AP3D1 and CTGF

Number of citations of the paper that reports this interaction (PMID 16457822)
27

Data Source:
HPRD (in vitro)

		AP3D1	CTGF
Gene Name		adaptor-related protein complex 3, delta 1 subunit	connective tissue growth factor
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Golgi Membrane Nucleoplasm Lysosomal Membrane Golgi Apparatus Endosome Membrane Membrane Membrane Coat Terminal Bouton	Extracellular Region Proteinaceous Extracellular Matrix Extracellular Space Golgi Apparatus Cis-Golgi Network Cytosol Plasma Membrane Cell Cortex Intracellular Membrane-bounded Organelle Perinuclear Region Of Cytoplasm
	Molecular Function	Transporter Activity	Fibronectin Binding Integrin Binding Protein Binding Insulin-like Growth Factor Binding Growth Factor Activity Heparin Binding
	Biological Process	Eye Pigment Biosynthetic Process Intracellular Protein Transport Anterograde Axon Cargo Transport Melanosome Organization Protein Localization To Organelle Endosome To Melanosome Transport Antigen Processing And Presentation, Exogenous Lipid Antigen Via MHC Class Ib Anterograde Synaptic Vesicle Transport Synaptic Vesicle Membrane Organization Positive Regulation Of NK T Cell Differentiation Regulation Of Sequestering Of Zinc Ion Protein Localization To Membrane	Cartilage Condensation Ossification Angiogenesis Regulation Of Cell Growth Tissue Homeostasis Positive Regulation Of Protein Phosphorylation Transcription Initiation From RNA Polymerase II Promoter Cell Adhesion Cell-matrix Adhesion Integrin-mediated Signaling Pathway Cell-cell Signaling Positive Regulation Of Cell Proliferation Fibroblast Growth Factor Receptor Signaling Pathway Epidermis Development Response To Wounding Response To Glucose Organ Senescence Gene Expression Positive Regulation Of Gene Expression Negative Regulation Of Gene Expression Cell Migration Cell Differentiation Lung Development Regulation Of Chondrocyte Differentiation Response To Estradiol Positive Regulation Of Collagen Biosynthetic Process Response To Anoxia Intracellular Signal Transduction Chondrocyte Proliferation Response To Amino Acid Positive Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Response To Peptide Hormone Cellular Lipid Metabolic Process Small Molecule Metabolic Process Positive Regulation Of Cell Differentiation Positive Regulation Of JNK Cascade Positive Regulation Of Cell Activation Response To Mineralocorticoid Positive Regulation Of Stress Fiber Assembly Cytosolic Calcium Ion Transport Positive Regulation Of Cardiac Muscle Contraction Negative Regulation Of Cell Death Extracellular Matrix Constituent Secretion Positive Regulation Of G0 To G1 Transition Positive Regulation Of ERK1 And ERK2 Cascade Response To Fatty Acid DNA Biosynthetic Process Reactive Oxygen Species Metabolic Process
Pathways			PPARA activates gene expression Fatty acid, triacylglycerol, and ketone body metabolism Generic Transcription Pathway Metabolism of lipids and lipoproteins YAP1- and WWTR1 (TAZ)-stimulated gene expression Regulation of lipid metabolism by Peroxisome proliferator-activated receptor alpha (PPARalpha)
Drugs
Diseases
GWAS
Protein-Protein Interactions		9 interactors: AP3S1 AP3S2 ARF1 ARF6 CTGF RUFY1 SLC30A3 VAMP7 VPS41	11 interactors: ACTB AP3D1 ERBB4 FBLN1 HSPG2 LRP1 NOV TGFB1 TGFB2 TGFB3 VEGFA
Entrez ID		8943	1490
HPRD ID		06260	00412
Ensembl ID		ENSG00000065000	ENSG00000118523
Uniprot IDs		O14617	P29279 Q5M8T4
PDB IDs		4AFI
