ARF6 and RAB11FIP3

Number of citations of the paper that reports this interaction (PMID 11535061)
16

Data Source:
HPRD (in vitro)

		ARF6	RAB11FIP3
Gene Name		ADP-ribosylation factor 6	RAB11 family interacting protein 3 (class II)
Image
Gene Ontology Annotations	Cellular Component	Ruffle Endosome Early Endosome Golgi Apparatus Plasma Membrane Focal Adhesion Cell Cortex Membrane Endocytic Vesicle Midbody Filopodium Membrane Cleavage Furrow Recycling Endosome Membrane Extracellular Vesicular Exosome	Nucleoplasm Endosome Centrosome Microtubule Organizing Center Cytosol Midbody Cleavage Furrow Intracellular Membrane-bounded Organelle Intercellular Bridge Recycling Endosome Recycling Endosome Membrane
	Molecular Function	GTPase Activity Protein Binding GTP Binding Thioesterase Binding	Calcium Ion Binding Protein Binding Rab GTPase Binding ADP-ribosylation Factor Binding Protein Homodimerization Activity
	Biological Process	Liver Development Movement Of Cell Or Subcellular Component Cell Cycle Cell Adhesion Small GTPase Mediated Signal Transduction Metabolic Process Protein Transport Vesicle-mediated Transport Positive Regulation Of Actin Filament Polymerization Cortical Actin Cytoskeleton Organization Ruffle Organization Myeloid Cell Apoptotic Process Protein Localization To Cell Surface Regulation Of Rac Protein Signal Transduction Protein Localization To Endosome Negative Regulation Of Receptor-mediated Endocytosis Cell Division Regulation Of Filopodium Assembly Regulation Of Dendritic Spine Development Positive Regulation Of Establishment Of Protein Localization To Plasma Membrane Establishment Of Epithelial Cell Polarity Hepatocyte Apoptotic Process	Cytokinesis Organelle Organization Vesicle-mediated Transport Endocytic Recycling
Pathways			Cargo trafficking to the periciliary membrane Organelle biogenesis and maintenance VxPx cargo-targeting to cilium Assembly of the primary cilium
Drugs
Diseases
GWAS
Protein-Protein Interactions		28 interactors: AP1B1 AP3B1 AP3D1 AP3S2 APP ARFIP2 ARRB1 ARRB2 ASAP2 ASAP3 ATP6V0C CAPN1 CHRM3 CYTH1 CYTH2 EXOC5 EZR GGA1 IKBKG ITSN1 MPP5 PIP5K1A PIP5K1C PLD1 RAB11FIP3 RAB11FIP4 RAB11FIP5 ZNF709	9 interactors: ARF4 ARF5 ARF6 IKBKG RAB11A RAB11B RAB11FIP4 RAB25 TOMM34
Entrez ID		382	9727
HPRD ID		02714	18521
Ensembl ID			ENSG00000090565
Uniprot IDs		P62330	O75154
PDB IDs		1E0S 2A5D 2A5F 2A5G 2BAO 2BAU 2J5X 2W83 3LVQ 3LVR 3N5C 3PCR 4FME 4KAX	2D7C 2HV8
Enriched GO Terms of Interacting Partners?		Vesicle-mediated Transport Cellular Localization Protein Localization Establishment Of Localization In Cell Establishment Of Protein Localization Transport Establishment Of Vesicle Localization Vesicle Localization Synaptic Vesicle Transport Protein Transport Movement Of Cell Or Subcellular Component Axon Cargo Transport Endocytosis Establishment Of Organelle Localization Receptor Metabolic Process Regulation Of GTPase Activity Anterograde Synaptic Vesicle Transport Regulation Of ARF Protein Signal Transduction Intracellular Transport Chemotaxis Anterograde Axon Cargo Transport Regulation Of Ras Protein Signal Transduction Organelle Localization Cellular Protein Localization Positive Regulation Of GTPase Activity Positive Regulation Of Hydrolase Activity Regulation Of Small GTPase Mediated Signal Transduction Microtubule-based Transport Receptor Internalization Cytoskeleton-dependent Intracellular Transport Response To External Stimulus Antigen Processing And Presentation, Exogenous Lipid Antigen Via MHC Class Ib Positive Regulation Of NK T Cell Differentiation Positive Regulation Of Catalytic Activity Regulation Of Body Fluid Levels Synaptic Transmission Actin Cytoskeleton Organization Locomotion Cell-cell Signaling Platelet Activation Cytoskeletal Anchoring At Plasma Membrane Regulation Of Signaling Actin Filament-based Process Regulation Of Intracellular Signal Transduction G-protein Coupled Receptor Internalization Blood Coagulation Hemostasis Regulation Of Signal Transduction Post-Golgi Vesicle-mediated Transport Desensitization Of G-protein Coupled Receptor Protein Signaling Pathway	Small GTPase Mediated Signal Transduction Protein Transport Establishment Of Protein Localization Melanosome Transport Pigment Granule Transport Establishment Of Melanosome Localization Melanosome Localization Intracellular Signal Transduction Establishment Of Vesicle Localization Protein Localization Vesicle Localization Cellular Pigmentation Rab Protein Signal Transduction Vesicle-mediated Transport Establishment Of Organelle Localization Regulation Of Vesicle-mediated Transport Pigmentation Organelle Localization Transport Cellular Protein Localization Ras Protein Signal Transduction Cellular Localization Exocytosis Intracellular Protein Transport Multivesicular Body Assembly Regulation Of Multivesicular Body Size Establishment Of Localization In Cell Positive Regulation Of Epithelial Cell Migration Cell Division Signal Transduction Cytokinesis Secretion By Cell Protein Localization To Organelle Constitutive Secretory Pathway Multivesicular Body Organization Signaling Cell Communication Pseudopodium Organization Regulation Of Endosome Size Regulation Of Epithelial Cell Migration Secretion Exosomal Secretion Intracellular Transport Insulin Secretion Involved In Cellular Response To Glucose Stimulus Cellular Response To Stimulus Regulation Of Protein Localization Endosomal Transport Myeloid Cell Apoptotic Process Cellular Response To Acidic PH Plasma Membrane To Endosome Transport
Tagcloud ?		accessible cellubrevin cho colocalized compartment cryoimmunogold endocytic endosomal gdp gtpase horseradish hrp invaginations localize localizes morphologically pericentriolar perinuclear perturbs q67l recycling resembled ribosylation shortly t27n tracer uniquely vesicles
Tagcloud (Difference) ?		accessible cellubrevin cho colocalized compartment cryoimmunogold endocytic endosomal gdp gtpase horseradish hrp invaginations localize localizes morphologically pericentriolar perinuclear perturbs q67l recycling resembled ribosylation shortly t27n tracer uniquely vesicles
Tagcloud (Intersection) ?