization blunts brake branching dendrite dendrites dendritic frontotemporal interacting knockdown live lobar localizes lysosomal lysosomes map6 misrouting neurodegeneration presumably prevents rab7 rescues restores retrograde strengthen tmem106b trafficking transport	abnormal blot carcinoma chip coding detected endogenously expressions gaster gastric grb2 meanwhile mir mircornas mirna mirnas provided qrt regulated respectively rnas screening sgc7901 short special targets validated valuable western
Tagcloud (Intersection) ?