Enriched GO Terms of Interacting Partners?		Protein Transport Vesicle-mediated Transport Establishment Of Protein Localization Regulation Of Vesicle-mediated Transport Protein Localization Transport Cellular Localization Regulation Of Cellular Component Organization Establishment Of Localization In Cell Anterograde Synaptic Vesicle Transport Regulation Of Endocytosis Anterograde Axon Cargo Transport Establishment Of Vesicle Localization Vesicle Localization Cellular Protein Localization Intracellular Transport Golgi Vesicle Transport Axon Cargo Transport Establishment Of Organelle Localization Intracellular Protein Transport Regulation Of Organelle Organization Regulation Of Actin Cytoskeleton Organization Organelle Fusion Regulation Of Actin Filament-based Process Regulation Of Protein Targeting To Vacuolar Membrane Vacuole Fusion, Non-autophagic Vacuolar Transport Organelle Localization Post-Golgi Vesicle-mediated Transport Regulation Of Cytoskeleton Organization Synaptic Vesicle Transport Organ Senescence Membrane Fusion Microtubule-based Transport Positive Regulation Of Histamine Secretion By Mast Cell Regulation Of Histamine Secretion By Mast Cell Triglyceride Transport Extracellular Matrix Constituent Secretion Eosinophil Degranulation Cytoskeleton-dependent Intracellular Transport Response To Anoxia Positive Regulation Of G0 To G1 Transition Movement Of Cell Or Subcellular Component Regulation Of Sequestering Of Zinc Ion Neutrophil Degranulation Positive Regulation Of Cardiac Muscle Contraction Positive Regulation Of Cytoskeleton Organization Vesicle Organization Myeloid Cell Apoptotic Process Regulation Of SNARE Complex Assembly	Negative Regulation Of Macrophage Cytokine Production Salivary Gland Morphogenesis SMAD Protein Import Into Nucleus Salivary Gland Development Exocrine System Development Platelet Activation Platelet Degranulation Gland Development Anatomical Structure Morphogenesis Regulation Of Body Fluid Levels Regulation Of Cell Migration Wound Healing Developmental Process Regulation Of Cell Motility Response To External Stimulus Uterine Wall Breakdown Positive Regulation Of Cell Division Regulation Of Locomotion Positive Regulation Of Protein Transport Regulation Of Cellular Component Movement Response To Wounding Positive Regulation Of Transport Extracellular Matrix Organization Extracellular Structure Organization Regulation Of Immune System Process Positive Regulation Of Epithelial To Mesenchymal Transition Regulation Of Protein Localization Face Morphogenesis Head Development Gland Morphogenesis Positive Regulation Of Cell Morphogenesis Involved In Differentiation Blood Coagulation Hemostasis Mammary Gland Development Vesicle-mediated Transport Head Morphogenesis Positive Regulation Of MAPK Cascade Multicellular Organismal Development Movement Of Cell Or Subcellular Component Positive Regulation Of Pathway-restricted SMAD Protein Phosphorylation Ossification Involved In Bone Remodeling Enzyme Linked Receptor Protein Signaling Pathway Regulation Of Cell Death Positive Regulation Of Kinase Activity Growth Response To Progesterone Face Development Frontal Suture Morphogenesis Positive Regulation Of Stem Cell Differentiation Regulation Of Pathway-restricted SMAD Protein Phosphorylation
Tagcloud ?		18s actb bestkeeper c2c12 cdc40 csnk2a2 dystrophic dystrophin exceptionally fbxo38 fbxw2 gapdh genorm h2k2b4 h2ksf1 htatsf1 informative mef2c myoblasts myod myogenesis myogenic myogenin normalization normalizing normfinder packages pak1ip1 zfp91	additively away bsc connective diphosphate edge egr encode fibronectin fn gro hour hsp int message monolayer nak nonwounded osteopontin pa pai plasminogen potentiate quiescent scrape stimulator urokinase wound wounding
Tagcloud (Difference) ?		18s actb bestkeeper c2c12 cdc40 csnk2a2 dystrophic dystrophin exceptionally fbxo38 fbxw2 gapdh genorm h2k2b4 h2ksf1 htatsf1 informative mef2c myoblasts myod myogenesis myogenic myogenin normalization normalizing normfinder packages pak1ip1 zfp91	additively away bsc connective diphosphate edge egr encode fibronectin fn gro hour hsp int message monolayer nak nonwounded osteopontin pa pai plasminogen potentiate quiescent scrape stimulator urokinase wound wounding
Tagcloud (Intersection) ?