ARF6 and AP3D1

Number of citations of the paper that reports this interaction (PMID 11926829)
12

Data Source:
HPRD (in vitro, in vivo)

		ARF6	AP3D1
Gene Name		ADP-ribosylation factor 6	adaptor-related protein complex 3, delta 1 subunit
Image
Gene Ontology Annotations	Cellular Component	Ruffle Endosome Early Endosome Golgi Apparatus Plasma Membrane Focal Adhesion Cell Cortex Membrane Endocytic Vesicle Midbody Filopodium Membrane Cleavage Furrow Recycling Endosome Membrane Extracellular Vesicular Exosome	Golgi Membrane Nucleoplasm Lysosomal Membrane Golgi Apparatus Endosome Membrane Membrane Membrane Coat Terminal Bouton
	Molecular Function	GTPase Activity Protein Binding GTP Binding Thioesterase Binding	Transporter Activity
	Biological Process	Liver Development Movement Of Cell Or Subcellular Component Cell Cycle Cell Adhesion Small GTPase Mediated Signal Transduction Metabolic Process Protein Transport Vesicle-mediated Transport Positive Regulation Of Actin Filament Polymerization Cortical Actin Cytoskeleton Organization Ruffle Organization Myeloid Cell Apoptotic Process Protein Localization To Cell Surface Regulation Of Rac Protein Signal Transduction Protein Localization To Endosome Negative Regulation Of Receptor-mediated Endocytosis Cell Division Regulation Of Filopodium Assembly Regulation Of Dendritic Spine Development Positive Regulation Of Establishment Of Protein Localization To Plasma Membrane Establishment Of Epithelial Cell Polarity Hepatocyte Apoptotic Process	Eye Pigment Biosynthetic Process Intracellular Protein Transport Anterograde Axon Cargo Transport Melanosome Organization Protein Localization To Organelle Endosome To Melanosome Transport Antigen Processing And Presentation, Exogenous Lipid Antigen Via MHC Class Ib Anterograde Synaptic Vesicle Transport Synaptic Vesicle Membrane Organization Positive Regulation Of NK T Cell Differentiation Regulation Of Sequestering Of Zinc Ion Protein Localization To Membrane
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions		28 interactors: AP1B1 AP3B1 AP3D1 AP3S2 APP ARFIP2 ARRB1 ARRB2 ASAP2 ASAP3 ATP6V0C CAPN1 CHRM3 CYTH1 CYTH2 EXOC5 EZR GGA1 IKBKG ITSN1 MPP5 PIP5K1A PIP5K1C PLD1 RAB11FIP3 RAB11FIP4 RAB11FIP5 ZNF709	9 interactors: AP3S1 AP3S2 ARF1 ARF6 CTGF RUFY1 SLC30A3 VAMP7 VPS41
Entrez ID		382	8943
HPRD ID		02714	06260
Ensembl ID			ENSG00000065000
Uniprot IDs		P62330	O14617
PDB IDs		1E0S 2A5D 2A5F 2A5G 2BAO 2BAU 2J5X 2W83 3LVQ 3LVR 3N5C 3PCR 4FME 4KAX	4AFI
Enriched GO Terms of Interacting Partners?		Vesicle-mediated Transport Cellular Localization Protein Localization Establishment Of Localization In Cell Establishment Of Protein Localization Transport Establishment Of Vesicle Localization Vesicle Localization Synaptic Vesicle Transport Protein Transport Movement Of Cell Or Subcellular Component Axon Cargo Transport Endocytosis Establishment Of Organelle Localization Receptor Metabolic Process Regulation Of GTPase Activity Anterograde Synaptic Vesicle Transport Regulation Of ARF Protein Signal Transduction Intracellular Transport Chemotaxis Anterograde Axon Cargo Transport Regulation Of Ras Protein Signal Transduction Organelle Localization Cellular Protein Localization Positive Regulation Of GTPase Activity Positive Regulation Of Hydrolase Activity Regulation Of Small GTPase Mediated Signal Transduction Microtubule-based Transport Receptor Internalization Cytoskeleton-dependent Intracellular