RILP and VPS36

Number of citations of the paper that reports this interaction (PMID 17010938)
16

Data Source:
BioGRID (pull down)

		RILP	VPS36
Gene Name		Rab interacting lysosomal protein	vacuolar protein sorting 36 homolog (S. cerevisiae)
Image
Gene Ontology Annotations	Cellular Component	Mitochondrion Lysosome Lysosomal Membrane Late Endosome Phagocytic Vesicle Membrane Late Endosome Membrane Protein Complex	Nucleus Lysosome Endosome Late Endosome Cytosol Membrane Extracellular Vesicular Exosome
	Molecular Function	Protein Binding Rab GTPase Binding	Protein Binding Phosphatidylinositol-3-phosphate Binding Ubiquitin Binding
	Biological Process	Endosome To Lysosome Transport Protein Transport Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class II	Transcription, DNA-templated Regulation Of Transcription, DNA-templated Protein Transport Endosomal Transport Membrane Organization
Pathways		MHC class II antigen presentation Adaptive Immune System	Endosomal Sorting Complex Required For Transport (ESCRT)
Drugs
Diseases
GWAS
Protein-Protein Interactions		7 interactors: KPNA2 LDB2 RAB34 RAB7A RCHY1 SNF8 VPS36	7 interactors: CHMP6 RILP SNF8 SPRY2 TSG101 UBC VPS25
Entrez ID		83547	51028
HPRD ID		09706	12620
Ensembl ID		ENSG00000167705	ENSG00000136100
Uniprot IDs		Q96NA2	Q86VN1
PDB IDs		1YHN	2HTH 2ZME 3CUQ
Enriched GO Terms of Interacting Partners?		Phagosome-lysosome Fusion Positive Regulation Of Exosomal Secretion Regulation Of Exosomal Secretion Phagolysosome Assembly Protein Transport Establishment Of Protein Localization Protein Targeting To Vacuole Intracellular Transport Endosomal Transport Establishment Of Protein Localization To Vacuole Cytoplasmic Transport Membrane Organization Protein Localization Intracellular Protein Transport Phagosome Maturation Establishment Of Localization In Cell Vesicle Fusion Establishment Of Protein Localization To Organelle Lysosome Organization Rab Protein Signal Transduction Positive Regulation Of Exocytosis Protein Targeting Cellular Localization Organelle Fusion Vacuolar Transport Epidermal Growth Factor Catabolic Process Cellular Protein Localization Protein Localization To Organelle Vacuole Organization Cellular Protein Catabolic Process Protein Catabolic Process Membrane Fusion Protein Targeting To Vacuole Involved In Ubiquitin-dependent Protein Catabolic Process Via The Multivesicular Body Sorting Pathway Regulation Of Exocytosis Tissue Homeostasis Phagosome Acidification Cellular Macromolecule Catabolic Process Vesicle Organization Endosome Transport Via Multivesicular Body Sorting Pathway Ras Protein Signal Transduction Late Endosome To Vacuole Transport Multicellular Organismal Homeostasis Protein To Membrane Docking Phagocytosis Nucleocytoplasmic Transport Nuclear Transport Antigen Processing And Presentation Protein Targeting To Lysosome Positive Regulation Of Secretion Protein Localization To Lysosome	Endosomal Transport Vacuolar Transport Ubiquitin-dependent Protein Catabolic Process Via The Multivesicular Body Sorting Pathway Establishment Of Localization In Cell Cellular Localization Protein Targeting To Vacuole Involved In Ubiquitin-dependent Protein Catabolic Process Via The Multivesicular Body Sorting Pathway Intracellular Transport Endosome Transport Via Multivesicular Body Sorting Pathway Membrane Organization Late Endosome To Vacuole Transport Positive Regulation Of Exosomal Secretion Regulation Of Exosomal Secretion Viral Protein Processing Ubiquitin-dependent Protein Catabolic Process Modification-dependent Protein Catabolic Process Proteolysis Involved In Cellular Protein Catabolic Process Cellular Protein Catabolic Process Protein Transport Protein Catabolic Process Viral Life Cycle Establishment Of Protein Localization Protein Targeting To Vacuole Virion Assembly Establishment Of Protein Localization To Vacuole Intracellular Transport Of Virus Cellular Macromolecule Catabolic Process Protein Localization Negative Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Negative Regulation Of ERBB Signaling Pathway Establishment Of Protein Localization To Organelle Cell Cycle Process Positive Regulation Of Exocytosis Protein Targeting Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Regulation Of ERBB Signaling Pathway Negative Regulation Of Cardiac Muscle Cell Myoblast Differentiation Cell Cycle Protein Localization To Organelle Viral Process Negative Regulation Of Cellular Response To Growth Factor Stimulus Regulation Of Gene Expression Regulation Of Nitrogen Compound Metabolic Process Transport Proteolysis Positive Regulation Of Protein Ubiquitination Mitotic Cell Cycle Process Positive Regulation Of Proteolysis Involved In Cellular Protein Catabolic Process Cytoplasmic Transport Negative Regulation Of Canonical Wnt Signaling Pathway Positive Regulation Of Cellular Protein Catabolic Process
Tagcloud ?		anterograde arborization blunts brake branching dendrite dendrites dendritic frontotemporal interacting knockdown live lobar localizes lysosomal lysosomes map6 misrouting neurodegeneration presumably prevents rab7 rescues restores retrograde strengthen tmem106b trafficking transport	bicoid budding complementation eap20 eap30 eap45 endosomal escrt escrtii evolutionarily exemplifies fertilised implication inward juxtanuclear localisation opts orthologue outwards rab7 staufen staufen1 tedly topologically trafficking tri unexpec vesicular vps22
Tagcloud (Difference) ?		anterograde arborization blunts brake branching dendrite dendrites dendritic frontotemporal interacting knockdown live lobar localizes lysosomal lysosomes map6 misrouting neurodegeneration presumably prevents rescues restores retrograde strengthen tmem106b transport	bicoid budding complementation eap20 eap30 eap45 endosomal escrt escrtii evolutionarily exemplifies fertilised implication inward juxtanuclear localisation opts orthologue outwards staufen staufen1 tedly topologically tri unexpec vesicular vps22
Tagcloud (Intersection) ?		rab7 trafficking