Transport Response To External Stimulus Antigen Processing And Presentation, Exogenous Lipid Antigen Via MHC Class Ib Positive Regulation Of NK T Cell Differentiation Positive Regulation Of Catalytic Activity Regulation Of Body Fluid Levels Synaptic Transmission Actin Cytoskeleton Organization Locomotion Cell-cell Signaling Platelet Activation Cytoskeletal Anchoring At Plasma Membrane Regulation Of Signaling Actin Filament-based Process Regulation Of Intracellular Signal Transduction G-protein Coupled Receptor Internalization Blood Coagulation Hemostasis Regulation Of Signal Transduction Post-Golgi Vesicle-mediated Transport Desensitization Of G-protein Coupled Receptor Protein Signaling Pathway	Protein Transport Vesicle-mediated Transport Establishment Of Protein Localization Regulation Of Vesicle-mediated Transport Protein Localization Transport Cellular Localization Regulation Of Cellular Component Organization Establishment Of Localization In Cell Anterograde Synaptic Vesicle Transport Regulation Of Endocytosis Anterograde Axon Cargo Transport Establishment Of Vesicle Localization Vesicle Localization Cellular Protein Localization Intracellular Transport Golgi Vesicle Transport Axon Cargo Transport Establishment Of Organelle Localization Intracellular Protein Transport Regulation Of Organelle Organization Regulation Of Actin Cytoskeleton Organization Organelle Fusion Regulation Of Actin Filament-based Process Regulation Of Protein Targeting To Vacuolar Membrane Vacuole Fusion, Non-autophagic Vacuolar Transport Organelle Localization Post-Golgi Vesicle-mediated Transport Regulation Of Cytoskeleton Organization Synaptic Vesicle Transport Organ Senescence Membrane Fusion Microtubule-based Transport Positive Regulation Of Histamine Secretion By Mast Cell Regulation Of Histamine Secretion By Mast Cell Triglyceride Transport Extracellular Matrix Constituent Secretion Eosinophil Degranulation Cytoskeleton-dependent Intracellular Transport Response To Anoxia Positive Regulation Of G0 To G1 Transition Movement Of Cell Or Subcellular Component Regulation Of Sequestering Of Zinc Ion Neutrophil Degranulation Positive Regulation Of Cardiac Muscle Contraction Positive Regulation Of Cytoskeleton Organization Vesicle Organization Myeloid Cell Apoptotic Process Regulation Of SNARE Complex Assembly
Tagcloud ?		accessible cellubrevin cho colocalized compartment cryoimmunogold endocytic endosomal gdp gtpase horseradish hrp invaginations localize localizes morphologically pericentriolar perinuclear perturbs q67l recycling resembled ribosylation shortly t27n tracer uniquely vesicles	18s actb bestkeeper c2c12 cdc40 csnk2a2 dystrophic dystrophin exceptionally fbxo38 fbxw2 gapdh genorm h2k2b4 h2ksf1 htatsf1 informative mef2c myoblasts myod myogenesis myogenic myogenin normalization normalizing normfinder packages pak1ip1 zfp91
Tagcloud (Difference) ?		accessible cellubrevin cho colocalized compartment cryoimmunogold endocytic endosomal gdp gtpase horseradish hrp invaginations localize localizes morphologically pericentriolar perinuclear perturbs q67l recycling resembled ribosylation shortly t27n tracer uniquely vesicles	18s actb bestkeeper c2c12 cdc40 csnk2a2 dystrophic dystrophin exceptionally fbxo38 fbxw2 gapdh genorm h2k2b4 h2ksf1 htatsf1 informative mef2c myoblasts myod myogenesis myogenic myogenin normalization normalizing normfinder packages pak1ip1 zfp91
Tagcloud (Intersection) ?